Clinical trials: Colonoscopy Procedures
Pain During Colonoscopy
Improving Quality of Colonoscopy Using a 3D-imager
Coloscopy may be a painful procedure for the patient. This is due to a loop-formation of the coloscope. A 3D-real time imager produced by Olympus creates a real-time image of the scope while a traditional fluoroscopy device will…
- Trial name
- NCT00519129
- Testing
- 3D-imager
- Where
- Norway
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Colonoscopy, Endoscopy
Evaluation of PillCam® Colon 2 Capsule Endoscopy Regimen
The purpose of the study is to test the effect of a bowel preparation and boosts regimen on PillCam® procedure, colon cleanliness and capsule excretion time.
- Trial name
- NCT01185002
- Testing
- PillCam® COLON 2 procedure using MgC boosts, PillCam® COLON 2 procedure using Suprep boosts, PillCam® COLON 2 procedure using reduced dose of Suprep boosts
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colorectal Cancer, Adenoma
G-Eye Advanced Colonoscopy For Increased Polyp Detection Rate-randomized Tandem Study With Different Endoscopist
The purpose of this study is to compare the adenoma detection rate of G-EYE™ high definition colonoscopy with that of standard high definition colonoscopy.
- Trial name
- NCT02066064
- Testing
- Standard Colonoscopy, G-EYE(TM) Colonoscopy
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Smart Medical Systems Ltd.
Colorectal Neoplasm
Efficacy of Cap-assisted Chromoendoscopy as a Screening Test for Colorectal Neoplasm Using Web-based Research Network
The investigators plan to conduct a multi-center, randomized controlled trial to investigate the efficacy of cap-assisted chromoendoscopy as a screening test for detection of colorectal polyp.
- Trial name
- CapACE (NCT01112280)
- Testing
- cap-assisted chromoendoscopy
- Where
- 14 sites in South Korea
- Volunteers
- 1,905 people, healthy volunteers welcome
- Sponsor
- Korean Association for the Study of Intestinal Diseases
Adenoma Colon
White Light vs Narrow Band Imagingin the Diagnosis of Right Sided Colonic Polyps in Asymptomatic Subjects Undergoing Screening Colonoscopy
A randomized controlled crossover study to determine if narrow band imaging or white light endoscopy is superior in detecting right colonic polyps in average risk subjects undergoing screening colonoscopy
- Trial name
- WLEvsB-NBI (NCT05935124)
- Testing
- WLE first, then B-NBI
- Where
- Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Western Sydney Local Health District
Polyps
Cap-fitted Colonoscopy: a Randomized, Tandem Colonoscopy Study of Adenoma Miss Rates
This is a test in which a thin, black, flexible tube with a lighting system on the end is passed through the anus, into the rectum, in order to examine the large bowel or intestine, also called the colon.
- Trial name
- NCT00577083
- Testing
- Cap-fitted colonoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Nitrous Oxide
Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA
Colon cancer is the second most common cancer in men and the third most common cancer in women worldwide. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort and to…
- Trial name
- NCT04305158
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
GLP - 1, Bowel Preparation for Colonoscopy
The Impact of GLP Medication on Colonoscopy Bowel Preparation Quality
The goal of this clinical trial is to learn how GLP-1 and GIP agonists effect bowel preparation in patients scheduled for colonoscopies.
- Trial name
- NCT07127354
- Testing
- Continue GLP/GIP
- Where
- 3 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colonoscopy
Comparing Oral Preparation With Macrogol (Moviprep) and Natriumdihydrogenphosphatdihydrat (Phosphoral)
The purpose of this study is to determine whether Moviprep or Phosphoral is the best method of bowel preparation before colonoscopy - seen by the patients and by the endoscopist.
- Trial name
- NCT01705262
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pediatric ALL
The Impact of a Smartphone App on the Quality of Pediatric Colonoscopy Preparations
The investigators developed a smartphone app that guides pediatric patients and their families through colonoscopy prep in an attempt to see if an app could improve the colonoscopy process.
- Trial name
- NCT04590105
- Testing
- Smartphone App "SB Colonoscopy Prep", Written Instruction
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Colorectal Cancer
Informed Choice - Compass
The primary objective of this study is to evaluate the impact of a theoretically grounded video that includes information about CRC screening modality choices on CRC screening rates and time adherent to CRC guidelines.
- Trial name
- NCT05246839
- Testing
- Brief Video, Brief Video Plus
- Where
- 39 sites in United States
- Volunteers
- 1,823 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Colorectal Polyps
AI in Predicting Polyp Pathology and Endoscopic Classification
Background: Colonoscopy with optical diagnosis based on the appearance of polyps can guide the selection of endoscopic treatment methods, reduce unnecessary polypectomy procedures and the need for tissue pathological diagnosis…
- Trial name
- NCT06773832
- Testing
- Real-time Artificial Intelligence Model for Diagnosing Colorectal Polyp Pathology and Endoscopic Classification
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Colorectal Polyps
A Trial of an Audit and Feedback Report to Improve Colonoscopy Performance
This project aims to measure the impact of a physician report card (also called an audit \& feedback report) on colonoscopy performance.
- Trial name
- NCT02595775
- Testing
- Individualized A/F report, A/F report plus a high intensity intervention, A/F report plus a low intensity intervention
- Volunteers
- 833 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Colon Cancer, Colon Polyp
Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)
The study will compare the use of cold snare, hot snare, cold EMR, and hot EMR for polyp resection. Although previous studies have compared two of the potential resection methods, no previous study has evaluated all four of the…
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma
- Trial name
- NCT03462706
- Testing
- Cold Snare, Hot Snare, Cold EMR
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colonoscopy, Gastrointestinal Microbiome
Effect of Carbon Dioxide Insufflation and Appendix on the Restoration of Intestinal Microecology After Colonoscopy.
The goal of this observational study is to learn about Influencing factors of intestinal microecological changes before and after colonoscopy.
- Conditions
- Colonoscopy, Gastrointestinal Microbiome, Appendix, Carbon Dioxide Insufflation
- Trial name
- NCT05637021
- Testing
- Carbon dioxide insufflated during colonoscopy
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
Colonoscopy
Randomized Trial Comparing Carbonated Drink With Water as a Solvent for Colonoscopy Solution
This prospective randomized trial will be conducted in all patients undergoing elective colonoscopies from February 2020 to August 2020 in Dowites Operation Theater Endoscopy suite by surgical unit III, Civil Hospital Karachi.
- Trial name
- NCT04316858
- Testing
- Sodium phosphate, Water, Zero calorie carbonated drink
- Where
- Pakistan
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Colonic Polyps
Detection of Colorectal Adenoma by Optical Enhancement Technology vs. High-Definition Colonoscopy
Optical Enhancement Technology might be superior to the conventional HD-WL in detecting colorectal adenomas
- Trial name
- NCT02865382
- Testing
- white light was used for colonoscopy withdrawal, OE mode was used for colonoscopy withdrawal
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Yanqing Li
Bowel Disease
Plenvu 1 - Questionnaire Study Exploring Patients Preference in Bowel Preparation Timings for Morning Colonoscopy
Questionnaire study exploring patients preference in bowel preparation timings for morning colonoscopy.
- Trial name
- NCT04456790
- Where
- United Kingdom
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Colonoscopy, Patient Compliance
Evaluation of Information on Bowel Preparation for Morning Colonoscopy
Background: In randomized controlled trials, split-dose bowel preparation for colonoscopy has been shown to provide better bowel cleansing than day before bowel preparation.
- Trial name
- NCT03650725
- Testing
- Mandatory Split bowel preparation
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Harminder Singh