Clinical trials: Comparative Effectiveness Study
Dry Eye Syndrome
Efficacy Comparative Study Between Tears Again®, Opticol® and Optive®
Primary Purpose: To compare the efficacy in treating dry eye syndrome in contact lens wearers or computer users of Tears Again® versus Opticol® versus Optive® Secondary Purpose: Subjective evaluation of symptomatology Evaluation…
- Trial name
- NCT00893243
- Where
- Portugal
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Sao Sebastiao
Healthy Volunteers
Safety and Efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine for Facial Augmentation in Asian Population
The purpose of this study is to evaluate the safety and efficacy of Restylane Lidocaine and Restylane Perlane Lidocaine after the first and second treatment when used for facial augmentation in Asian population.
- Trial name
- NCT02565784
- Testing
- Restylane, Perlane
- Where
- 2 sites in Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Orthodontics
Comparative Study of Different Bone Grafts in Accelerating Tooth Movement
Objective: Periodontally accelerated osteogenic orthodontics(PAOO) will minimize treatment time. The current study will be carried to evaluate the effectiveness of different bone grafts with a modified, less invasive corticotomy…
- Trial name
- NCT02796911
- Testing
- Xenograft, Bioactive glass
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Anxiety, Behavior
Efficacy of Camouflaged Syringe vs Conventional Syringe
This study evaluates the efficacy of Camouflage syringe vs Conventional syringe in reducing Dental Anxiety and increasing behaviour rating.Half of the participants received local anesthesia using camouflaged syringe, while others…
- Trial name
- ECC (NCT03566212)
- Testing
- Conventional Syringe, Camouflage Syringe
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Cryotherapy Effect, Warts
Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment
This study aimed to study cost-effectiveness of EndWarts® FREEZE for wart treatment, compared to conventional liquid nitrogen cryotherapy
- Trial name
- NCT04781244
- Testing
- EndWarts® FREEZE, Liquid nitrogen
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hepatitis B
LT F-up Study 16-20 Yrs After Vaccine Dose of Hepatitis B With/Without HBIg in Newborns to HBeAg+ Mothers
To evaluate the persistence of anti-HBs antibodies up to 16, 17, 18, 19 and 20 years after administration of the first dose of the study vaccine.
- Trial name
- NCT00240526
- Testing
- Engerix™ -B, Hepatitis B immunoglobulin (HBIg)
- Where
- Thailand
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acne
Comparative Effectiveness Study of Spironolactone Versus Doxycycline for Acne
Acne is common illness of adolescents and young adults which is associated with substantial morbidity. While topical treatments are often sufficient for mild acne, moderate to severe acne often requires treatment with systemic…
- Trial name
- SD-ACNE (NCT04582383)
- Testing
- Spironolactone, Doxycycline Hyclate
- Where
- 18 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Bleeding
Studying Safety & Efficacy of Axiostat® Dressing in Acute Hemorrhage Due to Trauma-Comparative Study
The aim of this study was to evaluate the efficacy and safety to use external haemostatic between Axiostat® (Chitosan haemostatic dressing) and conventional cotton gauze dressing as a pre hospital acute hemorrhagic control in…
- Trial name
- NCT03035695
- Testing
- Axiostat®, Cotton Gauze
- Where
- India
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Axio Biosolutions Pvt. Ltd.
Dental Caries
Comparative Evaluation of Effectiveness of Hall Technique and Resin Modified Glass Ionomer Cement in Controlling Occlusoproximal Caries in Primary Molars in Children
•To investigate clinical and radiographic outcomes of Hall Technique and conventional restorative care using RMGIC in occulusoproximal carious lesions of primary molars in children.
- Trial name
- NCT04355000
- Testing
- Hall technique, RMGIC restoration
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Acne, Scar
Comparison of Efficacy Between Fractional Microneedling Radiofrequency and Bipolar Radiofrequency for Acne Scar
Compare the efficacy and safety profile of microneedling radiofrequency and that of bipolar radiofrequency treatment for acne scar.
- Trial name
- NCT02207738
- Testing
- microneedling radiofrequency device, bipolar radiofrequency
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Infant Development
Effects of an Infant Formula on Growth, Safety and Efficacy for Healthy Term Infants
The purpose of this study is to evaluate that a Cow's Milk Based Infant Formula A2 Containing Both OPO and CPP for healthy term infants supports age-appropriate growth.
- Trial name
- NCT04749290
- Testing
- Study Formula
- Where
- 2 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bunge Loders Croklaan
Cardiac Arrest (CA)
Hand vs. Foot Chest Compressions in Simulation
Cardiopulmonary resuscitation (CPR) is essential in the management of cardiorespiratory arrest (CA) to improve survival rates. High-quality chest compressions are the primary intervention to maintain circulation and oxygenation…
- Trial name
- NCT07074080
- Testing
- Performing chest compressions on a mannequin using the foot, Performance of standard chest compressions with the upper limbs.
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Head Lice, Pediculosis Capitis
A Clinical Trial to Evaluate Efficacy and Safety of a New Suffocating Head Lice Product.
The present study is set-up to compare in vivo clinical performance and safety of the test product (X92001752) versus 3 other pediculicides (2 medical devices and 1 conventional pesticide).
- Trial name
- NCT05378477
- Testing
- X92001752, RID Super Max Solution, Nix Crème
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
HIV Prevention
Optimizing Pre-Exposure Prophylaxis (PrEP) Among Latino Men Who Have Sex With Men (MSM) in Puerto Rico
To develop, assess and compare the effectiveness of a Motivational Interviewing Intervention for increasing Pre-Exposure Prophylaxis (PrEP) uptake among Latino eligible men in Puerto Rico.
- Trial name
- NCT05804461
- Testing
- Motivational Interviewing
- Where
- Puerto Rico
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Constipation
Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
Primary Objective: To evaluate the clinical efficacy of Naturetti (jelly sugar free) To test medication on subjects who suffer chronic functional constipation in 30 days use.
- Trial name
- NCT00931853
- Testing
- SENNA+CASSIA(Naturetti)
- Where
- Brazil
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Sanofi
Iron Overload Due to Repeated Red Blood Cell Transfusions, Thalassemia Majors (Beta-Thalassemia Major)
Evaluate the Efficacy and Safety of Irochel for the Management of Iron Overload in Thalassemia Patients in Comparison With Deferoxamine
This research study was an experimental, randomized, controlled clinical trial to evaluate the safety and efficacy of coded Unani formulation Irochel for the management of IOL due to repetitive blood transfusion in comparison…
- Trial name
- NCT07782931
- Testing
- Irochel, Deferoxamine
- Where
- Pakistan
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hamdard University
Coronavirus Infections, Vaccine
An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac)
An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac), Produced by FSBSI "Chumakov…
- Trial name
- NCT05407142
- Testing
- CoviVac vaccine (inactivated whole-virion concentrated purified) manufactured by FSBSI "Chumakov FSC R&D IBP RAS", The data from volunteers from the control group
- Where
- 10 sites in Russia
- Volunteers
- 29,000 people, healthy volunteers welcome
- Sponsor
- Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products
Impacted Third Molar Tooth, Impacted Molar
Different Oral Doses of Clindamycin in Preventing Post-operative Sequelae of Lower Third Molar Surgery
The objective of the study is to determine the effect of antibiotic prophylaxis with three different doses of clindamycin on preventing infection and other complications after surgical extraction of impacted mandibular third…
- Trial name
- NCT05268835
- Testing
- Dalacin C
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oral and Maxillofacial Surgery Clinic, Poland
Multimodal Analgesic Approach
IV vs Oral Acetaminophen in Spine Fusion Perioperative Care
The United States is currently experiencing an explosive opioid epidemic. In 2014 alone, 28,647 Americans died from an opioid associated overdose; the annual death toll has increased by over 300% since 2000.
- Trial name
- NCT03020875
- Testing
- Ofirmev, Per Os Acetaminophen
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
IUD Insertion
Usability, Safety and Efficacy of AspivixTM (Comparative Study)
Limited mobility of the uterine cervix and alignment with the vaginal canal is often required during insertion of an intrauterine contraceptive device (IUD).
- Trial name
- NCT04441281
- Testing
- Traction of the cervix for IUD insertion
- Where
- 2 sites in Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Aspivix SA