Clinical trials: Cigarette Use
Cigarette Smoking, Smoking Behaviors
A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse
This is a research study to find out if treatment decision making can be improved for smokers who find it difficult to quit with medications.
- Conditions
- Cigarette Smoking, Smoking Behaviors, Treatment
- Trial name
- ADAPT (NCT06118502)
- Testing
- Switching to a different medication, Continued use of the same medication, Switching to a harm reduction tobacco product
- Where
- United States
- Volunteers
- 544 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Smoking Behavior, Cigarette Smoking Behavior
OCAST Cessation Study
The long-term goal is to improve the quality of life of children and their parents who smoke tobacco by facilitating parental smoking cessation in a way that is easy to administer yet effective.
- Conditions
- Tobacco Smoking Behavior, Cigarette Smoking Behavior, Second Hand Tobacco Smoke, Tobacco Use Cessation
- Trial name
- OCAST (NCT01921439)
- Testing
- Personalized Feedback
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Healthy Volunteers
A Study to Evaluate Nicotine Uptake and Biomarkers in Smokers Using mybluTM Electronic Cigarettes
This study evaluates the overall performance of the currently-marketed MybluTM e-cigarette device and pods, as assessed by nicotine uptake, exposure to smoke constituents, safety and consumer satisfaction, over 8 days.
- Trial name
- NCT04430634
- Testing
- Myblu variant A, Myblu variant B, Myblu variant C
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fontem US LLC
Tobacco Use
Robot-Assisted Immersive Escape Room Game for Tobacco Harm Prevention Among Elementary School Students
This study evaluates the effectiveness of a robot-assisted immersive escape room intervention for tobacco harm prevention among upper-grade elementary school students.
- Trial name
- NCT07501572
- Testing
- Robot-assisted Immersive Escape Room Game, Traditional Tobacco Harm Prevention Education
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Smoking Cigarette, Smoking Tobacco
Process and Effect Evaluation of the KickAsh! Intervention
The goal of this evaluation study is to evaluate the KickAsh! intervention, an intervention aiming to prevent smoking initiation in adolescents living in vulnerable socioeconomic situations.
- Conditions
- Smoking Cigarette, Smoking Tobacco, Smoking, Smoking Prevention
- Trial name
- NCT05920772
- Testing
- KickAsh! intervention
- Where
- 2 sites in Belgium
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cigarette Smoking
Using Computers to Assist in Parental Smoking Cessation in a Pediatric Setting
The CHICA system is a clinical decision support system that uses adaptive turnaround documents to provide point-of-care information to clinicians.
- Trial name
- NCT01334216
- Testing
- CHICA Smoking Cessation Module
- Where
- United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cigarette Smoking, Vaping
Menthol and Mint Experimental Tobacco Marketplace (ETM) Study
Menthol cigarettes comprise almost one-third of the United States (US) market share and are disproportionately smoked by racial minorities.
- Trial name
- NCT04879225
- Testing
- Tobacco e-liquids, Menthol and Tobacco e-liquids, Mint, Menthol and Tobacco e-liquids
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Tobacco Use
A Laboratory Model of Increasing Delta-9-tetrahydrocannabinol (THC) Potency on Cigarette Smoking
The objective of the proposed research is to investigate how smoking increasing potency of THC (i.e., the psychoactive ingredient in marijuana) changes tobacco cigarette smoking behavior, urges, subjective effects, and abuse…
- Trial name
- MJCIG (NCT02961309)
- Testing
- THC
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Battelle Memorial Institute
Behavior, Addictive, Cigarette Smoking
Practicing Self-Control Lowers the Risk of Smoking Lapse
The proposed study will investigate the role of self-control in smoking cessation and whether interventions that improve self-control can help reduce the risk of lapsing among smokers who wish to quit.
- Trial name
- NCT00349687
- Testing
- self-control practice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University at Albany
Smoking, Tobacco Use
Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial (CONNECT)
The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. E-cigarettes are classified by the US Food and Drug Administration (FDA) as a tobacco product, though…
- Trial name
- CONNECT (NCT03453385)
- Testing
- Electronic Cigarette
- Where
- United States
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Tobacco Use
A Study to Assess Changes in Cigarette Consumption During a Switch to Very Low Nicotine Cigarettes
This study evaluates the impact of switching from usual brand cigarettes to very low nicotine cigarettes on cigarette consumption, smoking behavior, and biomarkers of exposure.
