Clinical trials: Cigarette Use
Smoking, Cigarette, Electronic Cigarettes
Evaluating New Nicotine Standards for Cigarettes - Project 3
This study is designed to examine how the nicotine content of cigarettes and the nicotine concentration and flavors in e-liquids influence responses to and use of these products in adolescent smokers.
- Trial name
- CENIC2-P3 (NCT03194256)
- Testing
- Spectrum Research Cigarettes
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brown University
Childhood Obesity, Smoking, Cigarette
Maternal Smoking Cessation and Pediatric Obesity Prevention
The objective of this study is to test the effect of smoking cessation in pregnancy or in lactation on preventing rapid infant adiposity gain.
- Conditions
- Childhood Obesity, Smoking, Cigarette, Pregnancy
- Trial name
- NCT03514602
- Testing
- Multicomponent behavioral intervention, Education only control
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Smoking, Cigarette, Breastfeeding
Postpartum Smoking Relapse Prevention by Breastfeeding Promotion
This is a randomized controlled trial to prevent postpartum smoking relapse by breastfeeding promotion. The intervention group (N=30) will receive multicomponent breastfeeding intervention from late pregnancy to 6 months…
- Trial name
- NCT04670822
- Testing
- Breastfeeding promotion
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Electronic Cigarette
Nicotine Pharmacokinetic in Blood and Analysis of Exhaled Breath After E-cigarette Smoking.
Electronic or e-cigarettes are battery-powered devices that deliver vapor which may be inhaled in the manner tobacco is smoked. The e-liquid is usually a solution containing propylene glycol and/or vegetable glycerin, nicotine…
- Trial name
- VAPexp'Air (NCT03573154)
- Testing
- administration of the liquid 1 and then the liquid 2, administration of the liquid 2 and then the liquid 1
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Tobacco Use
Predictors and Consequences of Combustible Cigarette Smokers' Switch to Standardized Research E-Cigarettes
The primary goal of this study is to examine whether cigarette smokers can reduce their use of conventional, combustible cigarettes by switching to a Standardized Research E-Cigarette (SREC); whether participants can maintain…
- Trial name
- NCT03277495
- Testing
- Brief behavioral counseling
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alcohol Use, E-cigarette Use
Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use
A high priority research area for the Food and Drug Administration Center for Tobacco Products (FDA CTP) is determining who will start using tobacco products and who will stop using tobacco products.
- Conditions
- Alcohol Use, E-cigarette Use, Cigarette Use
- Trial name
- NCT07010601
- Testing
- Experimental Tobacco Marketplace, Hypothetical Novel Nicotine Product Purchase Tasks
- Where
- United States
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Mark J Rzeszutek, PhD
Nicotine Dependence, Cigarettes
Negotiating a Quit Date or Not in Online Interventions
The primary purpose of the current study is to test the effect of providing users of automated web-based smoking cessation interventions with the option of negotiating and re-negotiating the quit date.
- Trial name
- NCT03194919
- Testing
- Endre: a digital smoking cessation counsellor
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Cigarette Smoking, Addiction
Electronic Cigarettes as a Harm Reduction Strategy in Individuals With Substance Use Disorder
Patients in addiction treatment have exceptionally higher rate of cigarette smoking and very low quit rates compared to the general population.
- Conditions
- Cigarette Smoking, Addiction, E Cig Use
- Trial name
- NCT04063267
- Testing
- E cigarettes, Nicotine Replacement Therapy
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Tobacco Dependence
Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status
The overall goal of this study is to address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in smokers of low socioeconomic status
- Trial name
- NCT01928719
- Testing
- Reduced Nicotine Content Cigarettes, Same Nicotine Content Cigarettes
- Where
- 2 sites in United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Tobacco Use Disorder, Cigarette Smoking
Pharmacokinetics of Nicotine Sublingual Tablets Versus Nicorette Lozenge in Healthy Smokers
The purpose of the study is to compare two different dosage forms from which nicotine is released and absorbed into the bloodstream.
- Trial name
- NCT02906995
- Testing
- Sublingual tablet 4 mg versus Nicorette Lozenge 4mg
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Friends Research Institute, Inc.
Tobacco Dependence
Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes
The current study aims to establish proof-of-concept that neural cue-reactivity can serve as an early, objective marker of electronic cigarette (ECIG) addictive potential.
- Trial name
- NCT03905928
- Testing
- Nicotine Containing ECIG with tobacco flavor, Nicotine Containing ECIG with Strawberry Vanilla Flavor
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Adverse Effect of Other Agents Primarily Affecting the Cardiovascular System, Initial Encounter
Cardiovascular Assessment of the Effects of Tobacco and Nicotine Delivery Products
The overarching goal of this project is to develop a panel of cardiovascular risk biomarkers that can detect differences in the cardiovascular safety of various tobacco products, whether conventional, new or emerging, in order to…
- Trial name
- NCT01964807
- Testing
- Cigarette, NIDA test type with 16.6 mg nicotine, Cigarette, NIDA test type with <0.45 mg nicotine, Electronic cigarette with 18 mg/ml nicotine
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Electronic Cigarette Use, Cigarette Smoking
Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2
This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.
- Conditions
- Electronic Cigarette Use, Cigarette Smoking, Cigarette Use, Electronic, Vaping
- Trial name
- NCT05958992
- Testing
- E-cigarette
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Smoking Cessation, Smoking, Cigarette
Incorporating Financial Incentives to Increase Smoking Cessation Among Asian Americans Residing in New York City
Financial incentives for motivating health change have been increasingly employed in various healthcare sectors. They can be a potentially effective approach to promote smoking behavioral change and increase the use of…
- Trial name
- NCT03397511
- Testing
- Financial Incentives
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Electronic Cigarette Use, Cigarette Smoking
Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 1
This study assess the ways in which e-cigarette product characteristics, such as marketing strategies, impact user experience to inform potential regulations.
- Conditions
- Electronic Cigarette Use, Cigarette Smoking, Cigarette Use, Electronic, Vaping
- Trial name
- NCT05958979
- Testing
- Control Marketing Strategies, Experimental Marketing Strategies
- Where
- United States
- Volunteers
- 601 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy Volunteers
A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes
This study evaluates the overall performance of the currently-marketed MybluTM e-cigarette device and pods, as assessed by nicotine uptake, exposure to smoke constituents, safety and consumer satisfaction, over 8 days.
- Trial name
- NCT04429932
- Testing
- Myblu flavor A_2.4, Myblu flavor B_2.4, Myblu flavor C_2.4
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Fontem US LLC
Smoking
Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol)
The primary objective of the study is to evaluate the pharmacokinetic (PK) profiles (rate and amount of nicotine absorbed) after a single use of the THS 2.2 Menthol (mTHS 2.2) compared to a single use of the menthol conventional…
- Trial name
- NCT01967719
- Testing
- mTHS 2.2, mCC, NNS
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Tobacco Use
Cigarette and E-cigarette Nicotine Content in an Electronic Tobacco Marketplace (ETM)
This study is proposing a four condition Electronic Tobacco Marketplace (ETM) study to determine if banning normal nicotine content (NNC) is sufficient for encouraging smokers to switch to potentially less harmful products or if…
- Trial name
- NCT05320887
- Testing
- Normal Nicotine Content Vape with all flavor e-liquids, Normal nicotine content vape with tobacco e-liquids, Low nicotine content vape with all flavor e-liquids
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy Volunteers, Smoking
E-cigarette Nicotine Pharmacokinetic Study
This study will compare nicotine delivery and product satisfaction in healthy subjects either using several different types of electronic cigarettes or smoking a conventional cigarette.
- Trial name
- NCT03178981
- Testing
- Use electronic cigarette or smoke conventional cigarette
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- British American Tobacco (Investments) Limited
Smoking, Cigarette, Smoking Cessation
A Cognitive Behavioral Stress Intervention for Women Who Smoke
1. PURPOSE OF THE STUDY 1.1 Justification The purpose of the project is to examine the effect of breathing biofeedback and thoughts about stress on performance under stress and cigarette cravings.
- Conditions
- Smoking, Cigarette, Smoking Cessation, Stress, Stress, Emotional
- Trial name
- NCT03077945
- Testing
- heart rate variability biofeedback and cognitive reappraisal, control tasks
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey