Clinical trials: Cognitive/Functional Effects
Multiple Sclerosis, Relapsing-Remitting
Examining Effects of Tysabri on Cognitive Fatigue Using fMRI
The purpose of this research study is to investigate the effectiveness of Tysabri on cognitive fatigue in persons with Relapsing-Remitting Multiple Sclerosis (RRMS).
- Trial name
- NCT04565431
- Testing
- Tysabri
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Healthy Nutrition, Pregnancy Related
Maternal Carotenoids Across Pregnancy Study
Before infants are born, they depend on their mother to provide the nutrients necessary to grow and develop, such as iron, folic acid, iodine and other vitamins and minerals.
- Trial name
- MCAPS (NCT06004479)
- Testing
- Carotenoid Intake, Serum carotenoid concentration
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Irisin, Lactate
Effects of Different Types of Exercise on Irisin and Cognitive Performance (Exercise-Irisin)
Purpose The purpose of this study was to determine the acute effects of different exercise intensities on Irisin levels, trail making test performance, and feeling scale.
- Conditions
- Irisin, Lactate, Cognitive Function, Exercise Training
- Trial name
- Ex-Irisin (NCT07146490)
- Testing
- Low Exercise, Long Interval Exercise, Short Intevral Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Alteration of Cognitive Function
Cognitive Effects of Tai Chi Chuan in Healthy Older Adults and Older Adults
Background: Promotion of cognitive functions of middle aged and older adults and prevention of dementia are important issues in the aging society.
- Trial name
- NCT02270320
- Testing
- Physical activity
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Decline
Investigate the Effect of Tart Montmorency Cherry Juice (Prunus Cerasus) on Cerebral Blood Flow and Cognitive Function
Scientific studies in humans suggest that diets high in fruit and vegetables may be able to improve some aspects of mental performance such as improving memory and reaction times.
- Trial name
- NCT02381860
- Testing
- 60mL tart Montmorency cherry juice
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Thyroid, Carotid Doppler
Effect of Head Position During Thyroidectomy on Postoperative Cognitive Functions
The aim of our study is to observe the effect of head-neck position of patients scheduled for thyroidectomy, on carotid artery blood flow, regional cerebral oxygen saturation measured using near-infrared spectroscopy technology…
- Conditions
- Thyroid, Carotid Doppler, Cerebral Perfusion
- Trial name
- NCT04830293
- Testing
- Carotis Doppler Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Healthy Adults.
Investigating the Acute Effects of Flavonoids in Blueberries on Cognitive Function.
This study was a controlled, cross-over, acute flavonoid intervention trial with younger and older adults. Subjects consumed a blueberry beverage during one visit and a control beverage on another.
- Trial name
- NCT01289860
- Testing
- Flavonoids, Control
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Reading
School Readiness, Executive Function (Cognition)
Playful Physical Activity for Executive Functions and School Readiness in Preschool Children
Executive functions, such as attention, inhibition, working memory, and planning, are important for early learning and school readiness in preschool children.
- Conditions
- School Readiness, Executive Function (Cognition), Preschool Child Development
- Trial name
- PPA-EF-SR (NCT07678294)
- Testing
- Playful Physical Activities Intervention, Regular Physical Education Curriculum
- Where
- Tunisia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anxiety Symptoms
Effect of IATP on Cognitive Functioning in Anxious Older Adults.
Older adults with anxiety symptoms was found to be associated with greater risk of dementia. Interventions targeting signs as early as in the pre-symptomatic phase could be most effective in early prevention of dementia.
- Trial name
- NCT04413513
- Testing
- Integrated Attention Training Program (IATP), Health Education
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Aging
Effect of mTOR Inhibition and Other Metabolism Modulating Interventions on the Elderly
The ability to mount an effective immune response declines with age, leaving the elderly increasingly susceptible to infectious diseases and cancer.
- Trial name
- NCT02874924
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Brain Vascular Function, Cognitive Function
Effects of Protein Supplementation on Brain Function
Protein-rich foods may improve brain insulin-sensitivity, which is important for cognitive and metabolic health, and may also translate into an improved food intake regulation.
- Conditions
- Brain Vascular Function, Cognitive Function, Satiety, Cerebral Blood Flow
- Trial name
- NCT07057245
- Testing
- Protein supplementation with an animal-based protein isolate, Protein supplementation with a plant-based protein isolate, Control arm - cornstarch
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Smoke Exposure, Smokeless Tobacco
Effect of Passive Smoking on Functional Capacity, Cognition and Academic Performance in Primary School Children
This is an observational study that aims to understand the effects of passive smoking (secondhand smoke exposure) on children's health and development.
- Trial name
- NCT06723470
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Egyptian Chinese University
Obesity, Cognitive Ability, General
Physical Activity and Intermittent Exercise Training for Cardiovascular and Cognitive Gain in Obese Women
One hundred participants from a combination of (a) local advertisements and/or (b) those whose details are held on a research database (of previous volunteers indicating willingness to be contacted about future studies) will be…
- Conditions
- Obesity, Cognitive Ability, General, Cardiovascular Disease
- Trial name
- NCT02853279
- Testing
- Interval exercise training, Continuous exercise training (CON)
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Neurodegeneration
Effects of Flavonoids on Cognitive Performance in Healthy Young Adults
The purpose of this study is to investigate changes in cerebral blood flow, blood flavonoid levels, brain-derived neurotrophic factor, vascular reactivity and cognitive performance in young adults as a result of acute…
- Trial name
- NCT01312597
- Testing
- Fruit juice beverage
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Resistance Exercise Performance, Cognitive Functions
Dose-Response Effects of Short-Term Ashwagandha on Anaerobic Exercise and Cognitive Function in Resistance-Trained Athletes
Ashwagandha (ASH) is an herbal supplement derived from the Withania somnifera plant. It is commonly described as an adaptogen, a substance thought to help the body cope with physical and psychological stress.
- Conditions
- Resistance Exercise Performance, Cognitive Functions, Anaerobic Performance, Dietary Supplementation Athletic Performance
- Trial name
- ASH (NCT07853274)
- Testing
- Low-dose Ashwagandha Supplement, High-dose Ashwagandha Supplement
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Jacksonville State University
Schizophrenia Disorders, Cognitive Dysfunction
Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation
This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia.
- Conditions
- Schizophrenia Disorders, Cognitive Dysfunction, Emotion Regulation Disorders
- Trial name
- CRT-SCHZ (NCT06936397)
- Testing
- Cognitive Remediation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Sedentary Behavior, Light Intensity Physical Activity
The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively.
- Trial name
- NCT04716582
- Testing
- Sitting interrupted by light physical activity, Sitting with cognitive task, uninterrupted sitting
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Cognitive Performance, Attention
Effects of Caffeine on Chess Performance and Cognitive Function in Professional Chess Players
This study will examine whether caffeine improves cognitive and competitive performance in professional chess players during tournament-style games.
- Conditions
- Cognitive Performance, Attention, Reaction Time, Caffeine
- Trial name
- GRANDMASTER (NCT07641335)
- Testing
- Caffeinated Coffee
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Mild Cognitive Impairment, Alzheimer Disease
Effects of Yeast Beta-glucan on Cognitive Function in Patients With Mild Cognitive Impairment
Patients with mild cognitive impairment aged 50-80 years old were recruited in Shiyan City, Hubei Province, and divided into intervention group and placebo group.
- Trial name
- NCT06083350
- Testing
- Yeast beta-glucan, Starch
- Where
- 2 sites in China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Xiaofan Xu