Clinical trials: Complex Symptom Disorders
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Chronic Periodontitis
Complex Phytoadaptogenes in Chronic Periodontitis Treatment.
A randomized controlled clinical trial was done to assess the periodontal status of the individuals baseline followed by by including chronotherapy with complex phytoadaptogens (CFA) into the non-surgical periodontal treatment…
- Trial name
- NCT04623164
- Testing
- Cocktail from complex phytoadaptogens (CFA), Standard non-surgical periodontal treatment (NSPT)
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vladikavkaz Scientific Center of the Russian Academy of Sciences
Parkinson Disease, Parkinson's Disease and Parkinsonism
Complex Eye Movements in Parkinson's Disease and Related Movement Disorders
Diagnosing Parkinson's disease (PD) depends on the clinical history of the patient and the patient's response to specific treatments such as levodopa.
- Conditions
- Parkinson Disease, Parkinson's Disease and Parkinsonism, Progressive Supranuclear Palsy, Corticobasal Degeneration
- Trial name
- NCT04925622
- Testing
- Complex eye movement exam
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Saccadous, Inc.
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Obesity, Insulin Resistance
Complex Effects of Dietary Manipulation on Metabolic Function, Inflammation and Health
The purpose of this research study is to 1) understand how some, but not all people with obesity develop obesity related conditions such as type 2 diabetes and cardiovascular disease, and 2) compare the effects of 3 popular…
- Trial name
- NCT02706262
- Testing
- Metabolically abnormal obese - Mediterranean diet, Metabolically abnormal obese - Low carbohydrate ketogenic diet, Metabolically abnormal obese - Plant-based, very-low-fat diet
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Premature Ventricular Complexes
Physical Impairments in Premature Ventricular Complex
Premature ventricular complexes may be observed in individuals without underlying disease due to factors such as physical inactivity, advanced age, smoking, male sex, and psychosocial disturbances, and in some cases may result in…
- Trial name
- NCT07396597
- Testing
- Physical Evaluations of Patients with Premature Ventricular Complex, Physical Evaluations of Healthy Individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Insulin Resistance, Impaired Glucose Tolerance
Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)
The purpose of this study is to investigate the effects of a fibre mixture added to a high-protein diet on metabolic, gut and brain health.
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, PreDiabetes, Overweight and Obesity
- Trial name
- DISTAL (NCT05354245)
- Testing
- Fibre supplement (potato-pectin), High-protein diet
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
PROM, Satisfaction, Patient
Assessment of the Humanisation of Care in Hospitals in Andalusia-Spain
Observational assessment through patient interviews of relational, structural and organisational aspects related to the humanisation of health care.
- Conditions
- PROM, Satisfaction, Patient, Satisfaction, Personal, Stress
- Trial name
- HUMANCUIDA (NCT06174844)
- Testing
- No intervention applied
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Neuropathic Pain
Evaluation of an ATP-Containing Parenteral Vitamin B Complex in Patients With Symptomatic Diabetic Polyneuropathy
Epinosine B Forte ampoule is an intramuscular injectable supplement containing adenosine triphosphate (ATP), Cocarboxylase (vitamin B1 derivative), vitamin B12, and nicotinamide (vitamin B3).
- Trial name
- NCT07296354
- Testing
- adenosine triphosphate, Vitamin B Complex
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Egyptian International Pharmaceutical Industries Co
Epilepsy
Role of Hormones in Susceptibility to Seizures in Women With Epilepsy
This study will measure and compare hormone levels in women with catamenial epilepsy (epilepsy in which seizures are more frequent during menstrual periods), women with seizures not related to their menstrual cycle, and normal…
- Trial name
- NCT00044252
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Adenomyosis of Uterus
Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical Symptoms
The goal of this study/research is to assess the relationship between ultrasound features of the myometrium suggestive of adenomyosis and clinical symptoms of adenomyosis and to establish a reporting system for adenomyosis…
- Trial name
- MUSA3 (NCT07397715)
- Where
- 5 sites in Belgium, Poland and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss GO Trial Group
Obesity
Energy Balance Weight Regulation Study
The purpose of this study is to test the hypothesis that a low-carbohydrate diet will impact hormones and other factors that regulate appetite and energy balance, and result in lower energy intake and greater weight loss, than a…
- Trial name
- BALANCE (NCT00619008)
- Testing
- Ad libitum low carbohydrate diet, Ad libitum High Complex Carbohydrate Diet, Energy-restricted high complex carbohydrate diet
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Analgesia
Epidural Anesthesia /Analgesia Versus PCA for Laparoscopic Complex Ventral Hernia Repair: A Randomized Controlled Trial
We plan to demonstrate the superiority of epidural anaesthesia/analgesia in repairs of large ventral hernias as compared with a conventional narcotic analgesia regimen. We hypothesize that: 1.
- Trial name
- NCT00529074
- Testing
- Epidural Catheter for Analgesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Ventricular Premature Complexes
Relativity Study Between Idiopathic Ventricular Arrhythmia and Sex Hormone Levels in Different Stages of Menstrual Cycle
The purpose of this study is to determine whether the occurrence of idiopathic right ventricular outflow tract(RVOT) arrhythmia is relative to sex hormone levels in different stages of female menstrual cycle
- Trial name
- NCT00606736
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Harbin Medical University
Ventricular Premature Complexes, Atrial Premature Complexes
Oral Magnesium Supplementation in Athletes With Premature Ventricular Contractions or Premature Atrial Contractions.
Magnesium is a mineral which is essential to many of the processes which happen in the body. This includes normal function of muscles; including the heart.
- Trial name
- NCT04186728
- Testing
- Magnesium glycinate
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Premature Ventricular Complexes, Diet Quality
Premature Ventricular Complex and Diet Inflamatuar Index
The aim of this study is to evaluate differences in energy, macro- and micronutrient intakes, dietary characteristics, quality of life, and biochemical parameters between individuals with and without premature ventricular…
- Conditions
- Premature Ventricular Complexes, Diet Quality, Biochemical Markers, Life Quality
- Trial name
- PVT (NCT07870109)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Healthy Volunteers
Advanced Clinical Practitioners in the ED
This study is designed to understand better how nurses, paramedics, and other healthcare professionals who have completed extra training to become Emergency Care Advanced Clinical Practitioners (EC-ACPs) work in emergency…
- Trial name
- NCT06355648
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Learning Disturbance
Complex Motor Learning With Motor Imaginary
Subjects participate in a motor learning training with a special bicycle. The experimental group proceed with 15 minutes of physical training with the bicycle and 15 minutes of rest where they use motor imaginary.
- Trial name
- NCT02999516
- Testing
- Motor imaginary, Non Motor imaginary, tDCS
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
COPD
Assessment of Severity and Prognosis in Elderly Patients With COPD and Complex Chronic Comorbidities
Cigarette smoking, the major risk factor for Chronic Obstructive Pulmonary Disease (COPD), causes systemic effects, such as systemic cellular and humoral inflammation, that could substantially contribute to the development of…
- Trial name
- NCT01893918
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia