Clinical trials: Cognitive/Functional Effects
Exercise Physiology, Cognitive Function
Jackfruit Effects on Adipokines and Cognition in Boxers
This study investigates the effects of jackfruit oil extract on adipokine levels (Irisin, Omentin-1), brain-derived neurotrophic factor (BDNF), cognitive performance, and body measurements in healthy young boxers aged 18-25.
- Conditions
- Exercise Physiology, Cognitive Function, Adipokine Response, Brain-Derived Neurotrophic Factor (BDNF)
- Trial name
- NCT07268976
- Testing
- Jackfruit Supplement
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bayburt University
Physiological Responses to High-Intensity Exercise
Effects of the Q-Collar During High-Intensity Cycling Exercise
This study examined the effects of wearing the Q-Collar during high-intensity cycling exercise. Eleven recreationally trained male participants completed two 5-kilometer cycling time trials: one while wearing the Q-Collar and one…
- Trial name
- NCT07808710
- Testing
- Q-Collar™
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Healthy
Acute Effects of Breakfast Compared With No Breakfast on Cognitive Function and Subjective State in 11-13 Year Old Children
This study is a school-based, randomised, controlled, parallel groups trial to examine the acute effect of breakfast (ready-to-eat-cereal and milk) vs.
- Trial name
- NCT03979027
- Testing
- Breakfast: ready-to-eat-cereal and milk
- Where
- United Kingdom
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Hearing Loss, Sensorineural, Bilateral Vestibulopathy
Effect of Hearing Loss and Vestibular Decline on Cognitive Function in Older Subjects
The world population has been growing and aging dramatically, with a rising prevalence of dementia. Worldwide, around 50 million people have dementia, with 10 million new cases added every year.
- Conditions
- Hearing Loss, Sensorineural, Bilateral Vestibulopathy, Alzheimer Disease, Mild Cognitive Impairment
- Trial name
- GECkO (NCT04385225)
- Testing
- Longitudinal follow-up
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Resistance Exercise Performance, Cognitive Function
Effects of New Zealand Blackcurrant Supplementation on Exercise and Cognitive Performance in Resistance-Trained Adults
New Zealand blackcurrant (NZBC) is a supplement made from a berry naturally rich in plant compounds called anthocyanins. Researchers have studied these compounds for years and found that they may help the body by improving blood…
- Conditions
- Resistance Exercise Performance, Cognitive Function, Anaerobic Performance, Dietary Supplementation Athletic Performance
- Trial name
- NZBC-FORCE (NCT07619976)
- Testing
- Low-dose Blackcurrant Supplement, High-dose Blackcurrant Supplement
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jacksonville State University
Mild Cognitive Impairment
Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI
Mild Cognitive Impairment (MCI) is defined as an impairment in a single cognitive function, usually memory, other than normal cognitive decline with age, that does not fulfil dementia criteria.
- Trial name
- NCT06935812
- Testing
- Bimanual Exercise, Finger Exercise, Virtual Reality
- Where
- Cyprus
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Glycemic Response, Appetitive Behavior
Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults
Assess the impact of 100% grape juice with a meal on postprandial glycemic response and subsequent appetite, food intake and cognitive function.
- Trial name
- NCT03409497
- Testing
- Concord Grape Juice, Low flavonoid low essence beverage, Low flavonoid beverage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cognitive Impairment, Cognitive Decline
A Prospective, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of LasoperinTM on Cognitive Function in Healthy Adults
The potential impact of various dietary ingredients to improve cognitive function, mood, well-being, and overall levels of affects are largely undetermined.
- Conditions
- Cognitive Impairment, Cognitive Decline, Cognition Disorders in Old Age, Well-Being, Psychological
- Trial name
- COG (NCT05994391)
- Testing
- LasoperinTM, Placeo
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Irisin, Lactate
Effects of Different Types of Exercise on Irisin and Cognitive Performance (Exercise-Irisin)
Purpose The purpose of this study was to determine the acute effects of different exercise intensities on Irisin levels, trail making test performance, and feeling scale.
- Conditions
- Irisin, Lactate, Cognitive Function, Exercise Training
- Trial name
- Ex-Irisin (NCT07146490)
- Testing
- Low Exercise, Long Interval Exercise, Short Intevral Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Cannabis User
Effect of Acute Exercise on Cognitive Functions and Blood Markers of Brain Plasticity in Regular Chronic Cannabis Users
The endocannabinoid system (ECS) is a complex endogenous signaling system made up of transmembrane cannabinoid receptors (CB1 and CB2 receptors), their endogenous lipid-derived ligands (the endocannabinoids - eCBs), and enzymes…
- Trial name
- CANNABEX (NCT06081218)
- Testing
- activity test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Metabolic Processes
The Effects of Differing Cognitive Task Demands on Whole-body Energy Metabolism and Cerebral Blood-flow: Modulation by Multivitamins/Minerals and Coenzyme Q10
When completing difficult tasks, the brain requires faster delivery of energy sources (oxygen and glucose) via the blood. There is evidence to suggest that some nutritional supplements may increase blood circulation in the brain…
- Trial name
- NCT02381964
- Testing
- Supradyn® (1RDA+CoQ10), Supradyn® (3RDA)
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Functional Status, Cognitive Impairment
Effects of a Daily Cognition Training in Older Adults Without Cognitive Impairment
To evaluate the effectiveness of a daily cognition training programme versus a traditional cognitive stimulation programme in cognitively unimpaired older adults on cognitive function, emotional state, frailty and functionality.
- Conditions
- Functional Status, Cognitive Impairment, Occupational Therapy
- Trial name
- NCT05688163
- Testing
- programme based on everyday cognition, traditional cognitive stimulation
- Where
- Spain
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Schizophrenia, Schizoaffective Disorder
Effect of Varenicline on Cognitive Function in Cigarette Smokers With Schizophrenia
Smokers with schizophrenia have more difficulties quitting smoking than smokers without a mental disorder. Varenicline (Champix) is a new stop smoking medication with a unique mechanism of action.
- Trial name
- NCT01093365
- Testing
- Varenicline
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Schizoaffective Disorder
Effects of Modafinil on Brain Function in Patients With Schizophrenia
This study will evaluate whether modafinil improves cognition in patients with schizophrenia and healthy volunteers. Modafinil is a drug that has been FDA approved for day-time sleepiness and allegedly increase the amount of the…
- Trial name
- NCT00057707
- Testing
- Modafinil, Functional MRI, Neuropsychological Testing
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Mood, Cognitive Performance
The Effects of A Proprietary Spearmint Extract on Cognitive Performance
This study was designed to evaluate the chronic effects of a proprietary spearmint extract over 90 days of supplementation on aspects of cognitive performance (cognitive function and active reaction time), subjective mood, and…
- Conditions
- Mood, Cognitive Performance, Sleep
- Trial name
- NCT02518165
- Testing
- Proprietary spearmint extract
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Sarcopenia
Protein Supplementation and Muscle Function in the Elderly
Sarcopenia is a geriatric syndrome associated with functional lost and disability, leading to an increase in healthcare costs. Physical activity, especially multicomponent exercise program, seems to be the most effective…
- Trial name
- NCT03815201
- Testing
- Group 2, Group 1
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Geriatric Individuals, Cognitive Function
Attentional Focus Training in Older Adults
The ability to walk safely and efficiently is crucial for older adults to maintain their independence and minimize the risk of falls.
- Conditions
- Geriatric Individuals, Cognitive Function, Physical Performance
- Trial name
- NCT06700928
- Testing
- External focus training, Internal focus training, No attentional focus training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Müşerref Ebru YALÇIN
Healthy
The Effects of Synaquell on Brain Function
The purpose of this study is to investigate the dietary supplement, Synaquell (TM), for effects on brain function.
- Trial name
- NCT05041192
- Testing
- Synaquell
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cerebrovascular Disease
Aerobic Dance Training in Small Vessel Disease
Introduction: Cerebral small vessel disease (SVD) is associated with age-related disabilities including dementia, depression, physical and functional impairment. Chinese are more prone to developing SVD than Caucasians.
- Trial name
- ADTSVD (NCT02730065)
- Testing
- Structured Aerobic Dance Training Group, Stretching plus education
- Where
- 2 sites in Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mild Cognitive Impairment
Consumption of Potatoes, Avocados and Chickpeas and Cognitive Function in Older Adults
Cognitive impairment is also a major risk factor for development of dementia later in life. Findings from the investigators studies suggest that the carotenoids, lutein and zeaxanthin may be important in cognitive function in the…
- Trial name
- NCT01620567
- Testing
- avocado, potato or chickpea
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tufts University