Clinical trials: Clinical Pain
Pain
Patient and Provider Confidence and Satisfaction With the Clinical Use of CYP Genetic Variability
This study utilizes the Medication DNA Insight™ tests for pain and mental health medications. We are testing the pain and mental health medications commonly used in pain treatment.
- Trial name
- Genomics (NCT02568618)
- Testing
- Pain Medication DNA Insight (TM) test
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Pain
A Multi-center Clinical Longitudinal Study of Neuropathic Pain by Collecting Data
A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function
- Trial name
- NCT06290024
- Testing
- A multi-center clinical longitudinal study of neuropathic pain by collecting data on patients' brain physiology and cognitive function
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Pain, Joint Function Disorder
Genicular Nerve Block in Rheuamtoid Arthritis
N=64 RA patients either early or established disease diagnosed after ACR/EULAR criteria 2010 with unilateral persistent knee arthritis.
- Conditions
- Pain, Joint Function Disorder, Inflammation
- Trial name
- NCT04361513
- Testing
- Bupivacaine hydrochloride 0.5% (Marcaine, Pfizer), triamcinolone 40 milligrams (Kenacort, Bristol Myers Squip)
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Sohag University
Radiculopathy, Herniated Disk
Percutaneous Diskectomy SpineJet x Open Microdiskectomy in Treatment of Lumbar Radiculopathy
Approximately 300,000 patients undergo open surgical procedures to treat symptoms caused by disc herniation. Among the various surgical techniques practiced the percutaneous discectomy occupies its space since the first…
- Trial name
- PDOP_TLR (NCT01367860)
- Testing
- Open microdiscectomy, Percutaneous Diskectomy SpineJet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Low Back Pain
Clinical Evaluation of the ReLeaf Analgesic Infusion Catheter & Wound Drain
The purpose of this study is to evaluate the clinical performance of the ReLeaf infusion catheter \& wound drain in patients following lumbar spinal fusion surgery.
- Trial name
- NCT02293525
- Testing
- ReLeaf catheter, Ropivacaine, Saline
- Sponsor
- Vital 5, LLC
Chronic Pain
Efficacy of Yoga Based Self-Management Program for Chronic Pain
Chronic pain is a major health issue with substantial economic burden.To support chronic pain patients during the COVID-19 pandemic, yoga based self-managed intervention was delivered through tele-health platform.
- Trial name
- NCT04628130
- Testing
- Yoga Therapy
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- Aarogyam UK
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Chronic Pain, Musculoskeletal Diseases
Effectiveness of Coping Strategies on the Control of Chronic Non-Cancer Pain and Quality of Life (CNCP_CopQol)
Introduction and objectives: Non-pharmacological interventions in patients with musculoskeletal chronic non-cancer pain (mCNCP) are positioning themselves as an essential pillar in treatment along with pharmacological and…
- Conditions
- Chronic Pain, Musculoskeletal Diseases, Quality of Life, Pain Measurement
- Trial name
- CNCP_CopQol (NCT04696107)
- Testing
- Psychoeducative intervention
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Osteoarthritis
Efficacy of Acupuncture With Physical Therapy for Knee Osteo-Arthritis
This study will examine the efficacy of acupuncture in combination with exercise physical therapy for moderate osteoarthritis (OA) of the knee.
- Trial name
- NCT00035399
- Testing
- Acupuncture
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Old Age
Clinical Study of G Protein Biased Μ - Opioid Receptor Agonist Oliceridine for Optimizing Postoperative Analgesia Under General Anesthesia
Traditional opioid analgesia is a treatment method for moderate to severe pain. However, the use of opioid drugs is not without risks.
- Trial name
- NCT06668298
- Testing
- Oliceridine, Sulfentanil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Neck Pain Musculoskeletal, Neck Pain Treatment
Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief
Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging.
