Clinical trials: Clinical Practice
Hepatitis C, Hepatitis C, Chronic
Relapse Rate in Hepatitis C Patients Treated With Peginterferon Alfa-2b Plus Ribavirin in Common Clinical Practice in France (P05484)(Completed)
The objective of this study is to determine the relapse rate in the French patient population with chronic hepatitis C (CHC) previously treated with PegInterferon Alfa-2b (Peg-IFN alfa-2b) plus Ribavirin according to standard…
- Trial name
- RE-CHUT (NCT00725842)
- Testing
- Peg-IFN alfa-2b, Ribavirin
- Volunteers
- 97 people
- Sponsor
- Merck Sharp & Dohme LLC
Pertrochanteric Fracture of Femur, Intertrochanteric Fracture of Femur
Retrospective Study Chimaera Long Nail in Adult Patient
The CHIMERA study intends to evaluate the clinical benefits of the study medical device in the standard clinical practice.
- Conditions
- Pertrochanteric Fracture of Femur, Intertrochanteric Fracture of Femur, Subtrochanteric Fracture of Femur
- Trial name
- NCT06285981
- Testing
- Chimaera Long Nail
- Where
- 2 sites in Italy
- Volunteers
- 44 people
- Sponsor
- Orthofix s.r.l.
Anesthesia, General
Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Required General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on Cardiovascular System in Common Clinical Practice
The main objective of this post-marketing observational study is to collect data from the use of general anesthesia in patients undergoing any surgery to create local recommendations.
- Trial name
- SEVOPROTECTION (NCT01282203)
- Where
- 12 sites in Kazakhstan
- Volunteers
- 1,122 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Breast Cancer
Positron Emission Mammography (PEM) Biopsy Accessory for the Diagnosis of Breast Cancer
The purpose of this research study is to evaluate how well the Stereo Navigator Biopsy Accessory for the PEM Flex solo II PET Scanner works for performing breast biopsy on suspicious lesions.
- Trial name
- NCT00981812
- Testing
- PEM Breast Biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Rheumatoid Arthritis
A Study of Glucocorticoid Use to Evaluate Systematic Methylprednisolone Reduction in Patients With Rheumatoid Arthritis on Background RoActemra/Actemra (Tocilizumab) (ACT-ALONE)
This open-label, single-arm study will assess the use of glucocorticoids (GC) in daily clinical practice and will evaluate the dose reduction of glucocorticoids once low disease activity is achieved in patients with rheumatoid…
- Trial name
- NCT01219933
- Testing
- methylprednisolone, tocilizumab [RoActemra/Actemra]
- Where
- 16 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Hoffmann-La Roche
Gastroesophageal Reflux Disease (GERD)
Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF Study
The purpose of this retrospective, open-label, post-market study is to evaluate the safety and efficacy of Transoral Incisionless Fundoplication (TIF) performed with EsophyX (brand name) in a broad range of GastroEsophageal…
- Trial name
- RetroTIF (NCT01327963)
- Testing
- Transoral Incisionless Fundoplication
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- EndoGastric Solutions
Arthritis,Rheumatoid
Long Term Effects of an Early Response to Certolizumab Pegol (CZP, Cimzia®) in Rheumatoid Arthritis (RA) Patients
To determine if early clinical response at 12 weeks to Certolizumab Pegol (CZP, Cimzia ®) therapy in adult Rheumatoid Arthritis (RA) patients is a predictor of better long term clinical response at 18 months compared with a lack…
- Trial name
- RA-PROACTIVE (NCT01288287)
- Where
- 22 sites in Ireland, United Kingdom
- Volunteers
- 149 people
- Sponsor
- UCB Pharma
Dental Caries
Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study
A comparison of caries detection rates between conventional intraoral bitewing radiography and a stationary intraoral digital tomosynthesis (s-IOT) using a carbon nanotube X-ray source array.
- Trial name
- NCT02873585
- Testing
- Stationary intraoral tomosynthesis, Standard conventional bitewing radiography
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Pregnancy Weight Gain, Postpartum Weight Retention
Pragmatic Randomized Clinical Trial to Limit Weight Gain in Pregnancy and Prevent Obesity
Healthy for Two, Healthy for You (H42/H4U) is an innovative evidence-based pregnancy/postpartum health coach intervention that is remotely-delivered (phone coaching using motivational interviewing, web-based platform, mobile…
- Conditions
- Pregnancy Weight Gain, Postpartum Weight Retention, Childhood Obesity, Gestational Diabetes
- Trial name
- H42/H4U (NCT04724330)
- Testing
- Healthy for Two/Healthy for You
- Where
- United States
- Volunteers
- 534 people
- Sponsor
- Johns Hopkins University
Anemia
An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Anemic Patients With Chronic Kidney Disease (NORM)
This observational, prospective, multi-centre, single-arm study will evaluate the efficacy of Mircera (methoxy polyethylene glycol-epoetin beta) in patients with chronic kidney disease previously on treatment with short-acting…
- Trial name
- NCT01417377
- Testing
- Mircera
- Where
- 6 sites in Pakistan
- Volunteers
- 22 people
- Sponsor
- Hoffmann-La Roche
Breast Augmentation
European New Texture Implant Clinical Experience With Round Breast Implants
The purpose of this study is to obtain clinical experience with the use of new texture, round breast implants in bilateral primary breast augmentation.
