Clinical trials: Ciprofol
Adenotonsillectomy, Propofol
Comparison of Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy
The goal of this clinical trial is to compare the Ciprofol and Propofol Under IoC1 and IoC2 Monitoring for Adenotonsillectomy Participants will be randomly allocated to two groups: Ciprofol group (Group C) and Propofol group…
- Conditions
- Adenotonsillectomy, Propofol, Ciprofol
- Trial name
- NCT06882980
- Testing
- Ciprofol group, Propofol group
- Where
- China
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Intubation, Intratracheal, Adverse Effects
The Study of Ciprofol for the Suppression of Cardiovascular Responses to Tracheal Intubation
Preliminary studies have illuminated the promising nature of ciprofol, indicating its enhanced safety spectrum, superior potency, and a diminished likelihood of experiencing injection-related discomfort.
- Trial name
- NCT06095570
- Testing
- Ciprofol, Remimazolam
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Hainan Medical University
Ciprofol
Ciprofol's Influence on LVOT VTI in Elderly Painless Colonoscopy Patients
1. Objective: Primary: Compare the effect of Ciprofol vs Propofol on LVOT VTI at 2 minutes post-injection (T1) in elderly patients (≥65 years).
- Trial name
- NCT07081477
- Testing
- Intravenous Anesthetic Induction with Ciprofol for Painless Colonoscopy in Elderly Patients, Propofol Intravenous Anesthesia Induction for Painless Colonoscopy in Elderly Patients
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
PND, POCD - Postoperative Cognitive Dysfunction
Effects of Ciprofol on Perioperative Neurocognitive Function in Elderly Patients Undergoing Daytime Surgery
As life expectancy increases, the rate of disability among elderly individuals is also rising. Elderly patients undergoing home-based rehabilitation after surgery without medical supervision may experience complications and…
- Trial name
- NCT07895407
- Testing
- Ciprofol, propofol
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Anesthesia
A Study to Evaluate the Differences in Pharmadynamics, Pharmacokinetics, and Safety Between Ciprofol and Propofol
This is a single-center, open-label, randomized, two-stage, two-way crossover Phase I study in healthy male subjects.The main objective is to evaluate the differences in pharmadynamics (PD), pharmacokinetics (PK), and safety…
- Trial name
- NCT04294056
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Painless Abortion, Artificial Intelligence (AI)
Reinforcement Learned Automated Anesthesia Systems During Painless Abortion
This study compares the automated anesthesia systems for painless abortion (AAS-PA) with traditional anesthesia in painless abortions.
- Conditions
- Painless Abortion, Artificial Intelligence (AI), Ciprofol
- Trial name
- AAS-PA (NCT07132151)
- Testing
- AI Controlled General Anesthesia, General Anesthesia
- Where
- 8 sites in China
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Boston Intelligent Medical Research Center, Shenzhen United Scheme Technology Co., Ltd.
Drug Drug Interaction
Drug-drug Interaction Between Ciprofol and Mefanamic Acid or Valproate
study the effect of mefanamic acid or valproate on ciprofol
- Trial name
- NCT05181007
- Testing
- Mefanamic Acid, Valproate
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Ciprofol, Hysteroscopy
Efficacy and Safety of Ciprofol for the Sedation in Patients Undergoing Hysteroscopy
Eligible patients undergoing hysteroscopy were randomly assigned in a 1:1 ratio to receive intravenous anesthesia with either propofol (2 mg/kg) or remifentanil (0.4 mg/kg).Continuous monitoring of pulse oximetry (SpO2), blood…
- Trial name
- NCT06172140
- Testing
- Ciprofol group, Propofol group
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Quality of Postoperative Recovery
The Impact of Low-Dose Esketamine Combined With Ciprofol on the Quality of Early Postoperative Recovery Among Elderly Patients Undergoing Painless Gastroscopy
To explore the impact of esketamine combined with ciprofol on the quality of early postoperative recovery in elderly patients undergoing painless gastroscopy, as well as the effectiveness and safety of this regimen.
- Trial name
- NCT06617039
- Testing
- Remifentanil and ciprofol, esketamine 0.3mg/kg and ciprofol, esketamine 0.5mg/kg and ciprofol
- Where
- China
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Northern Jiangsu People's Hospital
Anesthesia, Acute Pain
Comparative Effects of Ciprofol and Propofol on Pain Intensity on the First Day After Surgery: a Retrospective, Propensity Score Matched, Cohort Study
Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in…
- Conditions
- Anesthesia, Acute Pain, Risk Reduction
- Trial name
- NCT06020469
- Where
- China
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Guangdong Second Provincial General Hospital
Hypoproteinemia, Pharmacokinetics
Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia
Blood concentrations of Ciprofol were measured at different time points after single injection in patients with hypoproteinemia
- Conditions
- Hypoproteinemia, Pharmacokinetics, Ciprofol
- Trial name
- NCT06425757
- Testing
- ciprofol
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Xie Kangjie
Postoperative Cognitive Dysfunction
Effect of Ciprofol Injection on Postoperative Cognitive Function
This study aims to explore the effect of ciprofol on the postoperative cognitive function of inpatients undergoing gastrointestinal endoscopy examination, to compare the anesthetic effects and differences in adverse reactions of…
- Trial name
- NCT07673978
- Testing
- Ciprofol group, Propofol group
- Where
- China
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Ciprofol
Changes of Ciprofol Dosage and Bispectral Index Required for Loss of Consciousness in Patients of Different Ages
This study aims to explore dose requirements for loss of consciousness and bispectral index changes during general anesthesia induction with ciprofol in patients of different ages, providing a reference for its rational clinical…
- Trial name
- NCT07148596
- Testing
- It is an observational study without any intervention measures.
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Neurocognitive Function
Comparison of the Effects of Ciprofol and Propofol on Cognitive Function After Painless Gastroenteroscopy
This randomized platform trial compared ciprofol and propofol for early neurocognitive recovery in adults undergoing painless gastrointestinal endoscopy.
- Trial name
- NCT07887594
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Induction of Anaesthesia
Explore the Clinical Application Value of Ciprofol in Painless Colonoscopy
This study used propofol as a positive control, and adopted a large-sample, multi-center, randomized, double-blind, positive parallel controlled trial design to explore the clinical application value of ciprofol in painless…
- Trial name
- NCT05294679
- Testing
- Propofol, Ciprofol
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital