Clinical trials: Cognitive Health
Overweight, Memory Disorder
Translation of Obesity and Cognitive Program by Lay Health Educators
Obesity is a major public health problem among older adults, with 31% of non-institutionalized older persons (60 years+) in the US obese and projections indicating that this will rise to 40% by 2010.
- Trial name
- Coaches (NCT01377506)
- Testing
- lifestyle counseling, Cognitive Training
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Insomnia
Overcoming Insomnia: Impact on Sleep, Health and Work of Online CBT-I
Insomnia is a major public health concern. While cognitive behavior therapy for insomnia (CBT-I) is acknowledged as the best available intervention, there are unanswered questions about its wider dissemination, socio-economic…
- Trial name
- NORSE-3 (NCT02558647)
- Testing
- CBT for insomnia (CBT-I), Psycho-Education about Sleep (PE)
- Where
- 2 sites in Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Cardiac Arrest, Cognitive Function
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)
The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time…
- Trial name
- BRAINnHEART (NCT03579498)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Alzheimer's Disease, Aging
aeRobic Exercise and Cognitive Health
The purpose of the aeRobic Exercise and Cognitive Health (REACH) study is to understand how an aerobic exercise intervention might help promote brain health and cognition, thereby delaying the onset of clinical symptoms of…
- Trial name
- REACH (NCT02384993)
- Testing
- Enhanced Physical Activity
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Physical Activity
The Effects of an In-school Physical Activity Intervention on Adolescents' Brain Structure and Function
Physical activity has shown beneficial effects for cognitive and brain health, suggesting it may provide a highly scalable intervention to improve academic achievement.
- Trial name
- NCT03593863
- Testing
- Physical Education (PE) programme
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Meditation, Cognitive Reappraisal
Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study
This study will evaluate how a comprehensive meditation-based program, Inner Engineering, supports teens ages 15-18 in becoming more joyful, focused, resilient, and better equipped to manage stress and thrive.
- Conditions
- Meditation, Cognitive Reappraisal, Emotional Regulation
- Trial name
- THRIVE (NCT07173608)
- Testing
- Inner Engineering Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Mental Health Issue, Cognitive Symptom
PrimeCog: Primary Care Cognitive Testing
The PrimeCog study aims to describe the symptomatology and pathophysiology of stress-induced exhaustion disorder (SED) and major depressive disorder (MDD) compared to healthy controls (HC).
- Conditions
- Mental Health Issue, Cognitive Symptom, Primary Health Care
- Trial name
- PrimeCog (NCT06346535)
- Testing
- Cognitive Testing
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Cognitive Function, Physical Function
Effects of Exercise Board Games on Cognitive Function in Older Adults
This study aims to evaluate the effects of an exercise-based board game intervention on cognitive function, physical function, and health promotion among community-dwelling older adults.
- Trial name
- NCT07586696
- Testing
- Exercise-Based Board Game Intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Cognitive Decline, Cognitive Dysfunction
Brain Vascular and Neurocognitive Health
The overall research objective of this proposal is to determine the acute and chronic impact of transcranial photobiomodulation on indices of cerebral vascular health and neurocognitive function.
- Conditions
- Cognitive Decline, Cognitive Dysfunction, Alzheimer Disease, Vascular Disease, Peripheral
- Trial name
- NCT06497413
- Testing
- Transcranial Photobiomodulation, Transcranial Photobiomodulation helmet (Neuradiant 1070 Plus) with no light administered
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Depressive Symptoms, Well-Being, Psychological
Metacognitive Training-Silver BeWell in Older Adults
The present study seeks to examine the feasibility, acceptance and efficacy of Metacognitive Training-Silver (MCT-Silver) BeWell among older adults (ages 60 years and older) delivered in a community setting (e.g.…
- Trial name
- NCT06312241
- Testing
- Metacognitive Training-Silver BeWell
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Aging, Physical Activity
NEUROmuscular Training for Enhanced AGE Longevity
In recent years the research group on Prevention and Health in Exercise and Sport (PHES) has carried out numerous studies that have provided current and convincing evidence of the benefits of physical activity and exercise for…
- Conditions
- Aging, Physical Activity, Training
- Trial name
- NEUROAGE (NCT06620666)
- Testing
- Water-based power resistance training + Dietary supplement I (WPowDSI), Elastic band-based power resistance training + Dietary supplement I (EBPowDSI), Elastic band-based eccentric resistance training + Dietary supplement II (EBEccDSII)
- Where
- Spain
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Physical Activity, Physical Fitness
DanceOn50+: Effects of a Dance Program on Physical and Psycho-emotional Health
Aging is associated with a decline in physical and cognitive function affecting autonomy and the ability to perform daily living activities.
