Clinical trials: Community-Acquired Infections
Abscess
Trial of Antibiotic Treatment for Skin Abscess in Patients at Risk for Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection
Patients will be enrolled in a multi-center study to prospectively evaluate outcome after treatment for an uncomplicated skin abscess. All patients will receive incision and drainage and wound cultures.
- Trial name
- NCT00829686
- Testing
- Septra
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Pneumonia, Community-Acquired, COVID-19 Pneumonia
Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19.
Pneumonia, which can be acquired in the community (including influenza and COVID-19), is a leading cause of mortality. The risk of severe cardiovascular diseases events (stroke, myocardial infarction, pulmonary embolism)…
- Conditions
- Pneumonia, Community-Acquired, COVID-19 Pneumonia, Cardiovascular Diseases
- Trial name
- HOMI-LUNG CAP (NCT06601998)
- Testing
- Blood samples and Oropharyngeal swab, Six-minute walk test, Spirometry, ECG, Heart ultrasound and cardiopulmonary exercise stress testing, Completion of questionnaires of symptoms
- Where
- 19 sites in Greece
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Hellenic Institute for the Study of Sepsis
HIV/AIDS, Mobile Health
Evaluation of a Multi-Component Intervention to Support HIV Testing and Linkage to Services Among MSM in Peru
This study is testing a new program designed to improve access to HIV testing and help connect people with available treatment or prevention services, based on their test result.
- Conditions
- HIV/AIDS, Mobile Health, Feasibility Studies, Qualitative Research
- Trial name
- MERCURY (NCT07074899)
- Testing
- Multi-component HIV testing and linkage-to-services intervention
- Where
- 2 sites in Peru
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Use of Research Evidence
Effects of an Evidence Service on Community-based AIDS Service Organizations' Use of Research Evidence
The investigators have developed an online database called 'Synthesized HIV/AIDS Research Evidence' (SHARE), which is designed to support the use of research evidence by those working in the HIV/AIDS sector.
- Trial name
- NCT01257724
- Testing
- SHARE (Synthesized HIV/AIDS Research Evidence)
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ontario HIV Treatment Network
Pneumonia, Chronic Obstructive Pulmonary Disease
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia
Pneumonia is a major infectious cause of death worldwide and imposes a considerable burden on healthcare resources. Obstructive lung diseases (COPD and Asthma) are increasingly important causes of morbidity and mortality…
- Conditions
- Pneumonia, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT03473119
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
Abscesses
Prospective Randomized Trial of Bactrim on 7 Day Outcome in Patients With Uncomplicated Abscesses
Patients will be enrolled in a multi-center study to prospectively evaluate outcome after treatment for an uncomplicated skin abscess. All patients will receive incision and drainage and wound cultures.
- Trial name
- NCT00973765
- Testing
- bactrim
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Infections, Streptococcal
COMPAS (Clinical Otitis Media & Pneumonia Study): Pneumonia & Acute Otitis Media (AOM ) Efficacy Study of the Pneumococcal Conjugate Vaccine
This is a study in a large number of healthy children less than 3 years old to measure the efficacy of GlaxoSmithKline (GSK) Biologicals' 10-valent pneumococcal conjugate candidate vaccine (Synflorix vaccine, or GSK1024850A) to…
- Trial name
- NCT00466947
- Testing
- Pneumococcal conjugate vaccine GSK1024850A, Havrix, Engerix-B
- Where
- 22 sites in Argentina, Colombia and 1 more
- Volunteers
- 23,802 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV/AIDS
Direct and Spillover Impacts of a Community-Level HIV/AIDS Program
The HIV/AIDS crisis in Sub-Saharan Africa has left millions of children orphaned. These children, who are potentially infected with HIV themselves, are highly vulnerable and face some serious risks to their health and overall…
- Trial name
- FCC (NCT03880175)
- Testing
- FCC (Força à Comunidade e Crianças) program- direct beneficiary, FCC (Força à Comunidade e Crianças) program- non-direct beneficiary, Anti Stigma Information
- Where
- Mozambique
- Volunteers
- 3,658 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pneumonia
A Polymerase Chain Reaction (PCR) - Based Method to Improve Antibiotic Prescribing for Pneumonia
Pneumonia, or lung infection, is usually treated with antibiotics targeted against the organisms that the physician guesses are causing the problem. The determination of the exact cause of a patient's pneumonia is difficult.
- Trial name
- NCT00867841
- Testing
- nasopharyngeal swab
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
HIV, AIDS
Community-based Accompaniment With Supervised Antiretrovirals in Lima, Peru
Using quantitative and qualitative data, this study will assess the impact of community accompaniment with supervised antiretrovirals (CASA) on HIV-positive individuals and community members in Lima, Peru.
- Conditions
- HIV, AIDS, HIV Infections
- Trial name
- CASA (NCT01070017)
- Testing
- DOT-HAART
- Where
- Peru
- Volunteers
- 1,244 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Childhood Pneumonia, Mycoplasma Pneumonia
Evaluation of Pathogenesis and Diagnosis of Mycoplasma Pneumoniae Community-acquired Pneumonia (CAP)
To investigate the Mycoplasma pneumoniae-specific circulating antibody-secreting cell (ASC) response and Mycoplasma pneumoniae-specific interferon (INF)-γ-secreting T cell response, along with polymerase chain reaction (PCR) and…
- Conditions
- Childhood Pneumonia, Mycoplasma Pneumonia, Antibody-secreting Cells, Enzyme-linked Immunospot (ELISpot)
- Trial name
- myCAP (NCT03613636)
- Testing
- Enzyme-linked immunospot (ELISpot) assay [Blood]
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
HIV Infections
C2P - Phase III: MPowerment and Community Promise
One of the objectives of the C2P coalition is the successful delivery of a CDC-endorsed community-level HIV prevention program aimed at changing the risk profiles of youth.
- Trial name
- NCT00381784
- Testing
- Printed materials, Peer advocates
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV-infection/Aids
Community-Based Peer Facilitator Intervention (Zimbabwe)
The goal of this community randomized operations research study was to evaluate the effect of a peer-facilitated community support group intervention on uptake of maternal and neonatal child health (MNCH) and PMTCT services and…
- Trial name
- NCT02496793
- Testing
- Peer-facilitated community support group
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
HIV, Substance Use Disorders
The Collaborative Care PrTNER Study
A randomized controlled trial to assess the ability of a Collaborative Care Prevention, Treatment, Navigation, Engagement, Resource (PrTNER) intervention to increase initiation of preexposure prophylaxis (PrEP) (for those at-risk…
- Conditions
- HIV, Substance Use Disorders, Substance Use, AIDS
- Trial name
- PrTNER (NCT06585631)
- Testing
- CC PrTNER
- Where
- 2 sites in United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Abscess, Methicillin-Resistant Staphylococcus Aureus Infection
Trial of Septra for Uncomplicated Skin Abscesses in Patients at Risk for Community Acquired Methicillin-Resistant Staphylococcus Aureus Infection
Patients will be enrolled in a multi-center study (Wilford Hall Medical Center and Brooke Army Medical Center) to prospectively evaluate outcome after treatment for an uncomplicated skin abscess.
- Trial name
- NCT00822692
- Testing
- Trim/ Sulfa DS
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
HIV/AIDS, Pre-exposure Prophylaxis
Linking High-Risk Jail Detainees to HIV Pre-Exposure Prophylaxis: PrEP-LINK
Our proposed study will: provide a novel exploration of facilitators and barriers to PrEP; allow us to target hard to reach populations, including men who have sex with men (MSM) and substance users (both of which are top funding…
- Trial name
- NCT04064567
- Testing
- PrEP-LINK, Enhanced Standard of Care
- Where
- 7 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Community-acquired Pneumonia (CAP)
TCM Cohort for Elderly CAP
This study evaluates the real-world clinical efficacy of traditional Chinese medicine (TCM) in elderly Community-acquired pneumonia (CAP) patients and explores syndrome characteristics and their associations with biomarkers.
- Trial name
- NCT07797686
- Testing
- Traditional Chinese medicine (TCM), Non-traditional Chinese medicine (non-TCM)
- Where
- China
- Volunteers
- 2,234 people, healthy volunteers welcome
- Sponsor
- Henan University of Traditional Chinese Medicine
HIV/AIDS and Infections, Drug Abuse
A Community-University Approach to Preventing HIV
Examine the feasibility and acceptability of delivering the S4E intervention to 20 African-American youths between the ages 16-21 in Flint, Michigan.
- Conditions
- HIV/AIDS and Infections, Drug Abuse, Adolescent Behavior, Drug Usage
- Trial name
- NCT03938077
- Testing
- Storytelling 4 Empowerment
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Covid19, Community-Acquired Respiratory Tract Infection
Non-invasive Biometric Monitoring in Nursing Homes to Fight COVID-19
Solving the problem of detecting asymptomatic carriers who can transmit infection is key to protecting vulnerable residents of nursing homes and assisted living facilities, to protecting frontline workers who care for them, and…
- Trial name
- NCT04548895
- Testing
- Observational measurement of biometric data. No change to health care provided.
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Health Stream Analytics, LLC