Clinical trials: Cognitive/Functional Effects
Sports Fatigue
Effects of Dual-site Anodal Transcranial Direct Current Stimulation on Attention, Decision-making and Working Memory During Sports Fatigue in Elite Soccer Athletes
Investigation of the effects of dual-site anodal transcranial direct current stimulation over the dorsolateral prefrontal cortex or primary motor cortex on attention, decision-making and working memory during sports fatigue in…
- Trial name
- NCT06594978
- Testing
- dual-site anodal tDCS over the M1, dual-site anodal tDCS over the DLPFC
- Where
- China
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Healthy
Acute Effect of a Standardized Botanical Blend Rich in Polyphenols on Cognitive Functions in Healthy Students
Available literature suggests that flavanols-rich foods, and more especially monomeric flavanols-rich foods such as grape, can have an acute effect on cognitive functions via different mechanisms such as cerebral blood flow…
- Trial name
- NCT03508206
- Testing
- SBRP
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Activ'inside
Cognitive Function, Anxiety
A Virtual Clinical Trial to Examine the Effect of Magnesium Choline Citrate on Cognitive Function and Anxiety in Healthy Adolescents and Adults
The goal of this clinical trial is to examine the effect of Magnesium Choline Citrate on cognitive function and anxiety in healthy adolescents and adults.
- Trial name
- NCT07685613
- Testing
- Magnesium Choline Citrate
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nutrisol, LLC
Cognition, Healthy Volunteers
Effects of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Cognition, Dual-Task Performance, and Interoceptive Accuracy
This study aims to determine the simultaneous effects of transcutaneous auricular vagus nerve stimulation (taVNS) at two frequencies (30 Hz and 100 Hz) compared to sham stimulation on cognitive functions, dual-task performance…
- Trial name
- NCT07897175
- Testing
- taVNS 30 Hz, taVNS 100 Hz
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Toros University
Physical Activity
Investigations of the Effects and Associated Neural Mechanisms of Different Exercise in People With Metabolic Syndrome
Metabolic syndrome (MetS) is a risk for many chronic diseases of middle-aged and older adults. Hence, prevention and treatment of MetS is a crucial global health issue.
- Trial name
- NCT05672940
- Testing
- Aerobic plus resistance training, Stretching plus breathing training
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Muscle Strength, Cognitive Function Assessment
Omega-3 Fatty Acids and Muscle Strength
The purpose of the study is to evaluate the effects of 12-week supplementation with algae-derived DHA combined with strength training on muscle strength, neuromuscular parameters, post-exercise inflammation and cognitive…
- Trial name
- NCT07763574
- Testing
- Effects of Strength Training Combined With Omega-3s derived from algae on Muscle Strength and Cognitive Functions in adults, Effects of Strength Training Combined With Omega-3s derived from fish on Muscle Strength and Cognitive Functions in adults, Effects of Omega-3s derived from algae on Muscle Strength and Cognitive Functions in adults
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Cognitive Function, Mood
The Effects of Caffeine and L-theanine Both Alone and in Combination on Cerebral Blood Flow, Cognition and Mood
Although the beneficial effects of caffeine on cognition and mood have been reported in a number of studies, relatively few studies have looked at the effects of caffeine in combination with other phytonutrients despite the fact…
- Trial name
- NCT00981955
- Testing
- Caffeine and L-theanine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy, Older Adults
Group-Based Exercise Intervention to Prevent Cognitive and Motor Decline
The goal of this clinical trial is to evaluate the efficacy of the Ideomotor Program in healthy older adults living in the community.
- Trial name
- NCT07494149
- Testing
- Ideomotor, Control
- Where
- 2 sites in Italy
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Bergamo
Cognitive Functioning, Propofol
The Effect of General Anesthesia with Remimazolam and Propofol on Rhythmic State and Cognitive Function
This study want to observe the effects of remimazolam and propofol for general anesthesia on postoperative rhythm and cognitive function.
- Conditions
- Cognitive Functioning, Propofol, Remimazolam, Circadian Rhythm
- Trial name
- NCT06775366
- Testing
- Remimazolam, propofol
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Benzodiazepine Adverse Reaction, Depression, Anxiety
Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers.
- Conditions
- Benzodiazepine Adverse Reaction, Depression, Anxiety, Benzodiazepine Dependence
- Trial name
- NCT06250842
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Cognitive Function
Effect of Sprint Interval Training and Intermittent Fasting on Cognitive Function
Several lifestyle modifications, such as manipulating diet and exercise, have been shown to enhance cognitive function. This study aims to determine if a combination of Sprint Interval Training (SIT) and Time Restricted Eating…
- Trial name
- NCT05152719
- Testing
- Cognitive Performance
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Obesity, Cognitive Dysfunction
Endurance-strength Training in Obese Women
The aim of this study was to compare the effects of three months' endurance training and three months' endurance-strength training on selected psychological aspects in women with abdominal obesity.
- Conditions
- Obesity, Cognitive Dysfunction, Physical Exercise
- Trial name
- PSYCHENDOFIT (NCT04793451)
- Testing
- Endurance training, Endurance-strength training
- Where
- Poland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Healthy
Creatine Supplementation on Cognition in Children
Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.
- Trial name
- NCT01803230
- Testing
- creatine supplementation
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy
Effects of Dual-task Exercises on Gait Parameters and Cognitive Function in Elderly Women: A Randomized Controlled Trial
The training of a secondary task while walking, whether it is reasoning activities, memory or motor tasks, may enhance automation, walking performance, and postural control and, thus, minimize the risk of falls influenced by the…
- Trial name
- NCT02185157
- Testing
- dual -task exercises, Aerobic training
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Multiple Sclerosis
Aerobic Training Effects on Motor and Cognitive Performances in MS: an Exploratory Study With Structural and Functional MRI
Aerobic training (AT) induces cardiovascular, metabolic and muscular changes and has been proposed as a promising rehabilitative approach in elderly adults and in neurological patients to improve both motor and cognitive…
- Trial name
- NCT04097418
- Testing
- Aerobic training compared to conventional motor training
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Human Volunteers
The Effects of a Novel NMDA NR2B-Subtype Selective Antagonist, EVT 101, on Brain Function
The purpose of this study is to investigate the neurophysiological changes following single doses of EVT 101 using fMRI during rest and during cognitive tasks in young healthy male subjects.
- Trial name
- NCT00526968
- Testing
- EVT 101
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Evotec Neurosciences GmbH
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Aging, Physical Activity
Effects of Regular Exercise on Cerebrovascular Reserve in Older Adults
While it is well established that physical inactivity is a modifiable risk factor for vascular disease and cognitive decline, the mechanism by which exercise exerts its protective effect on the cerebral circulation and cognition…
- Conditions
- Aging, Physical Activity, Cognitive Function
- Trial name
- BIM (NCT03158337)
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University of Calgary