Clinical trials: Complication, Postoperative
Surgical Site Infection, Cosmetic Appearance of Cesarean Scar
Prospective Study on Cesarean Wound Outcomes
This study will investigate whether the placement of silver impregnated dressings beginning in the OR will improve wound healing in patients undergoing cesarean delivery compared to traditional Telfa pads.
- Conditions
- Surgical Site Infection, Cosmetic Appearance of Cesarean Scar, Post Operative Pain
- Trial name
- NCT01697748
- Testing
- Silver-impregnated dressing, Telfa pad dressing
- Where
- 3 sites in United States
- Volunteers
- 660 people
- Sponsor
- University of South Florida
Postoperative Pain
Transversus Abdominis Plane Catheter: a Study of Method
Major abdominal surgery is associated with postoperative pain. Transversus Abdominis Plane(TAP) block has been shown to reduce pain and opioid-requirements after abdominal surgery.
- Trial name
- NCT01395043
- Testing
- Placing bilateral TAP-catheters preoperatively, Bupivacain 2.5 mg/ml with epinephrine bolus in TAP-catheters
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Aalborg University Hospital
Surgery, Delirium
Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients
This study aims to assess the feasibility, acceptability, and safety of using ReCognitionVR virtual reality-based software in older surgical patients.
- Conditions
- Surgery, Delirium, Delirium, Post-Operative
- Trial name
- NCT06232317
- Testing
- Virtual Reality Software, Traditional Orientation Methods
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Methodist Hospital Research Institute
Postoperative Pain
A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty
The purpose of this study is to determine wether ketorolac is effective in the treatment of postoperative pain after total knee arthroplasty
- Trial name
- NCT00868348
- Testing
- Ketorolac, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Hemorrhage, Surgical, Blood Loss, Surgical
Safe and Timely Antithrombotic Removal - Ticagrelor (STAR-T)
Prospective, multi-center, double-blind, randomized pivotal trial to evaluate the safety and effectiveness of the DrugSorb-Antithrombotic Removal (ATR) system for intraoperative removal of ticagrelor in patients undergoing urgent…
- Conditions
- Hemorrhage, Surgical, Blood Loss, Surgical, Blood Loss, Postoperative, Hemorrhage Postoperative
- Trial name
- STAR-T (NCT04976530)
- Testing
- DrugSorb-ATR system
- Where
- 29 sites in United States, Canada
- Volunteers
- 140 people
- Sponsor
- CytoSorbents, Inc
Prosthesis Failure
Investigation on Failure Time Analysis of a New TPE Material in the Iceform Liner
Durability evaluation of a new material blend in the Iceform liner and Iceform sleeve.
- Trial name
- NCT05040165
- Testing
- Iceform liner and sleeve
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Össur Iceland ehf
Short Bowel Syndrome
An Extension Study of Teduglutide in Japanese Participants With Short Bowel Syndrome Who Completed 24 Weeks of Treatment in SHP633-306 or TED-C14-004
The purpose of this clinical study is to evaluate the long-term safety and efficacy of teduglutide in Japanese participants with PN/IV (parenteral nutrition/intravenous)-dependent SBS (short bowel syndrome) who completed…
- Trial name
- NCT03596164
- Testing
- Teduglutide, Syringe, Needle
- Where
- 5 sites in Japan
- Volunteers
- 11 people
- Sponsor
- Takeda
Abdominal Wall Hernia, Pancreatic Diseases
IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population
Number of patients with unsatisfactory pain relief defined as average visual analog scale (VAS) more than 5 with or without requirement of IVPCA for pain relief during the first 48 hours postoperative period will be compared…
- Conditions
- Abdominal Wall Hernia, Pancreatic Diseases, Bowel Disease, Gastric Disease
- Trial name
- NCT03198871
- Testing
- Acetaminophen Injectable Product, Sodium Chloride 0.9%, Intravenous
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kathirvel Subramaniam
Renal Calculus, Kidney Stones
Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone disease.
- Trial name
- NCT00765128
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Pain, Postoperative, Burns
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
Donor site pain study comparing post-operative donor site pain and opioid consumption after use of Lidocaine, Liposomal Bupivicaine or regional nerve block for split thickness skin graft harvesting in patients with less than 20%…
- Trial name
- NCT03854344
- Testing
- Lidocaine Hydrochloride, Liposomal bupivacaine, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Kansas Medical Center
Postoperative Pain, Total Knee Replacement
Treatment of Post-Operative Pain Following Orthopedic Surgery With SPRINT® Peripheral Nerve Stimulation (PNS) System
The purpose of this study is to gather information about how knee pain changes when small amounts of electricity are delivered to the nerves in the leg.
- Conditions
- Postoperative Pain, Total Knee Replacement, Total Knee Arthroplasty, Partial Knee Replacement
- Trial name
- NCT04341948
- Testing
- SPRINT Peripheral Nerve Stimulation (PNS) System
- Where
- 10 sites in United States
- Volunteers
- 56 people
- Sponsor
- SPR Therapeutics, Inc.
Residual Neuromuscular Blockade
Electromyographic and Acceleromyographic Monitoring in Restricted Arm Movement Surgical Setting
Researchers are comparing the ease of use and repeatability of the force vs electrical activity produced by a muscle after it has undergone nerve stimulation during a surgical procedure in which the patients' arm movement is…
- Trial name
- NCT04352140
- Testing
- Tetragraph, ToFscan
- Where
- 3 sites in United States, France and 1 more
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Infection, Surgery
Topical Vancomycin for Neurosurgery Wound Prophylaxis
This study is a collaboration between New York Presbyterian (NYP)-Columbia and NYP-Cornell that seeks to evaluate the use of topical vancomycin and its reduction on surgical site infection (SSI) in neurosurgical procedures.
- Conditions
- Infection, Surgery, Nervous System Diseases
- Trial name
- Vanguard (NCT02284126)
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 1,103 people
- Sponsor
- Columbia University
Post Operative Pain, Nausea
Effects of Perioperative Intravenous Dexamethasone on Pain in Out Patient Knee Surgery
The purpose of the study is to determine the opiate sparing effects of intravenously administered dexamethasone in outpatient knee surgery. Dexamethasone is a glucocorticoid with well known antiemetic effects.
- Trial name
- NCT01149616
- Testing
- Dexamethasone 8mg iv x1
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Delayed Emergence From Anesthesia, Postoperative Delirium
Trajectory of Recovery in the Elderly
The purpose of this study is to understand how elderly individuals regain their cognitive skills following general anesthesia. The investigators will compare an age stratified group of volunteers who will be evaluated with a…
- Conditions
- Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
- Trial name
- TORIE (NCT02275026)
- Testing
- Functional magnetic resonance imaging
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Wound Infection Due to Staphylococcus Aureus, MRSA Infection of Postoperative Wound
S. Aureus Screening and Decolonization
Staphylococcus aureus (SA) healthcare-associated infections (HAI) cause significant morbidity and mortality. SA causes 15% of all HAI and 30% of surgical site infections (SSIs).
- Trial name
- NCT02182115
- Testing
- antiseptic bundle, standard of care
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Delirium, Postoperative Cognitive Dysfunction
Rivastigmine in the Treatment of Postoperative Delirium: a Pilot Clinical Trial
The purpose of this study is to determine whether preoperative administration of Rivastigmine prevents the incidence of postoperative delirium in patients undergoing major surgery as well as postoperative cognitive dysfunction.
- Trial name
- NCT00835159
- Testing
- Rivastigmine Patch
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Vasectomy, Pain, Postoperative
Virtual Reality Technology for Vasectomy Pain Modulation
This study will evaluate whether or not wearing a virtual reality (VR) headset reduces pain and anxiety in patients undergoing vasectomy.
- Conditions
- Vasectomy, Pain, Postoperative, Anxiety Postoperative
- Trial name
- NCT05591274
- Testing
- SmileyScope Virtual Reality Headset
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Head and Neck Neoplasms
LigaSure Small Jaw® Versus Conventional Neck Dissection in Head and Neck Cancer Patients
The aim of this prospective randomized study was to investigate if the LigaSure vessel sealing system can reduce the operation duration and the postoperative drainage amount in patients undergoing neck dissection.
- Trial name
- NCT02597582
- Testing
- Neck dissection
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Taichung Veterans General Hospital
Colonic Neoplasms, Rectal Neoplasms
NITI CAR27 (ColonRing) Compression Anastomosis in Colorectal Surgery
After resection of diseased segments of the large intestine, the continuity of the intestine has to be restored. This can be done by suturing or with so called stapling devices.
- Conditions
- Colonic Neoplasms, Rectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases
- Trial name
- NCT01056913
- Testing
- Compression Anastomosis Device, follow-up colonoscopy
- Volunteers
- 62 people
- Sponsor
- St John of God Hospital, Vienna