Clinical trials: Chronic TMD Pain
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Central Nervous System Sensitization
Correlation Between Central Sensitization Inventory and Posturographic Data
To investigate the use of balance as a screening tool for Central Sensitization, a condition of the nervous system that is associated with the development and maintenance of chronic pain.
- Trial name
- NCT03058003
- Testing
- Posturography Evaluation, Central Sensitization Inventory
- Where
- 2 sites in United States, Australia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Caps Research Network
Temporomandibular Disorders
Shamanic Healing for Women With Temporomandibular Joint Disorders (TMDs)
This is a Phase I study to examine the feasibility and safety of shamanic (spiritual) healing for treating temporomandibular joint disorders (TMDs).
- Trial name
- NCT00071474
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
TMD, Masticatory Muscle Pain
Pain, Central Sensitization and Psychoemotional State in Patients With Chronic Masticatory Muscle Pain
The aim of this study is to investigate the relationship of psychological aspects, selected blood parameters, pain, central sensitization, and muscle electromyography activity in patients with chronic masticatory muscle pain.
- Trial name
- NCT05676827
- Testing
- Diagnostic Criteria for Temporomandibular Disorders Clinical Examination, Blood test
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Neck Pain, Temporomandibular Disorder
Manual Therapy and Movement Control Exercises for Chronic Neck Pain. A Pilot Randomized Controlled Trial
Chronic neck pain is a common and highly prevalent clinical entity among the population. It causes a high economic and financial burden. Commonly people with neck pain present temporomandibular disorders (TMD).
- Trial name
- NCT06189612
- Testing
- Clinical reasoning based physiotherapy + cervical movement control training, Clinical reasoning based physiotherapy + orofacial movement control training, Clinical reasoning based physiotherapy + standard exercises
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hochschule Osnabruck
Chronic Temporomandibular Disorders (TMD)
Endogenous Pain Inhibition Deficiency in Chronic TMD Pain
Temporomandibular disorders (TMDs) involve a range of conditions with varied causes, affecting a large portion of the U.S. population and posing challenges for diagnosis and management, especially in chronic cases.
- Trial name
- TMD-CPM (NCT06617494)
- Testing
- Pain modulation testing
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Temporomandibular Disorder (TMD), Chronic Pain
Occlusal Sensitivity to Articulating Foils in Patients With Temporomandibular Disorders and Healthy Controls
Occlusal sensitivity refers to the ability to detect fine objects placed between opposing teeth during biting or in maximum intercuspation.
- Trial name
- SENFOIL (NCT07163494)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Neck Disability, Temporomandibular Disorders (TMD)
Neck Disability and Temporomandibular Disorders
This cross-sectional study investigates neck-related disability in individuals with chronic neck pain by examining the combined influence of temporomandibular disorders, sleep quality, and cervical sensorimotor function within a…
- Trial name
- NCT07444944
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Fibromyalgia, Temporomandibular Disorder
An Algorithm for Approaching Temporomandibular Disorders With Osteopathic Manual Therapy in Patients With Fibromyalgia
Nowadays, fibromyalgia is the rheumatic disorder with the highest levels of deterioration in quality of life. Among the comorbidities it presents, one of the most frequent is temporomandibular disorders.
- Trial name
- NCT06365151
- Testing
- Osteopathic manual therapy
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Primary Headache Disorders, Tension Headache
Pericranial and General Sensitivity in Patients With Primary Headache
Primary headaches such as migraine and tension type headache are among the most common neurological disorders and frequently cause significant disability and reduced quality of life.
- Conditions
- Primary Headache Disorders, Tension Headache, Tension-type Headache, Migraine
- Trial name
- HEAD-TMD (NCT07514208)
- Testing
- Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Bruxism, Pelvic Pain
Bruxism, Pelvic Pain, Erectile Dysfunction, and Anxiety in Young Adult Men
Bruxism is a parafunctional activity characterized by clenching or grinding of the teeth during wakefulness or sleep. Increasing evidence suggests that bruxism is not only related to orofacial structures but may also be…
- Conditions
- Bruxism, Pelvic Pain, Myofascial Pain - Dysfunction Syndrome of TMJ, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07469345
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Temporomandibular Joint Disorders, Mastication Disorder
Altered MAstication Contribute to TMJ PAin
The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors.
- Trial name
- MAPA (NCT03139994)
- Testing
- Diagnostic
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Chronic Pain, Temporomandibular Joint Disorders
Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders
This study addresses the timely problem of painful temporomandibular disorders (TMD), the most common cause of orofacial pain second only to tooth pain.
- Conditions
- Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
- Trial name
- NCT05068908
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Temporomandibular Disorders
Temporomandibular Disorders With and Without Chronic Neck Pain
Temporomandibular disorders (TMD) are common musculoskeletal conditions frequently accompanied by cervical dysfunction. Although previous studies have demonstrated associations between cervical impairments and temporomandibular…
- Trial name
- NCT07750743
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Hacettepe University