Clinical trials: Colonic Neoplasms
Colorectal Cancer
Increasing CRC Screening in Community Health Centers Through Mobile Messaging Optimization
The goal of this interventional study is to create and test a comprehensive and low burden text message program within existing Community Health Centers (CHC) electronic records system to encourage patients to complete at home…
- Trial name
- CoSMMO (NCT07569250)
- Testing
- Personalized Text Message, Screening Concerns Text Message, Message Framing Text Message
- Where
- 4 sites in United States
- Volunteers
- 7,220 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Colorectal Cancer
Identification of New Colorectal Cancer Genes
The purpose of this study is to define new genes for family risks of developing colon cancer.
- Trial name
- NCT00582335
- Where
- United States
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colorectal Carcinoma
A Web-Based Dyadic Intervention for Colorectal Cancer
This clinical trial studies how well a web-based dyadic intervention works to manage psychoneurological symptoms for patients with colorectal cancer and their caregivers.
- Trial name
- CRCweb (NCT05663203)
- Testing
- Internet-Based Intervention, Interview, Survey Administration
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Emory University
GENE EXPRESSION, Colorectal Cancer
Scottish Vitamin D Intervention Study
AIMS To identify the underlying mechanism by which Vitamin D reduces colorectal cancer risk. OBJECTIVES To demonstrate the effects of vitamin D supplementation on serum vitamin D levels.
- Trial name
- (SCoViDS) (NCT04868227)
- Testing
- FULTIUM D3 VITAMIN D3
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Colorectal Cancer
Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
Multicenter, multinational, randomized, 3-arm, double-blind, phase II clinical study with 2400mg mesalamine, 1200mg mesalamine or placebo for prevention of colorectal neoplasia in Lynch Syndrome patients for 2 years.
- Trial name
- MesaCAPP (NCT03070574)
- Testing
- mesalamine 2400 MG (5-ASA), mesalamine 1200 MG
- Where
- 6 sites in Austria, Germany and 4 more
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Christoph Gasche
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Colorectal Cancer
Does Knowing One's Estimated Colorectal Cancer Risk Influence Screening Behavior?
This study is designed to examine the impact of telephone-based colorectal cancer risk assessment on colorectal screening attitudes and behavior among previously unscreened adults ages 50 to 75.
- Trial name
- NCT03819920
- Testing
- Risk Assessment (CCRAT), Usual Care (UC)
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Stanford University
Breast Cancer, Colorectal Cancer
Michigan Genetic Hereditary Testing (MiGHT)
The primary purpose of this study is to compare three interventions, two experimental and one standard of care (usual care), to see if the experimental interventions will increase the likelihood of a participant obtaining…
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- MiGHT (NCT05162846)
- Testing
- Publicly available genetic testing resources, Virtual genetics navigator, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Colorectal Cancer, Endometrial Cancer
Discovering New Targets for Colorectal and Endometrial Cancer Risk Reduction
The primary aim of this study is to collect and store data, tissue, and personal and family histories from patients being screened for colorectal cancer and/or endometrial cancer at NYPH and WCM for routine clinical care and to…
- Conditions
- Colorectal Cancer, Endometrial Cancer, Hereditary Cancer Syndromes
- Trial name
- NCT06096688
- Where
- United States
- Volunteers
- 1,120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Colorectal Cancer, Breast Cancer
A Sustainable Approach to Increasing Cancer Screening
Parent study: A Coordinated Approach to Cancer and Health (CATCH), was designed to compare the efficacy of two intervention arms (described below) intended to increase breast, cervical, and colon cancer screening rates among…
- Conditions
- Colorectal Cancer, Breast Cancer, Cervical Cancer
- Trial name
- CATCH (NCT01395459)
- Testing
- IVR only, IVR+PCC
- Where
- United States
- Volunteers
- 13,675 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Adenomatous Polyps
Does Cap Assisted Colonoscopy Improve Detection of Adenomatous Polyps? (CAP Trial)
Effectiveness of screening colonoscopy in cancer prevention relies on the detection and removal of adenomatous polyps. However, a substantial rate of adenomas is missed during a colonoscopy.