- Trial name
- NCT01639742
- Testing
- New texture round breast implants
- Where
- 4 sites in Germany, Sweden and 1 more
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Allergan
Infertility
Clinical Performance and Safety Investigation of ENDOmetrial Washing MEdical DEvice Forielle
This is a multicenter, prospective randomized controlled, interventional investigation to assess the safety and clinical performance of Forielle, a medical device for endometrial washing, in restoring favorable endometrial…
- Trial name
- ENDOMEDE (NCT03387059)
- Testing
- Forielle
- Where
- 7 sites in Italy
- Volunteers
- 9 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Kidney Calculi
Initial Clinical Experience With the MONARCH Platform, Urology for the Treatment of Kidney Stones
The purpose of this study is to collect descriptive performance data using the MONARCH Platform, Urology (a novel robotic device) to perform mini-percutaneous nephrolithotomy (kidney stone removal) procedures.
- Trial name
- NCT05835323
- Testing
- Robotic-assisted mini-PCNL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Auris Health, Inc.
Venipuncture, Healthy Adult
Clinical Trial to Assess the Effectiveness of Applying Dry Local Heat and/ or High Tourniquet Pressure for Venipuncture.
Low level intervention health products clinical trial, fourth phase, non-commercial research. Dissertation of COMPLUTENSE UNIVERSITY of Madrid. Principal Investigator of this clinical trial: Ms.
- Trial name
- ECYPVEN-H/17 (NCT04027218)
- Testing
- Dry heat, High pressure, Combination of dry heat and high pressure
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Diabetes Mellitus, Type 2
Non-Interventional Study of the Use of Alogliptin and Alogliptin Fixed-Dose Combinations With Pioglitazone and With Metformin in Standard Clinical Practice
The purpose of this study is to observe alogliptin and alogliptin fixed-dose combinations (FDCs) utilization patterns, as well as clinical response to treatment with alogliptin or alogliptin FDCs, in standard clinical practice.
- Trial name
- NCT02989649
- Testing
- Alogliptin, Alogliptin FDC With Pioglitazone, Alogliptin FDC With Metformin
- Where
- 11 sites in China, Hong Kong
- Volunteers
- 593 people
- Sponsor
- Takeda
Arm Spasticity
Comparing Lower-concentration Dysport Treatment Targeted to the Neuromuscular Junction With Current Clinical Practice
The aim of the study was to compare Dysport treatment results (as assessed by Modified Ashworth Scale (MAS) in the elbow joint 4 weeks post treatment) following two treatment techniques: the current clinical practice injection…
- Trial name
- NMJ (NCT01682148)
- Testing
- Botulinum toxin type A
- Where
- 23 sites in Denmark, Finland and 2 more
- Volunteers
- 100 people
- Sponsor
- Ipsen
Rheumatoid Arthritis
Study With Etanercept Focusing on Remission and Predictability of Remission in Real Life Clinical Practice
Defining Which Remission Criterion at Month 6 Predicts Remission at Month 12 in a Real Life Clinical Practice, in a Cohort of Rheumatoid Arthritis Patients Treated with Etanercept
- Trial name
- REACH RA (NCT02202837)
- Testing
- etanercept
- Where
- 35 sites in Belgium
- Volunteers
- 157 people
- Sponsor
- Pfizer
Anesthesia, General
Clinical Practice of Inhalation Anesthesia With Sevoflurane in China
Until recently, there was a lack of understanding and consensus among Chinese anesthesiologists how they should practice general anesthesia with volatile anesthetics, since there was no standard of inhalation practice.
- Trial name
- NCT01715857
- Where
- 36 sites in China
- Volunteers
- 4,100 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Atrial Fibrillation
Integrated Management Program Advancing Community Treatment of Atrial Fibrillation
Research Question: Among community-based patients with AF, does providing an integrated Clinical Decision Support System (CDSS) to providers and patients improve process of care and clinical outcomes, and decrease the healthcare…
- Trial name
- IMPACT-AF (NCT01927367)
- Testing
- Clinical Decision Support System for AF
- Where
- 2 sites in Canada
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- Jafna L Cox
Childhood Obesity
Intervention for the Prevention of Obesity in Preschool
The purpose of this study is to develop, implement and evaluate an intervention focused to change feeding practices and patterns of physical activity of preschool children through providing motivational counseling to the mother.
- Trial name
- NCT01539070
- Testing
- Eating and physical activity counseling
- Where
- Mexico
- Volunteers
- 306 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico