Clinical trials: Cognitive/Functional Effects
Atopic Dermatitis
The Effect of Intervention and Mechanism of ICBT on Chronic Itching in Patients With Atopic Dermatitis
Objectives: The study subjects were 180 healthy people from the dermatology clinic of Xiangya Hospital of Central South University and the surroundingcommunity, including 120 AD patients (60 in the ICBT treatment group and 60 in…
- Trial name
- NCT05502848
- Testing
- Internet Cognitive Behavior Therapy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Healthy
Diet and the Aging Brain
We investigate whether a change in diet could provide positive effects on general brain functions in healthy elderly people.
- Trial name
- NCT00463255
- Testing
- diet
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Atherosclerosis, Vascular Disease
The Effect of Folic Acid on Atherosclerosis, Cognitive Performance and Hearing
The purpose of this study is to determine if folic acid supplementation can slow down atherosclerotic progression, age-related cognitive decline and age-related hearing loss.
- Conditions
- Atherosclerosis, Vascular Disease, Cognitive Decline, Hearing Loss
- Trial name
- NCT00110604
- Testing
- folic acid (0.8 mg)
- Where
- Netherlands
- Volunteers
- 835 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Depression in Chronic Hepatitis C
Effects of Direct-acting Antiviral Agents on HCV Cognitive Function, and Depression in HCV Related Cirrhosis: A Prospective Clinical Trial
Minimal hepatic encephalopathy (MHE) is an important clinical variant of hepatic encephalopathy (HE), which occurs in up to 60-70% of patients with cirrhosis.
- Trial name
- NCT04330508
- Testing
- Depression and Cognitive Tests
- Where
- India
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Primary Insomnia
The Effects of Modafinil on Waking Function and on Sleep in Individuals With Primary Insomnia
This study examines how treatment with the drug modafinil, by itself or in combination with cognitive behavioral treatment for insomnia (CBT-I), may improve daytime functioning and/or diminish the severity of insomnia.
- Trial name
- NCT00124384
- Testing
- CBT-I, modafinil
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Healthy Aging, Motor Learning
The Effect of Tai Chi Chuan in Older Adults
30 healthy older participants were enrolled in the study and were randomly classified into two groups. In the experimental group (n = 15) participants received 10-week Tai Chi Chuan practice intervention, in the control group…
- Conditions
- Healthy Aging, Motor Learning, Cognitive Function
- Trial name
- NCT04690244
- Testing
- Tai Chi Chuan trainings
- Where
- Lithuania
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Schizophrenia, Nicotine Addiction
Effects of rTMS on Cigarette Smoking and Cognition in Schizophrenia
Cigarette smoking rates are extremely high in persons with schizophrenia and this increases the risk of disease and death due to tobacco-related disorders.
- Trial name
- rTMSsmokelab (NCT01523730)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Frailty
Effects of Low-Speed and High-Speed Resistance Training Programs on Frailty Status
The present study refers to a three-arm randomized controlled trial that investigated the effects of two types of RT on frailty status, physical performance, cognitive function, and blood pressure of prefrail and frail older…
- Trial name
- RTF (NCT04868071)
- Testing
- Physical Exercise
- Where
- 2 sites in Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Alzheimer Disease (AD), Dementia Alzheimer Type
Effects on the Olfactory Epithelium and the Olfactory Nerve From Exposure to Diesel Exhaust
The goal of this study is to study the effect exposure to air pollution and its effect on development of dementia. Does the diesel exhaust change the function of the olfactory system? Have the exposures measurable effects on the…
- Conditions
- Alzheimer Disease (AD), Dementia Alzheimer Type, Air Pollution Exposure
- Trial name
- DINOSE (NCT07237958)
- Testing
- Diesel Exhaust Particles, Filtered air
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umeå University
Calorie Deficiency, Fasting
Effects of Calorie Restriction and Cold Stimuli on Health-related Indicators, Cognitive and Motor Functions
The goal of this clinical trial was to identify if duration of acute calorie restriction (CR)/fasting or combination CR with cold stimuli have any effects on mental and physical health-related markers, and to clarify if different…
- Conditions
- Calorie Deficiency, Fasting, Cold Exposure
- Trial name
- NCT05545943
- Testing
- 2-days of zero calorie restriction and whole-body cold-water immersion, 6-days of calorie restriction, 2-days of zero calorie restriction without whole-body cold-water immersion
- Where
- Lithuania
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Physical Performance, Cognitive Function
The Impact of Omega-3 Fatty Acid Supplementation on the Composition of Erythrocyte Membranes in Athletes
The aim of this study is to evaluate the effects of omega-3 fatty acid supplementation on the Omega-3 Index, erythrocyte membrane composition, cognitive function, hormonal profile, speed, endurance performance, and hematological…
- Conditions
- Physical Performance, Cognitive Function, Sports Nutrition
- Trial name
- OMEGA-PERFORM (NCT07768423)
- Testing
- EPA + DHA supplements
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Cognition, Mood
Prevention of the Age-Related Cognitive Impairment by Exercise and Mental Activity - Berlin Bleibt Fit
The trial will evaluate the effects of frequent exercise and increased mental activity on the age-related impairment of cognitive function in elderly women.
- Trial name
- BBF (NCT00629174)
- Testing
- Exercise, Mental activity
- Where
- 2 sites in Germany
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Hydration Status, Sport Performance
Effects of Dehydration on Motor Skills, Attention, and Performance in Adolescent Football Players
This study aims to investigate how hydration status affects attention, motor competence, and football skills in adolescent male football players aged 13-14 years.
- Conditions
- Hydration Status, Sport Performance, Football, Adolescent Athletic Performance
- Trial name
- NCT07320313
- Testing
- Euhydration Protocol, Hypohydration Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- bekir tokay
Cognitive Dysfunction ( MMSE < 24 )
Effects of tDCS on Cognitive Function in Older Adults With Subjective Cognitive Decline: Randomized Sham-Controlled Trial
This randomized, double-blind, sham-controlled clinical trial evaluates the effects of transcranial direct current stimulation (tDCS) using the Sooma Oy device on cognitive function in older adults with Subjective Cognitive…
- Trial name
- TDCSCOGSCDTRIA (NCT07531888)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Mexico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma del Estado de Hidalgo
Parkinson's Disease (PD), Cognition
Effects of Cognitive Dual-Task on Gait in Parkinson's Disease
The aim of this study is to evaluate gait in individuals diagnosed with PD under tasks involving different cognitive domains, to compare the results with those of age and sex-matched healthy individuals, and to determine which…
- Conditions
- Parkinson's Disease (PD), Cognition, Gait Disorders
- Trial name
- NCT07540325
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Aging, Cognitive Performance
Visual Stimulus-Based Cognitive-Motor Agility Exercise in Older Adults
This randomized controlled trial examined the effects of adding a brief visual stimulus-based cognitive-motor agility exercise component to a multicomponent exercise program in community-dwelling older adults.
- Conditions
- Aging, Cognitive Performance, Psychomotor Performance, Exercise
- Trial name
- NCT07714148
- Testing
- Multicomponent Exercise Program, Visual Stimulus-Based Cognitive-Motor Agility Exercise, Time-Matched Low-Intensity Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Nerve Degeneration
Orange Juice Consumption and Cognitive Function
This study is investigating the effect of 8 weeks of orange juice supplementation on executive function in healthy older adults.
- Trial name
- OJOC (NCT01312610)
- Testing
- High flavanone orange juice, Control orange juice
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Listening Effort, Cognitive Function 1, Social
The Effect of Listening Effort, Cognition and Anxiety-depression in Listening Satisfaction by Hearing Aid Users
Brief Summary Introduction: Listening can be effortful in situations that require the intensive use of cognitive processing resources especially for individuals with a hearing loss.
- Conditions
- Listening Effort, Cognitive Function 1, Social, Anxiety, Depression
- Trial name
- NCT05781126
- Testing
- The Spatial Hearing Questionnaire, MINI-MENTAL STATE EXAMINATION, International Outcome Inventory - Hearing Aid, Glasgow Hearing Aid Benefit Profile, BECK-II and STAI questionnaires
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chania General Hospital "St. George"
Cardiometabolic Health, Cognitive Function
The Effect of Oily Fish and Poultry on Children's Cardiometabolic Health and Cognitive Function
The purpose of FiSK Junior is to investigate whether intake of oily fish compared to poultry affects cardiovascular risk markers, cognitive function, and behaviour in healthy children.
- Trial name
- FiSK Junior (NCT02809508)
- Testing
- Oily fish, Poultry
- Where
- Denmark
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Citrulline, Blood Flow
Effect of L-Citrulline on Vascular Function
The objective of this project is to determine the importance of peripheral vascular function on gait performance in older adults.
- Conditions
- Citrulline, Blood Flow, Aging
- Trial name
- NCT03127917
- Testing
- L-citrulline
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Texas Tech University