- Trial name
- CAP (NCT01935180)
- Testing
- Colonoscopy Cap
- Where
- 2 sites in United States
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
Colorectal Cancer
Virtual Reality During Colonoscopy Procedures
Colorectal cancer (CRC) in the United States (US) is the fourth leading cause of cancer- related deaths. In Puerto Rico (PR), the incidence and mortality rate of CRC is higher (41% and 14%) in comparison to the mainland US (38%…
- Trial name
- VR (NCT06236386)
- Testing
- VR Experience
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Colorectal Cancer
Efficacy of Perioperative Duloxetine as a Part of Multimodal Analgesia in Laparoscopic Colorectal Cancer Surgery
Our aim will be to evaluate the efficacy of perioperative Duloxetine in decreasing acute postoperative pain after laparoscopic colorectal cancer surgery and its role in reducing postoperative morphine requirements
- Trial name
- NCT04294953
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Inflammatory Bowel Disease, Crohn Disease
Pneumococcal Vaccination in Patients With Inflammatory Bowel Disease
Patients with inflammatory bowel disease (IBD) will be assessed for immunologic response to pneumococcal vaccination. Patients with IBD meet criteria as outlined by the Centers for Disease Control (CDC) for pneumococcal…
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Ulcerative Colitis
- Trial name
- NCT00829595
- Testing
- 23-valent polysaccharide pneumococcal vaccine (Pneumovax TM)
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Colorectal Carcinoma
Educational Intervention - Improving Knowledge and Screening Rates for Colorectal Cancer
This clinical trial studies how well educational intervention works in improving knowledge and screening rates of colorectal cancer.
- Trial name
- NCT03287453
- Testing
- Educational Intervention, Survey Administration
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Colonic Polyp, Colorectal Cancer
Computer Aided Diagnosis of Colorectal Polyps
The purpose of this study is to assess whether computer aided technology (CAD) can help in the diagnosis of polyps found the bowel compared with visual inspection alone and therefore whether it is beneficial in helping clinicians…
- Trial name
- EndoBrain (NCT04510545)
- Testing
- Endobrain, Computer Aided Diagnosis (CAD)
- Where
- United Kingdom
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Cancer Colon
Blood-Based Colorectal Cancer (CRC) Screening Implementation Into Clinical Practice Highlands
This is a prospective implementation study that will include patients that are identified as being average risk for colorectal cancer (CRC) according to USPSTF guidelines and who have opted to be screened for CRC.
- Trial name
- NCT06119425
- Testing
- blood-based CRC screening
- Where
- United States
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Ballad Health
Colorectal Cancer
Evaluation of an Intervention to Increase Colorectal Cancer Screening in Primary Care Clinics
This study is a three-arm randomized controlled trial to implement and evaluate the relative effects of: 1) clinic-focused intervention; 2) combined patient- and clinic-focused intervention, and 3) usual care on the provision of…
- Trial name
- NCT00737646
- Testing
- Usual care, Clinic-focused intervention, Clinic- and patient-focused
- Where
- 3 sites in United States
- Volunteers
- 5,066 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Colonic Neoplasms
Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer
The purpose of this study is: to determine neutrophil activity in patients with colon cancer, to determine levels sFas, sFasL and IL - 17 in serum of healthy volunteers and colon cancer patients and establish its prognostic…
- Trial name
- NCT00860691
- Testing
- Therapeutic conventional colorectal surgery, Therapeutic laparoscopic colorectal surgery, Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Colorectal Cancer
Effects of Weight on Inflammation and Colon Cancer Risk
An observational study designed to compare colonic cytokine concentrations in lean versus obese individuals
- Trial name
- NCT02884024
- Testing
- no intervention
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Tufts University