- Conditions
- Physical Activity, Physical Fitness, Well Being
- Trial name
- Dance On 50+ (NCT07158866)
- Testing
- Ballroom Dance, Multicomponent Exercise
- Where
- Portugal
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Care Giving Burden, Dementia
E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app
The goal of this clinical trial is to test whether a web-based application called the Pain Control Enhancement App (PACE-app) can support family caregivers in managing pain for their care recipients with dementia.
- Conditions
- Care Giving Burden, Dementia, Chronic Pain, Pain Management
- Trial name
- PACE-app (NCT07032350)
- Testing
- Web-based pain management support tool, Usual Pain Management Care
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Iowa
COVID-19
Uninterrupted and Interrupted Sitting in Long COVID-19
People who sit uninterrupted for prolonged periods time have been shown to have poorer cardiovascular health compared to those that regularly interrupt it (e.g. standing up and moving).
- Trial name
- NCT05453175
- Testing
- Interrupting sitting with Physical activity
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Winchester
Acceptance and Commitment Therapy, Mental Health, Cognitive Impairment,Colorectal Cancer
Effect of Acceptance and Commitment Therapy Based Interventions on Mental Health and Cognitive Impairment for Patients With Advanced Colorectal Cancer
The present study aims to: Determine the effect of acceptance and commitment therapy-based interventions on mental health and cognitive impairment for patients with advanced colorectal cancer.
- Trial name
- NCT05741255
- Testing
- Acceptance and Commitment Therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Functional Aging, Subjective Cognitive Concerns
A Multidimensional Behavioral Intervention for Those at Risk for Alzheimer's Dementia
This intervention is designed to promote enhanced use of compensation strategies including calendar and task list use, and organization systems, as well as increased engagement with brain health activities including physical…
- Conditions
- Functional Aging, Subjective Cognitive Concerns, Compensation Strategies, Brain Health Activities
- Trial name
- NCT03549078
- Testing
- Intervention
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aged
Benefits of Online Mahjong by Older Adults
This study aims to examine the clinical efficacy of online Mahjong in improving physical health, cognitive performance, happiness, laboratory biomarkers, and structural brain imaging (magnetic resonance imaging, MRI) by a…
- Trial name
- NCT05808426
- Testing
- Bonus Winner Mahjong
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Mental Health (Depression), Mental Health and General Well-being
Thrive at Home: A Virtual Reality Social Intervention for Older Adults
The goal of this clinical trial is to evaluate whether a virtual reality (VR) based social platform can improve mental health and social connection for older adults who receive in-home care.
- Conditions
- Mental Health (Depression), Mental Health and General Well-being, Loneliness, Well Being
- Trial name
- Thrive at Home (NCT07835568)
- Testing
- Full Virtual Reality Social Intervention, Abbreviated Virtual Reality Social Intervention
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of California, Santa Barbara
Psychological Stress
A Randomised Controlled Trial of Self-help Mindfulness-based Cognitive Therapy for Health Workers
This study examines whether a mindfulness-based self-help book is effective at reducing healthcare workers' levels of stress and improving their wellbeing.
- Trial name
- MindSHINE2 (NCT03030040)
- Testing
- The self-help book: Williams, M. & Penman, D. (2011). Mindfulness: A practical guide to finding peace in a frantic world. London: Piatkus.
- Where
- 2 sites in United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Memory Loss (Excluding Dementia), Healthy Lifestyle
Brain Health Program for Older Adults With Subjective Cognitive Decline
The investigators will compare two brain health programs in older adults with subjective cognitive decline and lifestyle risk factors for dementia.
- Conditions
- Memory Loss (Excluding Dementia), Healthy Lifestyle, Risk Reduction Behavior
- Trial name
- NCT05934136
- Testing
- My Healthy Brain 1, My Healthy Brain 2
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital