Clinical trials: Clinical Pain
Interstitial Cystitis
A Pilot Clinical Investigation of the Efficacy and Safety of Uracyst® Versus Placebo in Patients With Interstitial Cystitis/Painful Bladder Syndrome.
This is a pilot clinical investigation. Patients who meet the eligibility criteria and provide signed informed consent will be randomized to receive either an active product (Uracyst®) or placebo intravesically via a bladder…
- Trial name
- NCT00527917
- Testing
- Uracyst
- Where
- 13 sites in Canada
- Volunteers
- 65 people
- Sponsor
- Watson Pharmaceuticals
Low Back Pain
Recurrent Low Back Pain:Linking Mechanisms to Outcomes
The purpose of this study is to determine if trunk neuromuscular control strategies are changed by therapeutic exercises emphasizing core stabilization.
- Trial name
- NCT01085604
- Testing
- Core Stabilization
- Where
- 2 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Drexel University
Mild Traumatic Brain Injury
Efficacy of Multidimensional Management of Mild Traumatic Brain Injury
Unfavorable outcomes (UO) are seen in 15 to 20% of patients with mild traumatic brain injury (mTBI). Early identification of patients at risk for UO is crucial for suitable management to be initiated, increasing their chances for…
- Trial name
- NCT03811626
- Testing
- cognitive-behavioral rehabilitation
- Where
- 6 sites in France
- Volunteers
- 221 people
- Sponsor
- Institut de Recherche sur la Moelle épinière et l'Encéphale
Pain, Postpartum Depression
Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term.
- Trial name
- NCT03470675
- Testing
- Epidural saline + IV saline, Epidural morphine 3 mg + IV saline, Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Northwestern University
Knee Injuries and Disorders
AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation
The AIR2 Study is a multi-center, prospective, interventional clinical trial with the objective to evaluate the safety and performance of the Trammpolin® medial meniscus prosthesis.
- Trial name
- AIR2 (NCT05297175)
- Testing
- Trammpolin medial meniscus prosthesis
- Where
- 3 sites in Netherlands
- Volunteers
- 10 people
- Sponsor
- ATRO Medical B.V.
Massive Rotator Cuff Tears, Rotator Cuff Injuries
Irreparable Rotator Cuff Tears Treatment. Comparison of Two Methods: With and Without Biceps Tendon Augmentation
Management of massive rotator cuff tears (MRCT) is associated with high rates of failure. The long head of the biceps tendon augmentation (LHBTA) by reinforcement of the reconstruction and additional blood supply may improve…
- Conditions
- Massive Rotator Cuff Tears, Rotator Cuff Injuries, Shoulder Pain Chronic
- Trial name
- NCT05001581
- Testing
- Arthroscopic partial repair of massive rotator cuff tear, Arthroscopic partial repair of rotator cuff with biceps augmentation
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Saint Lucas Hospital, Poland
Pregnancy Complications
Effect of Direct Myofascial Release Technique Combined With Exercise on Round Ligament Pain During Pregnancy
Study's objective is to explore effect of combining direct myofascial release technique with therapeutic exercises on decreasing round ligament pain during pregnancy.The main question to be answered by this study: Does a…
- Trial name
- NCT07715422
- Testing
- Manual therapy technique named myofascial release combined with therapeutic exercises
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Beni-Suef University
Dental Pain, Endodontically Treated Teeth
XP-Endo Finisher on Postoperative Pain in Retreatment Cases Using Mtwo R Files
Introduction: Postoperative pain is one of the most critical issues in our daily practice. , postoperative pain control is essential for patient satisfaction and comfort.
- Trial name
- NCT06625853
- Testing
- Mtwo R files with Xp-Endo finisher file, Mtwo R files
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hams Hamed Abdelrahman
Intervertebral Disc Degeneration, Chronic Low-back Pain
Efficacy of Intradiscal Injection of Autologous BM-MSC in Subjects With Chronic LBP Due to Multilevel Lumbar IDD
DREAM is a phase II B efficacy monocentric, prospective, randomized, controlled double blinded trial, comparing intra-discal autologous adult bone marrow mesenchymal stem cells (BM-MSC) therapy and sham treated controls in…
- Trial name
- DREAM (NCT05066334)
- Testing
- Autologous BM-MSC
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Cervical Disease
Effectiveness of a Home-based Cervical Motor Control Exercise Programme Versus Conventional Manual Therapy in Patients With Post-whiplash Neck Pain.
Whiplash-associated disorders are a common cause of persistent neck pain following traffic accidents and are frequently associated with impairments in cervical motor control, pain, and functional disability.
- Trial name
- NCT07324811
- Testing
- home-based cervical motor control exercise programme, conventional physiotherapy treatment
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Pontificia de Salamanca
Femoro Acetabular Impingement, Hip Pain
Ultrasound-guided Needle Percutaneous Electrolysis With Therapeutic Exercise in Femoroacetabular Impingement Syndrome
Hip pain in the front of the hip is common and can make daily activities and sports difficult. One frequent cause is femoroacetabular impingement, also known as hip impingement.
- Conditions
- Femoro Acetabular Impingement, Hip Pain, Iliopsoas Syndrome, Groin Pain
- Trial name
- NCT07548034
- Testing
- Ultrasound-guided percutaneous needle electrolysis, Therapeutic exercise program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- CEU San Pablo University
Leg Length Inequality, Foot Deformities
Botox Clinical Trial
The surgery to correct leg \& foot deformities in children is a lengthy, \& sometimes, difficult procedure. Metal frames are attached to the leg and / or foot and over a period of time the frame is manipulated to obtain the…
- Trial name
- NCT00624299
- Testing
- Botox, Saline
- Where
- United Kingdom
- Sponsor
- Sheffield Children's NHS Foundation Trust
Root Canal Treatment, Postoperative Pain
Different Kinematics Within a Single-File System and Postoperative Pain
The goal of this clinical trial is to evaluating the influence of single file rotary system for root canal instrumentation using different kinematics on postoperative pain, the primary purpose: measuring post-operative pain by…
- Conditions
- Root Canal Treatment, Postoperative Pain, Apical Periodontitis
- Trial name
- NCT07699432
- Testing
- Twisted Adaptive motion (TFA), canal pro jeni, forward reciprocation
- Where
- Jordan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Acute Lower Back Pain
Comparative Clinical Trial: Manual Therapy With and Without Radial Extracorporeal Shockwave Therapy to Treat Acute Low Back Pain
The goal of this clinical trial is to learn if the addition of radial pulse therapy to chiropractic care will help adult patients recover faster to an acute bout of low back pain.
- Trial name
- NCT06852898
- Testing
- Chiropractic Care, Radial Extracorporeal Shockwave Therapy (ESWT) - Radial Pulse Therapy
- Where
- United States
- Sponsor
- Northeast College of Health Sciences
Acute Myeloid Leukemia, Stem Cell Leukemia
Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients
Evaluation of safety and efficacy of Nalbuphine versus Morphine patient controlled analgesia (PCA) for mucositis pain in pediatric cancer patients
- Trial name
- PCA (NCT03825887)
- Testing
- Nalbuphine, Morphine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Impacted Mandibular Third Molar Extraction
Piezo-surgery Technique and Intramuscular Dexamethasone Injection to Reduce Postoperative Pain After Impacted Mandibular Third Molar Surgery
The purpose of my study is to test the effect of using piezosurgery and dexamethasone injection in the surgical extraction of impacted mandibular third molars, on Postoperative Pain.
- Trial name
- NCT04889781
- Testing
- Dexamethasone injection, Piezosurgery, Conventional Rotatory instruments
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Central Military Healthcare - Oral and Maxillofacial Surgery Department
Angina, Stable
Acupuncture in Patients With Stable Angina Pectoris
This trail aims to evaluate the efficacy of acupoints on the specific meridian for chronic stable angina pectoris, compared with acupoints on the other meridian, sham acupoints and waiting-list.
- Trial name
- ASAP (NCT01686230)
- Testing
- acupuncture, Basic treatment
- Where
- China
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Erosive and Atrophic Oral Lichen Planus
Cedar Honey in Oral Lichen Planus
The study aimed to evaluate the effect of cedar honey in treatment of erosive and atrophic oral lichen planus ( a common oral problem).
- Trial name
- NCT01974414
- Testing
- orally administered cedar honey
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Mashhad University of Medical Sciences
GERD, EPS
Efficacy and Safety Evaluation of Neobianacid® in GERD and EPS
Comparison of Neobianacid® clinical efficacy to omeprazole in relief of heartburn or epigastric pain
- Trial name
- NCT03238534
- Testing
- Neobianacid®, Omeprazole 20mg
- Where
- 12 sites in Italy
- Volunteers
- 275 people
- Sponsor
- Aboca Spa Societa' Agricola
Pain, Neuropathic
Efficacy of Median Nerve Hydrodissection by Hyalase Versus Midazolam in the Treatment of Carpal Tunnel Syndrome:
Comparing efficacy of hyalase and midazolam in median nerve entrapement neuropathy
- Trial name
- NCT05344495
- Testing
- hyalase group, midazolam group
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University
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