Clinical trials: Cognitive/Functional Effects
Cognitive Function, Hypertension
Effects of Different Types of Exercise on Cognitive Function in Postmenopausal Hypertensive Women
Brief Summary: The study was conducted in two parts, the first of which was carried out using a cross-sectional design approach to explore the relationship between cognitive function and autonomic function, brain function…
- Trial name
- NCT05898503
- Testing
- Walking exercise + resistance training, Resistance training, Walking exercise
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain Vascular Function, Cerebral Blood Flow
Mixed Nuts and Brain Vascular Function
Impaired brain vascular function precedes the development of reduced cognitive performance, while brain insulin-resistance is also associated with cognitive decline.
- Trial name
- NCT04210869
- Testing
- Mixed Nuts
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Alteration of Cognitive Function
Physiologic Effects of Topiramate on Cognition
Data generated from this pilot project will be used to support a larger, NIH funded study to investigate the physiologic mechanisms associated with the cognitive side effects of a commonly prescribed antiepileptic drug (AED)…
- Trial name
- NCT02884050
- Testing
- Topiramate
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 1 Diabetes Mellitus, Hypoglycemia Unawareness
The Role of Endogenous Lactate in Brain Preservation and Counterregulatory Defenses Against Hypoglycemia
Iatrogenic hypoglycemia is the most frequent acute complication of insulin therapy in people with type 1 diabetes (T1DM). Recurrent hypoglycemic events initiate a process of habituation, characterized by suppression of…
- Trial name
- NCT02308293
- Testing
- High intensity exercise, Lay down comfortably
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Attention, Mood
A Study to Assess the Synergistic Effects of a Cranberry Beverage on Cognitive Function
This study aims to determine the effect short-term dosing (7 days) of a placebo beverage, cranberry juice, cranberry juice + lemon balm extract, cranberry juice + tart cherry powder, or cranberry juice + L-theanine or L-theanine…
- Trial name
- NCT05008549
- Testing
- Cranberry Juice Product
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ocean Spray Cranberries, Inc.
Social Isolation, SCD
The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)
The goal of this clinical trial is to learn about the effects of social isolation and social interaction on the risk of dementia progression and brain function in SCD 1.
- Conditions
- Social Isolation, SCD, Subjective Cognitive Decline, MCI
- Trial name
- NCT06335836
- Testing
- social isolation
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Accidental Falls, Aging
Evaluation of the Effects of a Cognitive-Motor Fall Prevention Program on Fall Risk Factors
The goal of this interventional study is to compare in community dwelling elderly people the effects of two physical activity programs to prevent accident falls : "SILVER XIII EQUILIBRE" program and "VIVIFRAIL" program, on…
- Conditions
- Accidental Falls, Aging, Mild Cognitive Impairment
- Trial name
- 13EVAL (NCT05625828)
- Testing
- Cognitive-motor Physical Activity, Multifactorial Physical Activity
- Where
- France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Healthy
The Effect of Probiotic Supplementation on Cognitive and Emotional Functions in Healthy Elderly Subjects
This study evaluates the cognitive and emotional effects of probiotics in healthy elderly patients.
- Trial name
- NCT04828421
- Testing
- Lactobacillus rhamnosus and Bifidobacterium lactis
- Where
- 3 sites in Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Dementia, Alzheimer Disease
Effects of Remote-based Resistance Training on Cardiometabolic Risk Factors, Cognitive Function, and Quality of Life in Adults Living With Alzheimer's Disease and/or Related Dementias
The investigators aim to study the effects of a 24-week remote-based resistance exercise training program on cardiovascular disease risk factors, cognitive function, and quality of life in older adults living with mild cognitive…
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Lewy Body Disease
- Trial name
- NCT05004558
- Testing
- Remote-based Resistance Exercise Training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Drexel University
Glucose Intolerance, Energy Expenditure
Effects of Acute Sleep Deprivation on Health
This study will investigate whether various types of regular exercise can provide protective effects against metabolic abnormalities induced by sleep restriction.
- Conditions
- Glucose Intolerance, Energy Expenditure, Vascular Stiffness, Cognition
- Trial name
- NCT07403864
- Testing
- Normal sleep, Partial sleep deprivation
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
General Health and Wellness, Energy and Vitality
M4C Nutraceutical Intervention Human Health Effects Pilot
This 3 month pilot study will be an unblinded, convenience sampling, nutraceutical intervention trial. Twenty fasted subjects will undergo a baseline health assessment via a questionnaire, baseline clinical chemistries, blood…
- Conditions
- General Health and Wellness, Energy and Vitality, Cognitive Function and Mental Health, Weight Management
- Trial name
- M4C Pilot (NCT06476236)
- Testing
- M4C
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Concordia University Wisconsin
Healthy Volunteers
Effects of Levocetirizine and Hydroxyzine on Cognitive and Psychomotor Functioning During Simulated Diving
Antihistamines are commonly used and currently levocetirizine is most frequently prescribed in the Netherlands. They are commonly used by divers, to solve ear, nose and throat problems, especially to open tubal passage.
- Trial name
- NCT01496911
- Testing
- Levocetirizine, Hydroxyzine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Aged, Exercise
Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness.
- Conditions
- Aged, Exercise, Cognition, Artificial Intelligence (AI)
- Trial name
- NCT07596082
- Testing
- Artificial intelligence-supported chatbot
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Caffeine, Sleep
Investigating the Acute and Chronic Effects of a Supplement Containing Caffeine, Vitamins, Minerals and Botanical Extracts on Cognition, Sleep and Wellbeing, in Healthy Volunteers
The aim of the study is to investigate the acute and chronic effects of a supplement containing Caffeine, Vitamins, Minerals and Botanical extracts on cognitive function, sleep and wellbeing, in healthy volunteers.
- Conditions
- Caffeine, Sleep, Cognitive Function, Wellbeing
- Trial name
- NCT06780774
- Testing
- Caffeine, Vitamins, Minerals and Botanical Blend
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Cancer-related Cognitive Impairment, Oncology
Effects of a Cognitive Training Program on Chemotherapy-induced Cognitive Impairment (Chemobrain) in Breast Cancer Patients Undergoing Active Treatment
Introduction: Given the increase in breast cancer survival rates, resulting from technological and biomedical advancements, it is essential to conduct an exhaustive study of the secondary symptoms associated with the oncological…
- Conditions
- Cancer-related Cognitive Impairment, Oncology, Breast Cancer, Cognitive Training
- Trial name
- NCT06686823
- Testing
- Health Education Program, Cognitive Training Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Physical Exercise, Cerebrovascular Function
Exercise and Brain Vascular Function
Cognitive performance is negatively related to an impaired glucose metabolism, possibly due to impairments in brain vascular function.
- Conditions
- Physical Exercise, Cerebrovascular Function, Cerebral Blood Flow, Glucose Metabolism
- Trial name
- NCT03272061
- Testing
- Aerobic-based exercise program
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cognitive Functions
Cognitive Functions in Women's National Sitting Volleyball Players
This study investigates the effects of a multidimensional, 13-component sleep hygiene optimization intervention on cognitive performance (executive functions, cognitive flexibility, and psychomotor speed) and objective sleep…
- Trial name
- NCT07857720
- Testing
- Multidimensional Sleep Hygiene Optimization Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University