Clinical trials: Cognitive Investigation
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI)
Evaluation of SCALE PET Software for Quantitative Brain PET Analysis in Alzheimer's Disease
The goal of this study is to learn if medical image analysis software, Neurophet SCALE PET, can enhance readers' amyloid beta positivity performance in people with Alzheimer's Disease.
- Trial name
- NCT07417540
- Testing
- Neurophet SCALE PET
- Where
- South Korea
- Volunteers
- 190 people
- Sponsor
- NEUROPHET
Mild Cognitive Impairment
Computerized Cognitive Training in Neurodegenerative Diseases (NDD2019)
The prevalence of neurodegenerative diseases is expected to increase over the next years, in parallel to the aging of the world population.
- Trial name
- NDD2019 (NCT04111640)
- Testing
- CoRe software, Control Group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Breast Cancer, Brain Metastasis
Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer
The incidence of brain metastases (BM) in metastatic breast cancer is increasing, due to the improvement in the control of systemic disease, and due to an improved detection through imagery.
- Trial name
- NCT01942980
- Testing
- Radiation therapy Brain metastasis in breast cancer
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Institut Paoli-Calmettes
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-1: A Clinical Trial for the Assessment of Lenalidomide in Amnestic MCI Patients
Accumulating evidence indicates that inflammation is prominent both in the blood and central nervous system (CNS) of Alzheimer's disease (AD) patients.
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegeneration
- Trial name
- MCLENA-1 (NCT04032626)
- Testing
- Lenalidomide 10 mg
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Bipolar Disorder, Bipolar Depression
Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up
This study aims to study prospectively for 8 months a sample of bipolar patients with acute depressive episode in order to identify that factors associated with functional impairment, with especial attention to the presence of…
- Trial name
- NCT01255982
- Where
- 24 sites in Spain
- Volunteers
- 249 people
- Sponsor
- AstraZeneca
Breast Cancer
Intellectual Impairment in Women With Breast Cancer
RATIONALE: Breast cancer and its treatment may cause changes in a patient's ability to think, learn, and remember. Gathering information about a woman's genes, brain function, and personal history may help doctors learn more…
- Trial name
- NCT00896324
- Testing
- Cognitive Rehabilitation, Active Neurofeedback Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Presymptomatic Huntington Disease
Assessment of the Psychological, Cognitive and Social Resources of Applicants for Huntington's Disease and Presymptomatic Genetic Testing
The purpose of this study is to assess the psychological, cognitive and social resources of applicants for Huntington's Disease and Presymptomatic Testing.
- Trial name
- PREHUNT (NCT02134561)
- Testing
- psychological interview, MRI, cognitive tests
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Angers
Alzheimer's Disease
Evaluation of E2609 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (Study: E2609-A001-101 Amendment 02)
Subjects will be adults aged 50 to 85 years who have subjective memory complaints and mild cognitive impairment or mild dementia due to Alzheimer's disease (AD).
- Trial name
- NCT01600859
- Testing
- E2609
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Eisai Inc.
Schizophrenia
Neurophysiological Evaluation of Schizophrenia Patients After Cognitive and Physical Intervention
Neurophysilogical, neuropsychological evaluation and cognitive and physical training
- Trial name
- NCT03899662
- Testing
- Cognitive Training, Physical Training
- Where
- Greece
- Volunteers
- 4 people
- Sponsor
- Aristotle University Of Thessaloniki
Concussion, Brain, Sports-related Concussion
Ecological Test Standardization for Concussion Assessment in Football Players
Concussion is a major concern in the sports world. It represents an immediate and transient alteration of neurological functions due to a direct or indirect trauma, with or without loss of consciousness.
- Conditions
- Concussion, Brain, Sports-related Concussion, Football Players, Traumatic Brain Injury, Mild
- Trial name
- COMOFOOT (NCT07431320)
- Testing
- Ecological Dual-Task Cognitive Assessment, Visuospatial Working Memory Ecological Test
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Mutualiste de Rééducation et de Réadaptation Fonctionnelles de Kerpape
Cardiovascular Diseases
Novel Strategies for Reducing Heart Disease Risk Disparities
This Western Pennsylvania-based study will (1) improve cardiovascular risk stratification to identify high-risk populations, (2) identify differences in cardiovascular risk, (3) evaluate mechanisms for population differences in…
- Trial name
- HeartSCORE (NCT00143923)
- Testing
- Nutrition, Exercise, Stress Management Counseling, usual care
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Dyssynergic Defaecation
Efficacy of Cognitive Behavioral Therapy Administered in Patients With Dyssynergic Defecation
The aim of this study is to evaluate the effectiveness of cognitive-behavioral therapy when used in conjunction with lifestyle modifications and pelvic floor rehabilitation.
- Trial name
- NCT07488442
- Testing
- Pelvic floor rehabilitation, Pelvic floor rehabilitation+cognitive behavioral therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara Etlik City Hospital
Cognitive Impairment, Coginitive Assessment
A Modified Test of Goal-directed Behaviour: a Feasibility Study
Cognitive assessment plays an important part in decision making in acute neurological settings, partly because difficulties with cognitive skills such as attention, memory and executive functioning (which includes planning and…
- Trial name
- NCT07484048
- Testing
- Five cognitive tasks
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Neurocognitive Disorders
Cognitive Functions on Coronary Surgery
The aim of this study is to examine the effects of different but safe levels of arterial oxygen levels used in cardiac surgeries on cerebral oxygenation during the operation.
- Trial name
- NCT04725708
- Testing
- procedure: cerebral oxygenation intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Down Syndrome
Rivastigmine Study in Adolescents With Down Syndrome
The purpose of this study is to determine if short term use of rivastigmine can improve functional abilities (for example, language, memory, and executive function) in adolescents with Down syndrome.
- Trial name
- DS-Riv (NCT01084135)
- Testing
- Rivastigmine
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Duke University
Postoperative Delirium
Risk Assessment for Postoperative Delirium
Postoperative delirium (POD) - a temporary state of confusion - is a frequent complication of surgery, which most commonly occurs in elderly patients.
- Trial name
- RAPID (NCT02377115)
- Testing
- Tablet computer application
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Basel, Switzerland
HIV-1
Evaluation of a Short Version Computerized Test for Processing Speed to Detect Cognitive Disorders in HIV+ Patients
The objective of this prospective study is to evaluate the prevalence of neurocognitive impairments in HIV infected patients comparing patients with and without HAART.
- Trial name
- NEURACog (NCT03279835)
- Testing
- Classic evaluation of neurocognitive functions, New evaluation of neurocognitive functions
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Alcohol Use Disorder, Cognition Disorders
Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder
Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations.
- Trial name
- TIPA (NCT07468825)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Neuromodulation Combined With Dual FES Cycling and Cognitive Training After Stroke
This study will evaluate the effects of functional electrical stimulation (FES) cycling, cognitive task training, and non-invasive photobiomodulation on cognitive and upper-limb motor performance in adults after stroke.
- Trial name
- NCT07807176
- Testing
- Functional Electrical Stimulation Cycling, Cognitive Task Training, Transcutaneous Auricular Photobiomodulation
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
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