Clinical trials: Clinical Decision-making
Major Depressive Disorder
Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression
This study was conducted to understand the use of a mobile app (titled Pathway) to help patients track depression symptoms, medications, side effects, and goals in addition to the usual care with their doctor.
- Trial name
- NCT04891224
- Testing
- Pathway Platform mobile app
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Wake Forest University Health Sciences
Diabetes Mellitus, Normal Glucose Metabolism
Assessment of Non-Fasting vs. Fasting Lipid Measures in Diabetes Patients
This study will examine whether fasting and non-fasting lipid measures can provide similar clinical information in order to guide lipid management by primary physicians. It will compare fasting vs.
- Conditions
- Diabetes Mellitus, Normal Glucose Metabolism, Hyperlipidemia
- Trial name
- NCT00569959
- Testing
- fasting 12+ hours, Non-fasting
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Advanced Cancer
Web-Based Advance Care Planning for Patients With Advanced Cancer
The goal of this clinical trial is to determine whether a web-based advance care planning (ACP) intervention can reduce preferences for aggressive life-sustaining treatments among patients with advanced cancer.
- Trial name
- NCT07712237
- Testing
- Web-Based Advance Care Planning Program, Patient Right to Autonomy Act Leaflet
- Where
- Taiwan
- Volunteers
- 110 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Colorectal Cancer, Pancreatic Cancer
Making Decisions About Participating in a Cancer Clinical Trial for Patients With Stage II, Stage III, or Stage IV Pancreatic Cancer or Stage III or Stage IV Colon Cancer or Rectal Cancer
RATIONALE: Determining how patients makes decisions about participating in a clinical trial may help doctors plan clinical trials in which more patients are willing to participate and are satisfied with their decision to…
- Conditions
- Colorectal Cancer, Pancreatic Cancer, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00478010
- Testing
- counseling intervention, study of socioeconomic and demographic variables, psychosocial assessment and care
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Acute Appendicitis
Acute Appendicitis: The Influence of C-reactive Protein and Leucocytes on Clinical Decision-making
Aim: To investigate if the results of CRP and leucocytes had any positive or negative influence on the surgeon's decision-making when handling patients with suspected AA.
- Trial name
- NCT02304653
- Testing
- Clinical descision making
- Where
- Denmark
- Volunteers
- 226 people
- Sponsor
- Odense University Hospital
Gut Feelings
Assessment of "Gut Feelings" Accuracy Regarding the Effect of Professional Experience in General Practitioners in Clinical Decision Making
Knowledge, experience and professional development limit the risk of diagnostic error for the clinician in daily practice. However, research has shown that other non-analytical factors are involved in clinical decision making.
- Trial name
- EGFGP (NCT05175157)
- Testing
- Gut Fellings questionnaire
- Where
- France
- Volunteers
- 260 people
- Sponsor
- University Hospital, Brest
Decision Making, Shared, Pregnancy
Navigating the Grey Zone for Antenatal Corticosteroids
The purpose of this study is to find out if including a decision support tool in clinical practice guidelines will improve how doctors discuss the option of antenatal corticosteroid treatment with patients who might deliver at 34…
- Conditions
- Decision Making, Shared, Pregnancy, Preterm Birth
- Trial name
- NCT04792112
- Testing
- Decision support tool
- Where
- 2 sites in Canada
- Volunteers
- 460 people
- Sponsor
- University of British Columbia
Decisional Conflict, Advanced/Metastatic Solid Tumors, Shared Decision-making
Effect of an Interdisciplinary Shared Decision-Making Intervention on Decisional Conflict in Advanced Cancer Patients Receiving Third-Line Therapy
The study aims to evaluate whether an interdisciplinary intervention based on a shared decision-making model can reduce decisional conflict in patients with metastatic solid tumors (lung, breast, colorectal, prostate, or ovarian…
- Trial name
- SharedDecision (NCT07164365)
- Testing
- Interdisciplinary Shared Decision-Making Consultation
- Where
- Colombia
- Volunteers
- 62 people
- Sponsor
- Hospital Universitario San Ignacio
Crohn Disease
SIIT Based on UST CDST in Patients With CD
ustekinumab (UST) can effectively induce and maintain clinical remission and mucosal healing of Crohn's disease (CD), but some patients still have poor response.
- Trial name
- NCT05861167
- Testing
- selective intensive induction therapy based on ustekinumab clinical decision-making tools
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Advanced Solid Tumors or Hematologic Malignancies
Clinical Research Platform on Decision Making and Clinical Impact of Biomarker-Driven Precision Oncology
The retrospective cohort study INFINITY will be an instrument to analyze the current practice of precision oncology in the real-world setting.