- Trial name
- NCT03571724
- Testing
- Non-Menthol Very Low Nicotine Cigarettes, Menthol Very Low Nicotine Cigarettes, Subject's UB non-mentholated filtered cigarettes
- Where
- 2 sites in United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- 22nd Century Group, Inc.
Nicotine Dependence
Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
The use of smokeless tobacco (ST) as a substitute for cigarette smoking has been suggested since it is considered by some to be a less harmful tobacco product (Russell, Jarvis and Feyerabend, 1980; Russell et al, 1981; Rodu…
- Trial name
- ANTS3 (NCT00469079)
- Testing
- Nicotine gum and lozenge, Taboka, Camel Snus
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Electronic Cigarette Use, Cigarette Use, Electronic
Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to JUUL ENDS
A Randomized, Open Label, Parallel Group Study in Adult Smokers to Evaluate Changes in Biomarkers of Cigarette Smoke Exposure After Switching Either Exclusively or Partly to using JUUL Electronic Nicotine Delivery Systems With…
- Conditions
- Electronic Cigarette Use, Cigarette Use, Electronic, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04107779
- Testing
- Switch from UB of Combustible Cigarette to JUUL 5% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 3% Virginia Tobacco ENDS, Switch from UB of Combustible Cigarette to JUUL 5% Mint ENDS
- Where
- 5 sites in United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-1 (NCT03839745)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking, Tobacco Use
The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers
This between-subjects study aims to evaluate the effect of flavor on initial and sustained switching from combustible cigarettes to e-cigarettes among 210 cigarette smokers.
- Conditions
- Smoking, Tobacco Use, Cigarette Smoking, E-Cig Use
- Trial name
- NCT06264154
- Testing
- E-cigarettes
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking
Exploratory THS 2.1 Nicotine Pharmacokinetics and Safety Study
The main goal of this exploratory study is to evaluate the pharmacokinetic profile of nicotine for the candidate modified risk tobacco product THS 2.1 and for conventional cigarettes (CC).
- Trial name
- NCT01780688
- Testing
- Conventional cigarettes (CC), THS 2.1
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Cannabis Use, Tobacco Use
Effect of Cannabis on Cigarette Use Behavior
The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of cigarettes.
- Conditions
- Cannabis Use, Tobacco Use, Cigarette Smoking
- Trial name
- NCT06609083
- Testing
- THC 30mg, THC 5mg, THC 0mg
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Tobacco Use, Smoking
CSD200902: Assessment of Indoor Air Quality for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Environmental Testing Chamber
This is a single-center, open-label, parallel-cohort study to measure and compare the levels of selected secondhand smoke (SHS) constituents of a heated tobacco product (HTP) against combustible cigarettes (CC) after ad libitum…
- Conditions
- Tobacco Use, Smoking, Tobacco Smoking
- Trial name
- NCT05363254
- Testing
- Marlboro Gold Box, Newport Box, Non-combusted cigarette variant 42001401
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
College Student Drinking, Eating Disorder
Your Health in On Click
A health education program was provided to higher education students aged between 18 and 25 years. Students were recruited either by posters and leaflets on campus, or during their mandatory medical survey at the University…
- Conditions
- College Student Drinking, Eating Disorder, Stress, Psychological, Burn Out Syndrome
- Trial name
- TS1C (NCT03218670)
- Where
- France
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Marie-Pierre TAVOLACCI
Smoking, Cigarette, Smoking Cessation
Pictorial Warning Labels, Numeracy, and Memory for Numeric Cigarette Health-risk Information Over Time
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks, or for numeric risks (e.g., percentage risk for…
- Trial name
- NCT03501472
- Testing
- text-only PWL, low-emot PWL, high-emot PWL
- Volunteers
- 866 people, healthy volunteers welcome
- Sponsor
- Ohio State University