Clinical trials: Cognitive Intervention
Depressive Symptoms, Clinical Depression
Improving Mood in Assisted Living Settings
Late-life depression levels are escalating, and include 24% of all tenants of Assisted Living (AL) settings. A promising, novel intervention is a computerized visual speed of processing training program known as Road Tour.
- Trial name
- NCT01763216
- Testing
- Road Tour, Boatload of Crosswords
- Where
- 32 sites in United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Marianne Smith
Aged
Benefits of Online Mahjong by Older Adults
This study aims to examine the clinical efficacy of online Mahjong in improving physical health, cognitive performance, happiness, laboratory biomarkers, and structural brain imaging (magnetic resonance imaging, MRI) by a…
- Trial name
- NCT05808426
- Testing
- Bonus Winner Mahjong
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Suicidal Ideation, Suicidal and Self-injurious Behavior
Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
School-based mental health literacy interventions have been shown to reduce and/or prevent suicidal ideation and attempts. Most programs to date include an adapted version of Cognitive Behavioural Therapy (CBT) - the gold…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide Attempt
- Trial name
- NCT04770168
- Testing
- Cognitive Behavioral Therapy Curriculum
- Where
- Canada
- Volunteers
- 3,204 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Health Adult Subjects, Maltreament
Mindfulness Intervention for Maltreatment-Related Cognitive Decline
The goal of this clinical trial is to examine whether an online mindfulness-based training program can help improve cognitive function including attention, emotional regulation, and mental health (such as depression and anxiety)…
- Trial name
- NCT07066800
- Testing
- Mindfulness-Based Online Training Program
- Where
- South Korea
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Chilgok Hospital
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Burnout, Caregiver
Evaluation of the CBSM Program Online and in Person to Reduce Caregiver Burnout
Professional burnout is a common syndrome among healthcare workers, impacting both their well-being and the quality of care provided .
- Trial name
- Caregiver-CBSM (NCT06626061)
- Testing
- Cognitive Behavioral Stress management in in person group Format, Cognitive Behavioral Stress management Hybrid Format
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Functional Fitness, Cognitive Abilities
High-Intensity Exercise in Older Adults
The goal of this interventional study was to test the high-intensity interval training called Aphasia Physical Exercise (APEX) in healthy older adults. The main questions it aimed to answer were: 1.
- Trial name
- NCT06199661
- Testing
- APEX
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Hypertension, Cognitive Decline
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP <120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in…
- Trial name
- IMPACTS-MIND (NCT04797403)
- Testing
- Stepped-care protocol adapted from the SPRINT intensive-treatment algorithm
- Where
- United States
- Volunteers
- 1,306 people, healthy volunteers welcome
- Sponsor
- Tulane University
Motivational Intervention, Nicotine Anonymous
Motivation and Skills for Detained Teen Smokers
The long-term objective of this research is to increase the investigators understanding of effective smoking interventions for understudied adolescents at high risk for continued smoking into adulthood.
- Conditions
- Motivational Intervention, Nicotine Anonymous, Cognitive Behavior Therapy, Relaxation Therapy
- Trial name
- NCT01387516
- Testing
- Motivational Intervention, Relaxation Therapy, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Menopause, Stress, Psychological
Fascial Yoga in Menopausal Women
Aim: The aim of this study is to evaluate the effects of a structured fascial yoga-based behavioral intervention on perceived stress, cognitive control, and cognitive flexibility in menopausal women.
- Conditions
- Menopause, Stress, Psychological, Cognitive Flexibility, Nonpharmacological Interventions
- Trial name
- FascialYogaM (NCT07401810)
- Testing
- Fascial Yoga Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Mild Cognitive Impairment
Early Intervention in Mild Cognitive Impairment (MCI) With Curcumin + Bioperine
This is an additional study to the primary Mild Cognitive Impairment (MCI) study (LSU#H04-049; NCT00243451)that is underway of PET detection of Mild Cognitive Impairment.