- Trial name
- INFINITY (NCT04389541)
- Where
- 97 sites in Germany
- Volunteers
- 499 people
- Sponsor
- iOMEDICO AG
Cancer
PRecision Oncology Evidence Development in Cancer Treatment - Liquid
The current standard of care for molecular characterization of tumors is tissue based next generation sequencing (NGS) panel. Liquid biopsies (ie blood) are of increasing interest and have been implemented as a diagnostic tool in…
- Trial name
- PREDiCTl (NCT05057234)
- Testing
- FoundationOne liquid CDx, Quality of life questionnaires
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- British Columbia Cancer Agency
Breast Cancer
Prospective Study of the Prosigna Assay on Neoadjuvant Clinical Decision-making in Women With HR+/Her2- Breast Cancer
This research study is evaluating a genomic analysis called Predictor Analysis of Microarray 50 (PAM50, by Prosigna®) as a tool to possibly guide the participant and the treating physician to choose the most personalized…
- Trial name
- NCT03749421
- Testing
- Prosigna PAM-50 assay
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dana-Farber Cancer Institute
Knowledge Transfer, Clinical Decision-making
The Effect and Mediators of Two Knowledge Translation Strategies
Purpose: This study will compare the effectiveness and mediators of two different knowledge transfer (KT) interventions in terms of their impact on changing knowledge and behavior (utilization and clinical reasoning) related to…
- Trial name
- NCT00298727
- Testing
- SHIPS, ePBL
- Where
- Canada
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- McMaster University
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Dynamic Evolution of Pulmonary Nodules and Influence Factors of Its Clinical Decision-making
The researchers are aimed to investigate the dynamic evolution of indeterminate pulmonary nodules by a long-term follow-up of patients with different characteristics.
- Trial name
- DEPICT (NCT04857333)
- Testing
- CT scan, Antibiotics, Surgical Resection
- Where
- China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- GuiBin Qiao
Trauma, Congenital Bone and Joint Abnormalities
Telemedicine Consultation in Trauma and Orthopedic
The purpose of this study is to determine whether telemedicine consultations (lead by standard scheme)allows to increase quality of anatomical and functional outcomes and improve clinical work-flow at patients with acute bone and…
- Conditions
- Trauma, Congenital Bone and Joint Abnormalities, Joint Diseases, Orthopedic Surgery Complications
- Trial name
- TeleTO (NCT00815243)
- Testing
- Telemedicine consultation, Treatment plan
- Where
- 5 sites in Ukraine
- Volunteers
- 300 people
- Sponsor
- Donetsk National Medical University
Advance Care Planning
Advanced Care Planning for the Severely Ill Home-dwelling Elderly
This study will develop and evaluate a complex intervention to implement advance care planning for severely ill home-dwelling elderly acutely admitted to hospital, by using a cluster randomized design.
- Trial name
- NCT05681585
- Testing
- Implementation support program
- Where
- 12 sites in Norway
- Volunteers
- 2,000 people
- Sponsor
- University of Oslo
Real-world Study
AI-Assisted Medical Decision-Making
The study builds and applies an AI model to help doctors predict patient diagnoses and outcomes, such as survival or hospital stay.
- Trial name
- NCT06846229
- Testing
- AI-associated strategy
- Where
- 2 sites in China
- Volunteers
- 50,000,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Rectal Cancer
Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients
The adoption of total mesorectal excision (TME) has standardized rectal cancer surgery and improved oncological outcomes. In locally advanced rectal cancer, neoadjuvant radio chemotherapy (NACRT) has further improved oncological…
- Trial name
- EVAREC (NCT06740357)
- Testing
- Tumor response monitoring program, Standard evaluation of tumor response, Shared decision-making
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI)
Artificial Intelligence-based Model for the Prediction of Occult Lymph Node Metastasis and Improvement of Clinical Decision-making in Non-small Cell Lung Cancer
This nationwide, multicenter observational study aims to develop and validate a multimodal artificial intelligence (AI) model for detecting occult lymph node metastasis in early-stage non-small cell lung cancer (NSCLC) patients.
- Conditions
- NSCLC (Non-small Cell Lung Cancer), Artificial Intelligence (AI), Lymphnode Metastasis
- Trial name
- NCT06684418
- Testing
- chest enhanced CT
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Fudan University
Nursing Process, Clinical Decision Making
The Effect of Simulation-based Education Within the Framework of the Clinical Judgment Model on Nursing Students' Clinical Decision-making Skills and Perceptions of Nursing Process Competence.
The purpose of this study is to examine the effects of simulation training delivered within the framework of the clinical judgment model on nursing students' clinical decision-making skills and perceptions of nursing process…
- Conditions
- Nursing Process, Clinical Decision Making, Simulation Edication
- Trial name
- NCT07297498
- Testing
- Siimulation education
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University