- Conditions
- Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
- Trial name
- NCT06906107
- Testing
- Cervical Manipulation, Exercise, Mobilization
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Baylor University
Degenerative Disc Disease
AMG0103 in Subjects With Chronic Discogenic Lumbar Back Pain
This clinical trial evaluate the safety, tolerability and exploratory efficacy of targeted single injection of AMG0103 in subject with chronic discogenic lumbar back pain
- Trial name
- NCT03263611
- Testing
- AMG0103
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- AnGes, Inc.
Acute Pain
IV Acetaminophen as Adjuvant Analgesic to Hydromorphone - Emergency Department Patients
The goal of this randomized clinical trial is to compare the analgesic efficacy and side effect profile of IV acetaminophen as an analgesic adjunctive medication to IV hydromorphone for the treatment of acute pain experienced by…
- Trial name
- NCT03553498
- Testing
- IV acetaminophen, hydromorphone
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Albert Einstein College of Medicine
Disc Herniation
Effects of Spinal Mobilization With and Without Clinical Pilates in Patients With Lumbar Disc Herniationc Herniation
Lumbar disc herniation is described by The North American Spine Society (NASS) as the confined movement of the disc material like nucleus pulposus and annulus fibrosis outside the limitations of the intervertebral disc space…
- Trial name
- NCT07912047
- Testing
- SPINAL MOBILIZATION, SPINAL MOBILIZATION + CLINICAL PILATES
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Management and Technology Lahore
Barrett Esophagus, Gastroesophageal Reflux
Demographics and Findings of Upper Endoscopy Patients
The purpose of this study is to evaluate the demographics, patients symptoms, and findings during endoscopy. Patients presenting for an endoscopy procedure to the KCVA GI endoscopy suite, will be asked to fill out questionnaires…
- Trial name
- NCT00576992
- Where
- United States
- Volunteers
- 1,177 people, healthy volunteers welcome
- Sponsor
- Midwest Biomedical Research
Chronic Pain
Virtual Reality in Inpatients
This study is being conducted as a pilot to test the feasibility, usability, acceptability, and clinical utility of using a virtual reality (VR) immersion experience in the inpatient setting.
- Trial name
- NCT02456987
- Testing
- Samsung Gear
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Chronic Sacroiliac Joint Pain
Cryoneurolysis vs Radiofrequency Ablation for Chronic Sacroiliac Joint Pain
This is a single-center, randomized, open-label, pilot study in adult subjects with chronic sacroiliac joint (SIJ) pain. Thirty (30) subjects are planned for initial enrollment and will be randomized 1:1 to receive ioveraº…
- Trial name
- NCT06935539
- Testing
- Cryoneurolysis, Radiofrequency ablation
- Volunteers
- 30 people
- Sponsor
- Medical Pain Management Services, PLLC
Coronary Artery Disease, Chest Pain
Imaging Studies With GE C-Hawk Gamma Camera Compared to Routine Clinical Exam
Comparison study of myocardial perfusion SPECT imaging with current clinical use camera and new camera.
- Trial name
- NCT00256581
- Testing
- Additional rest and stress image sets on new camera
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Wisconsin, Madison
Small Fiber Neuropathy, Diabetic Neuropathies
Diabetic Small Fiber Neuropathy: Clinical, Electrophysiological and Neurosonographic Study
The aim of work is to study the clinical, electrodiagnostic and neurosonographic characteristics of diabetic patients with small fiber neuropathy in the Egyptian population, and to evaluate both the diagnostic and the prognostic…
- Conditions
- Small Fiber Neuropathy, Diabetic Neuropathies, Autonomic Neuropathy, Diabetic Peripheral Neuropathy
- Trial name
- NCT05993871
- Testing
- Clinical Evaluation/Questionnaires, Nerve Conduction Study, Small fiber electrodiagnostic tests
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tanta University
Pain
Comparing Articaine and Mepivacaine Without Palatal Injection in Pain Assessment During Maxillary Teeth Extraction
This study compares the the efficacy of buccal infiltration of 4% Articaine and 2% Mepivacaine without any palatal injection during extraction of maxillary teeth.
- Trial name
- NCT03470532
- Testing
- buccal infiltration of 4% Articaine with Epinephrine, buccal infiltration of 2% Mepivacaine with Epinephrine
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
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