- Trial name
- NCT00595582
- Testing
- curcumin + bioperine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Anxiety Symptoms, Depressive Symptoms
ICBT for Anxiety and Depressive Symptoms in Brazilian Young Adults
This study aims to investigate the effects of a selfguided internet-based cognitive behavioral therapy (ICBT) program on depressive and anxiety symptoms in young Brazilian adults.
- Trial name
- NCT06633679
- Testing
- Se Cuida Intervention
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Mild Cognitive Impairment, Subjective Memory Impairment
The Cognitive Ageing Nutrition and Neurogenesis (CANN) Trial
There is a dearth of research which takes a multi-compound approach to dietary interventions, in humans, aimed at improving outcome measures of cognition.
- Trial name
- CANN (NCT02525198)
- Testing
- fatty acid/flavonoid blend
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 259 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Distress, Psychological, Negative Affect
Nature Exposure Through Virtual Reality (NET-VR) in Older Adults
Daily exposure to nature is associated with improved mood and reduced anxiety symptoms in the overall population. Even brief contact with natural environments can lower stress and restore productivity.However, access to natural…
- Conditions
- Distress, Psychological, Negative Affect, Cognitive Functioning, Older Adults
- Trial name
- NET-VR (NCT07443657)
- Testing
- Nature-Based Virtual Reality Intervention, Waiting list
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Sleep Disorder, Insomnia
Brain Gym Therapy on Quality of Sleep Among Elderly People
This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities.
- Conditions
- Sleep Disorder, Insomnia, Cognitive Function Abnormal, Old Age; Debility
- Trial name
- BG/E (NCT06553690)
- Testing
- Brain Gym Therapy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Traumatic Stress Symptoms, Psychological Distress
Effectiveness of Cognitive Behavioral Intervention for Trauma in Schools (CBITS): A Study With Pakistani Adolescents
This study will evaluate whether a school-based counseling program, Cognitive Behavioral Intervention for Trauma in Schools (CBITS), helps reduce trauma-related symptoms and improve psychological functioning in adolescents in…
- Conditions
- Post Traumatic Stress Symptoms, Psychological Distress, Trauma Exposure
- Trial name
- NCT07768540
- Testing
- cognitive behavioral intervention for trauma in schools
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of Modern Languages
Obesity
MIND Diet Intervention and Cognitive Performance
This single-center, randomized trial examined the effect of MIND diet intervention on cognition and brain structure changes of healthy obese women over three months.
- Trial name
- MIND (NCT04383704)
- Testing
- New Dietary pattern ( Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND))
- Where
- Iran
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Intellectual Disability, Exercise
Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
Adults with intellectual disabilities (ID) have significantly lower levels of fitness compared to the general population. The health benefits of enhanced muscular strength in the general population are well established.
- Conditions
- Intellectual Disability, Exercise, Obesity
- Trial name
- NCT04616638
- Testing
- Resistance Training for Empowerment (RT-POWER), A traditional RT intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Quality of Life, Cognitive Decline
Health and Energy Through Active Living Every Day After Cancer Intervention for Cancer Survivors
The purpose of the Health and Energy through Active Living Every Day (HEALED) intervention, is to examine the effect of a web-based intervention on changes in device-measured physical activity (light and moderate-to-vigorous…
- Conditions
- Quality of Life, Cognitive Decline, Fatigue, Sleep
- Trial name
- HEALED (NCT05356988)
- Testing
- Physical activity experiment, Balance and flexibility control
- Where
- United States
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- American Cancer Society, Inc.
Aging
Brain Stimulation and Cognitive Training in Healthy Older Adults
The aim of this study is to investigate whether a tDCS-accompanied intensive cognitive training of working memory leads to performance improvement in healthy older individuals.
- Trial name
- TrainStim (NCT03838211)
- Testing
- Anodal tDCS, Intensive cognitive training
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald