Clinical trials: Cognition - Other
Cognition - Other, Strength Outcomes
Effects of Alpha-GPC on Muscle Power, GH Levels, and Cognitive Function
Purpose: To determine the effects of low dose and high dose Alpha-GPC on cognitive performance, muscle performance, and serum growth hormone levels.
- Trial name
- NCT06690619
- Testing
- 315 mg Alpha-GPC, 630 mg Alpha-GPC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Schizophrenia, Autism Spectrum Disorder
A Computational Neuroscience Perspective on the Shared Social Cognitive Deficits of Autism and Schizophrenia
This retrospective cohort study will examine shared neural mechanisms of social cognitive deficits in adults with autism spectrum disorder and adults with schizophrenia using existing clinical, behavioral, and neuroimaging data…
- Trial name
- NCT07618767
- Where
- Taiwan
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Physiological Stress, Cognition - Other
Effects of Probiotics on Cognition and Health
This research intervention aims to examine the effects of a fermented dairy beverage on changes in behavioral and biological measures of cognition and stress among adults.
- Trial name
- EPOCH (NCT02849275)
- Testing
- Lactose Free 1% Milk, Probiotic Treatment
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Schizophrenia
Modafinil Effects on Cognition in Schizophrenia Patients
Patients with schizophrenia have problems in thinking, known as cognitive dysfunction. This includes many types of cognitive dysfunction, such as in attention, memory and language.
- Trial name
- InO (NCT00711464)
- Testing
- modafinil (M1, M2, M4)
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gastrointestinal Dysfunction, Physiological Stress
NECTAR Study: Nectar (Honey) Effects on Comfort, Thoughts, and Regularity
This study aims to test the central hypothesis that adding to the diet daily yogurt with honey provides beneficial effects on digestive health and subjective mood in healthy adults.
- Conditions
- Gastrointestinal Dysfunction, Physiological Stress, Cognition - Other
- Trial name
- NECTAR (NCT04187950)
- Testing
- Yogurt with B. lactis and added honey, Yogurt with heat-inactivated B. lactis and added cane sugar
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-II (NCT02710097)
- Testing
- Active inhaled cannabis, Active Oral Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Depression - Major Depressive Disorder, Bipolar
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health Trajectories
Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health (BLOOM) is a project that aims to overcome age and diagnostic boundaries to generate person-specific longitudinal profiles of mental…
- Conditions
- Depression - Major Depressive Disorder, Bipolar, Psychosis, Eating Disorder NOS
- Trial name
- BLOOM (NCT06978452)
- Where
- Canada
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH (NCT02404688)
- Testing
- Active delta-9-THC, Active Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia
Different Safety Profile of Risperidone and Paliperidone Extended-release
The main objective of this study was to assess subjective experiences related to secondary negative symptoms and cognitive performance in healthy volunteers in response to multiple doses of paliperidone ER and risperidone in a…
- Trial name
- NCT01284959
- Testing
- risperidone, paliperidone ER
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Schizophrenia
Metformin Treatment on Cognitive Impairment of Schizophrenia
In this study, the investigators will investigate the effect and the underlying mechanism of metformin treatment on cognitive impairment in individuals with schizophrenia.
- Trial name
- NCT05838573
- Testing
- Metformin treatment, Baseline assessments, Volunteer assessments
- Where
- 4 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Central South University
First Episode Psychosis (FEP), Psychosis
Early Psychosis: Investigating Cognition
The project aims to explore changes in brain chemistry in individuals who have recently experienced psychosis. Recent research suggests that chemicals in the brain, specifically one called glutamate, may behave differently in…
- Trial name
- EPIC (NCT07196423)
- Testing
- Transcranial direct current stimulation (tDCS), Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Schizophrenia, Quality of Life
Milestones of Adjustment Post-Psychosis
This nested design clinical outcome study of psychiatric case manager education on disease state, psychopharmacology of schizophrenia, relapse, motivational interviewing, and the process of psychological adjustment post-psychosis…
- Conditions
- Schizophrenia, Quality of Life, Adjustment, Psychological, Medication Adherence
- Trial name
- MAPP (NCT01192594)
- Testing
- Training in all modules including MAPP Recovery Model, Training in all modules except MAPP Recovery Model
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia
Social Cognition in Youth Who Have a First Degree Relative With Schizophrenia
Social cognition is an individual's ability to perceive, process, understand, and react to other individuals in a social situation.
- Trial name
- NCT04681807
- Testing
- Emotion Recognition Training, Control Training
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- The Royal Ottawa Mental Health Centre
Schizophrenia, Cognition Disorders
The Effect of Nicotine on Arousal, Cognition and Social Cognition in Young and Elderly Healthy Subjects.
This study in young and elderly healthy subjects will investigate the effect of nicotine on arousal, cognitive task and social cognition after acute dose administration.
- Trial name
- NCT01181934
- Testing
- A643 (nicotine)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Janssen Pharmaceutica N.V., Belgium
Mild Cognitive Impairment, Dementia
Multimodal Imaging in the Study of Disorientation in the Hospital
The purpose of this study is to investigate whether markers of brain structure and function from MRI are associated with different levels of spatial orientation and gait parameters in people with mild cognitive impairment or…
- Conditions
- Mild Cognitive Impairment, Dementia, Disorientation, Older Adults
- Trial name
- NCT04387357
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Medical Center Rostock
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Autistic Disorder
Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
The schizophrenic disorders and pervasive developmental disorders are neurodevelopmental disorders distinct origin who share common challenges to engage and maintain social relationships and mutual disturbances of affective…
- Trial name
- NCT01805128
- Testing
- Facial recognition of emotions, understanding metaphors, Attribution of intentionality to others in social situations depending on the type of situation
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Early-onset Schizophrenia, Psychotic Disorders
Computerized Cognitive Remediation Therapy in Adolescents With a First Psychotic Episode
Cognitive deficits (CD) are considered one of the essential characteristics in psychotic disorders and occur throughout the course of the disease, being a key characteristic in the evolution of the disease and in the…
- Conditions
- Early-onset Schizophrenia, Psychotic Disorders, Cognitive Remediation Therapy, Cognition
- Trial name
- CCRT2019 (NCT05405946)
- Testing
- Computerized Cognitive Remediation Therapy, Treatment as Usual
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Schizophrenia
Pan European Collaboration on Antipsychotic Naive Schizophrenia (PECANS)
The investigators want to relate disturbances in first-episode schizophrenic patients in (dopaminergic) D2 receptors, brain structure, brain function, and information processing to each other and to psychopathology.
- Trial name
- PECANS (NCT01154829)
- Testing
- amisulpride, aripiprazole
- Where
- Denmark
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cognition - Other
Effect of Omega-3 Phospholipids on Perceptual-cognitive Training
Omega 3 in the form of phospholipids are the main component of nerve cells and their oral intake is known to have a positive impact on behavior disorders such as depression or bipolar disorder.
- Trial name
- NCT01856829
- Testing
- Omega-3
- Where
- 2 sites in Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Université de Montréal