Clinical trials: Cognitive/Functional Effects
Sleep Deprivation
The Stockholm Sleepy Brain Study: Effects of Sleep Deprivation on Cognitive and Emotional Processing in Young and Old
The main purpose of this study is to investigate the effects of partial sleep deprivation (PSD) on resting state brain connectivity, emotional contagion, empathy, and emotional regulation.
- Trial name
- NCT02000076
- Testing
- Partial sleep deprivation allowing 3 h sleep at night, Full sleep
- Where
- Sweden
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mats Lekander
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Athletic Performance, Exercise
Endurance Trial: Ketone and Carbohydrate Supplementation
This randomized, double-blind, crossover study investigates the effects of exogenous ketone supplementation on physical and cognitive performance in amateur endurance athletes during exhaustive exercise.
- Conditions
- Athletic Performance, Exercise, Ketosis, Cognition
- Trial name
- NCT07792876
- Testing
- Carbohydrate beverage, (R)-1,3-butanediol, Standardized evening meal
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Physical Fitness, Cognitive Function
Comparison of the Cognitive, Dual-task and Physical Effects of 6 Programs With Older Adults
While the association of physical and/or motor and/or cognitive components with training can generate synergistic effects and thus create an efficient cognitive enrichment program, very few studies have focused on finding an…
- Trial name
- NCT05991011
- Testing
- Immersive and Interactive Wall Exergames, Complex Cognitive and Motor Activities program, exergames program
- Where
- 3 sites in France
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Alexandra Perrot
Parkinson's Disease
Effect of Stimulus Rate on Cognitive and Motor Activity in Young Subjects, Elderly Subjects, and Patients With Parkinson's Disease
The purpose of this study is to investigate how changes in the brain associated with Parkinson's disease influence the control of motor and thinking speed.
- Trial name
- NCT00026598
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Executive Function (Cognition)
CogniFit Computerized Cognitive Training in Primary School Students in Hong Kong
This study aims to address these gaps by conducting a comprehensive evaluation of the effects of CogniFit training in children. The primary objective of this study is to evaluate the effectiveness of CogniFit training on…
- Trial name
- NCT06766149
- Testing
- CogniFit Computerized Cognitive Training, Cogmed Computerized Cognitive Training
- Where
- Hong Kong
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Vasomotor Symptoms
Goji Berry and Vasomotor Symptoms Pilot Study
The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot…
- Trial name
- GOJI-VMS (NCT07660315)
- Testing
- Goji Berry Juice Powder, Goji Berry Powder
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy Subjects
Evaluation of the Effects of a Food Supplementation on the Improvement of Cognitive Functions in Healthy Seniors
The hypothesis of this study is to evaluate the effect of supplementation for 8 weeks on the improvement of cognitive functions in healthy seniors with or without mild cognitive decline.
- Trial name
- BioMind (NCT05472285)
- Testing
- Verum
- Where
- 2 sites in France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Robertet SA
Aging, Sarcopenia
Effect of Immunocal® With Exercise Versus Casein With Exercise on Aging Processes in Elderly Persons
Aging is typically associated with a decrease in skeletal muscle mass and muscle function, which contributes decisively to disability in old age and to the loss of quality of life.Resistance exercise can increase muscle strength…
- Trial name
- NCT00935610
- Testing
- Immunocal, Casein
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Immunotec Inc.
Vitamin D Deficiency, Metabolic Syndrome
Vitamin D Supplementation and Metabolism in Vitamin D Deficient Elderly
The purpose of this study is to examine the effects of Vitamin D supplementation on the reasons (mechanisms) underlying the development of type 2 diabetes, metabolic syndrome (high blood pressure, cholesterol, diabetes, body…
- Trial name
- VitD (NCT01145703)
- Testing
- RDA Vitamin D3 only, Vitamin D2/3 Repletion only, Vitamin D2/3 Repletion + AEX
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Hydration Status, Sport Performance
Effects of Dehydration on Motor Skills, Attention, and Performance in Adolescent Football Players
This study aims to investigate how hydration status affects attention, motor competence, and football skills in adolescent male football players aged 13-14 years.
- Conditions
- Hydration Status, Sport Performance, Football, Adolescent Athletic Performance
- Trial name
- NCT07320313
- Testing
- Euhydration Protocol, Hypohydration Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- bekir tokay
Brain Fog, Cognitive Impairment
Cognitive Task-Based Walking Effects on Cognition, Mood, Sleep, and Quality of Life in Older Adults With Brain Fog
This randomized controlled trial aims to investigate the effects of cognitive task-based walking exercise on cognitive function, depressive symptoms, sleep quality, and quality of life in older adults experiencing brain fog.
- Conditions
- Brain Fog, Cognitive Impairment, Geriatric Population
- Trial name
- NCT07396779
- Testing
- Cognitive Task-Based Walking Exercise, Walking-Only Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medipol University
Subjective Cognitive Decline (SCD)
Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline
The overall objective of this study is to examine the effect of polyamine supplementation on cognitive performance and further characterization of individuals with subjective cognitive decline.
- Trial name
- SmartAge (NCT03094546)
- Testing
- Polyamine
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Cognitive Change, Metabolic Syndrome, Protection Against
Nutritional Intervention for Sustaining Health (NURISH) Trial
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Metabolic Syndrome, Protection Against, Diet, Healthy
- Trial name
- NCT06437860
- Testing
- MIND Diet, Control Diet
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes Mellitus, Type 2, Cognitive Impairment
Diabetes and Cognitive Functions in Middle Age
This study will examine the effects of type II diabetes on cognitive functions and mood in middle-aged patients. In addition, the association between cognitive functions and glycemic controls is studied in patients.
- Conditions
- Diabetes Mellitus, Type 2, Cognitive Impairment, Hyperglycemia, Hypoglycemia
- Trial name
- DBC (NCT05919927)
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang
Bariatric Surgery, Alcohol Consumption
Effect of Moderate Alcohol Consumption to Cognitive Functioning After Roux-en Y Gastric Bypass
Objectives: Alcohol metabolism is changed in gastric bypass patients, leading to faster resorption and higher alcohol peak concentrations in blood.
- Conditions
- Bariatric Surgery, Alcohol Consumption, Cognitive Function
- Trial name
- NCT02380950
- Testing
- 250 ml alcohol consumption
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- eSwiss Medical & Surgical Center
Sedentary Behavior, Light Intensity Physical Activity
The Effect of Different Ways of Sitting on Cognitive Performance and Muscle Activity
Academic educations concurs with a lot of sitting. Studies have shown that prolonged sitting not only has disruptive effects on physical health, but also influence mental health and cognition negatively.
- Trial name
- NCT04716582
- Testing
- Sitting interrupted by light physical activity, Sitting with cognitive task, uninterrupted sitting
- Where
- Netherlands
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Elderly (people Aged 65 or More)
Leg Press Power Training with Visual Feedback Games Improves Physical, Cognitive, and Heart Health in Seniors
This study investigates the effects of lower limb leg press power training combined with visual feedback games on the physical performance, cognitive function, and heart rate variability (HRV) of older adults aged 65 and above.
- Trial name
- LPPT-VFG (NCT06714175)
- Testing
- Lower Limb Strength Training Program with Visual Feedback
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Mood, Energy
Effect of Frequent Interruptions of Prolonged Sitting on Self-perceived Levels of Energy, Mood, Food Cravings and Cognitive Function
This study is designed to test the effects of six 5 minute microbursts of physical activity spread across the day as compared to either a sedentary control condition or a single 30 minute bout of moderate intensity physical…
- Conditions
- Mood, Energy, Food Cravings, Cognitive Function
- Trial name
- NCT02717377
- Testing
- physical activity
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver