Clinical trials: Cognitive/Functional Effects
Healthy
Acute Effect of a Standardized Botanical Blend Rich in Polyphenols on Cognitive Functions in Healthy Students
Available literature suggests that flavanols-rich foods, and more especially monomeric flavanols-rich foods such as grape, can have an acute effect on cognitive functions via different mechanisms such as cerebral blood flow…
- Trial name
- NCT03508206
- Testing
- SBRP
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Activ'inside
Executive Functions (EF), Decision Making
Effects of Cognitive Training on Executive Functions and Decision-Making in Adolescent Female Volleyball Players
This randomized controlled trial aims to evaluate the effects of a four-week tablet-based cognitive training program on executive functions and on-court decision-making performance in adolescent female volleyball players.
- Conditions
- Executive Functions (EF), Decision Making, Volleyball
- Trial name
- NCT07692698
- Testing
- Tablet-Based Cognitive Training, Routine Volleyball Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Firat University
Mild Cognitive Impairment
The Effects of Transcranial Direct Current Stimulation in Mild Cognitive Impairment
Objectives: 1) To examine whether the real transcranial direct current stimulation (tDCS) group would perform better in the cognitive training (CT) intervention than the sham tDCS group and the CT group; 2) To determine if, as a…
- Trial name
- NCT03441152
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Dysfunction, Postoperative Complications
The Effect of Hypotensive Anesthesia on Cognitive Functions in Orthognatic Surgery
The purpose of this study is to evaluate the effects of maintaining adequate cerebral oxygen saturation on patients undergoing orthognathic surgery.
- Trial name
- NCT06925711
- Testing
- Near-Infrared Spectroscopy (NIRS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Anxiety
Effect of a Six-week Integrated Attention Training Program on the Cognitive Functions of Older Adults With Co-occurring Anxiety Symptoms and Subjective Cognitive Complaints
The goal of this single-blind randomized control trial is to compare a 6-week Integrated Attention Training Program (IATP) and health education in older people with co-occurrence of anxiety symptoms and subjective cognitive…
- Trial name
- NCT06063265
- Testing
- Integrated Attention Training Program
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Duchenne Muscular Dystrophy
Neuropsychological Profiles of Children With Duchenne Muscular Dystrophy and Its Effects on Motor Functions
This study was planned to determine neuropsychological profiles of children with Duchenne Muscular Dystrophy and investigation of its effects on motor functions \& compare to typically developed peers.
- Trial name
- NCT05661071
- Testing
- Modified Mini Mental Test:, The Controlled Oral Word Association Test, The Central Nervous System Vital Signs
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Aging, Longevity
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life
The LONG-LIFE study is a randomized Phase I, dose-ranging trial designed to evaluate whether psilocybin impacts aging-related biomarkers, cognitive function, and purpose/meaning in life in medically stable older adults.
- Conditions
- Aging, Longevity, Biomarkers of Aging
- Trial name
- LONG-LIFE (NCT07719088)
- Testing
- Psilocybin (Usona Institute)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles Raison
Sedentary Behavior
The Effect of Standing Desks on Cognitive Performance in Adolescents
Sitting or sedentary behavior is associated with several adverse health outcomes such as overweight and obesity, diabetes type 2,... independent of physical activity levels.
- Trial name
- UP4BRAINS (NCT04327414)
- Testing
- Intervention group
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University Ghent
Cognitive Change
Acute Dose-ranging Effects of Mango Leaf Extract (Zynamite® 15%) on Cognitive Function and Cerebral Blood Flow
Zynamite® is a novel mango (Mangifera indica) leaf extract standardized to contain polyphenol mangiferin.It has previously been shown to enhance brain oxygenation, physical performance and ergogenic parameters following…
- Trial name
- NCT05580146
- Testing
- Zynamite® 15% 150mg, Zynamite® 15% 300mg, Zynamite® 15% 600mg
- Where
- United Kingdom
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Diet Modification
Cannabinoid Supplementation on Vascular and Cognitive Function
Cannabidiol (CBD) is a bioactive cannabinoid compound in marijuana (cannabis sativa), but unlike Δ9 tetrahydrocannabinol (THC), lacks the psychoactivity effect of THC.
- Trial name
- NCT03295903
- Testing
- Cannabidiol supplement
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Physical Fitness, Cognitive Function
Effects of a 12-Week Dance Intervention on Physical Fitness and Cognitive Function in Female College Students
This study aimed to examine the effects of a 12-week dance intervention on physical fitness and cognitive function in female college students.
- Trial name
- NCT07769411
- Testing
- 12-Week Dance Intervention, Regular Physical Education
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Jiangsu University of Science and Technology
Healthy Japanese Subjects
Effects of Consumption of Phosphatidylserine on the Cognitive Function
The main objective of this trial is to verify the effects of consumption of phosphatidylserine for 12 weeks on the cognitive function in healthy Japanese subjects.
- Trial name
- NCT05962008
- Testing
- DHAPS® product, BioPS® product
- Where
- 2 sites in Japan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Orthomedico Inc.
Human Volunteers
Effects of Micro-dose and Low-dose Recombinant Human Erythropoietin on Mitochondrial Function and Cognitive Performance
A recent study by Plenge et al. revealed that rhEpo treatment enhances skeletal muscle mitochondrial respiratory capacity in humans indicating a muscle ergogenic effect of rhEpo on aerobic metabolism.
- Trial name
- NCT03093506
- Testing
- Low-dose rhEpo, Micro-dose rhEpo
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Nutritional Status
A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population
This study will examine the impact of creatine supplementation on muscle function and cognitive performance in young and older subjects.
- Trial name
- NCT02058654
- Testing
- Creatine
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cognition - Other, Strength Outcomes
Effects of Alpha-GPC on Muscle Power, GH Levels, and Cognitive Function
Purpose: To determine the effects of low dose and high dose Alpha-GPC on cognitive performance, muscle performance, and serum growth hormone levels.
- Trial name
- NCT06690619
- Testing
- 315 mg Alpha-GPC, 630 mg Alpha-GPC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Hamstring Muscles, Muscle Function
Effect of Exercises on Hamstring Muscle Function, Injury Risk, Agility and Cognitive Function
Hamstring muscle injuries (HMI) occurs frequently during excessive motions of the physiologic capability of these muscles. It is reported in the literature that impairments in muscle architecture, such as a decrease in the…
- Conditions
- Hamstring Muscles, Muscle Function, Cognitive Function, Turkish Get Up
- Trial name
- NCT04563611
- Testing
- Turkish Get-up exercise, Askling L-Protocol, Nordic hamstring exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Diabetes Mellitus, Hypoglycemia
Hypoglycemia Counterregulation and Symptom Perception With Insulin Detemir
Hypoglycemia and unawareness of hypoglycemia are major problems of insulin therapy in patients with diabetes mellitus. The long acting insulin analogue Detemir has structural and physicochemical properties which differ from human…
- Trial name
- NCT00490893
- Testing
- Detemir
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
No Disease or Condition is Being Studied, The Aim: to Determine the Impact of a 25-minute Nap on Cognitive Function
The Effect of a Nap Protocol on the Cognitive Abilities of Experienced Teachers
This protocol aims to investigate the effects of a 25-minute nap on various cognitive variables, such as, simple and selective reaction time, stress and the detection and management of disruptive behaviors during instructional…
- Trial name
- NCT07655167
- Testing
- the nap routine
- Where
- Tunisia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Higher Institute of Sport and Physical Education, Ksar-Said
Cognitive Function, Cognitive Performance
A Clinical Trial to Evaluate the Effects of Two Supplements on Cognitive Function, Cognitive Performance, and Mood
This study evaluates the effects of two liquid dietary supplements, BrainJuice Peach Mango (test product one) and BrainJuice ACTIVE Pomegranate Acai (test product two), on cognitive function, cognitive performance, and mood in…
- Conditions
- Cognitive Function, Cognitive Performance, Mood
- Trial name
- NCT07766564
- Testing
- BrainJuice Supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BrainJuice
Acute Pain, Respiration
Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers
The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model.
- Conditions
- Acute Pain, Respiration, Sedation
- Trial name
- Remiclon (NCT00730054)
- Testing
- Remifentanil+clonidine
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital