Clinical trials: Complication Laparoscopic Cholecystectomy
Pain, Postoperative
Effective Postoperative Pain Relief After Laparoscopic Cholecystectomy With TENS
The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) treatment for first line of treatment compared with conventional treatment with opioids on pain relief and time spent time in the…
- Trial name
- NCT04114149
- Testing
- TENS (transcutaneous electrical nerve stimulation), iv opioid
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Göteborg University
Cholelithiasis
Effect of Erector Spinae Plane Block on Postoperative Respiratory Function After Laparoscopic Cholecystectomy
Postoperative pulmonary dysfunction is frequently observed after laparoscopic abdominal surgery due to the combined effects of general anesthesia, pneumoperitoneum, diaphragmatic dysfunction, and postoperative pain.
- Trial name
- ESP-LC (NCT07478601)
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Uludag University
Cholecystectomy, Laparoscopic, Anesthesia, General
Effect of Pupilometer Guided Analgesia on Postoperative Pain
In this study, the investigators measure a pupil size every 5 minutes during the operation in patients undergoing laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Cholecystectomy, Laparoscopic, Anesthesia, General, Reflex, Pupillary
- Trial name
- PUPIL_pain (NCT03794271)
- Testing
- Pupilometer guided anesthesia, SPI guided anesthesia
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Daegu Catholic University Medical Center
Postoperative Pain
Dose Esmolol Infusion Have an Adjuvant Effect to TAP Block for Pain Control in Laparoscopic Cholecystectomy.
Pain after laparoscopy differs considerably from that seen after laparotomy. Laparotomy results mainly in parietal pain (abdominal wall), where as Pain in laparoscopy results from stretching of the intra-abdominal cavity…
- Trial name
- NCT04752111
- Testing
- Esmolol
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Airway Edema, Perioperative Complication
Ultrasound Assessment of Airway Edema During Laparoscopic Cholecystectomy
This prospective, double-blind, randomized clinical trial aims to investigate the development of airway edema associated with intra-abdominal pressure during laparoscopic cholecystectomy.
- Conditions
- Airway Edema, Perioperative Complication, Pneumoperitoneum
- Trial name
- NCT07021482
- Testing
- 10 mmHg Pneumoperitoneum, 14 mmHg Pneumoperitoneum
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Engin Çetin
Postoperative Pain
Comparison of Analgesic Efficacy of US Guided ESP Block With Port Site Infiltration Following Laparoscopic Cholecystectomy
To compare the efficacy of ultrasonography (USG)-guided bilateral Erector spinae plane block (ESPB) with port-site infiltration using bupivacaine for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis…
- Trial name
- NCT04167176
- Testing
- Erector spinae plane block, Port site infiltration, Ultrasound machine (Mindray DP 9900 plus; Mindray Bio-Medical Electronics, Shenzhen, China)
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Postoperative, Pain
Lidocaine Patch for Postoperative Analgesia After Laparoscopic Cholecystectomy
The investigators hypothesized that application of a 5% lidocaine patch would be associated with reduced pain scores after operation compared with placebo patch in patients undergoing laparoscopic cholecystectomy.
- Trial name
- NCT01485939
- Testing
- 5% lidocaine patch
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV)
Predictive Role of HRV for PONV in Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) are among the most common complications following general anesthesia (GA), significantly affecting patient comfort and recovery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV), Laparoscopic Cholecystectomy
- Trial name
- NCT06948708
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Pain, Postoperative
Dexmedetomidine Infusion as an Analgesic Adjuvant During Laparoscopic Cholecystectomy
The aim of this study was to evaluate efficacy and safety of dexmedetomidine infusion during laparoscopic cholecystectomy. The randomized, single-center, controlled study was carried out from May 2016 to June 2017 at department…
- Trial name
- NCT03211871
- Testing
- Dexmedetomidine, Normal Saline Flush, 0.9% Injectable Solution_#1
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Bogomolets National Medical University
Postoperative Pain, Opioid Consumption
Lidocaine and Analgesia After Laparoscopic Cholecystectomy
The purpose of this study is to evaluate how effective is the intraoperative use of lidocaine to attenuate postoperative pain and opioids consumption after laparoscopic cholecystectomy
- Trial name
- NCT03620591
- Testing
- Lidocaine
- Where
- Greece
- Volunteers
- 98 people
- Sponsor
- Larissa University Hospital
Postoperative Pain
A Comparison of Laparoscopic Cholecystectomy Versus Ultrasonic Dissection Assisted Minilaparotomy Cholecystectomy
Minilaparatomy cholecystectomy with ultrasonic dissection (UsD) is rarely considered and therefore we investigate here the contributions of UsD in early recovery.
- Trial name
- MC-UsD (NCT01723540)
- Testing
- Minilaparotomy vs laparoscopy
- Where
- Finland
- Volunteers
- 88 people
- Sponsor
- Kuopio University Hospital
Acute Pain, Postoperative Pain
Comparison of the Effectiveness of Preemptive Paracetamol and Ibuprofen in Acute Postoperative Pain
This study will evaluate two different analgesic regimen used for acute postoperative pain.
- Trial name
- NCT03063658
- Testing
- Paracetamol, Ibuprofen 800 mg
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Postoperative Pain
COMPARISON OF INTRAOPERATIVE LOCAL ANESTHETIC APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN LAPAROSCOPIC CHOLECYSTECTOMY PATIENTS
Since 1987, laparoscopic cholecystectomy has become the standard procedure for gallbladder stones and lesions. Complications due to improvements in laparoscopy and increased surgical experience have decreased day by day, but…
- Trial name
- NCT03790007
- Testing
- Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Postoperative Nausea, Postoperative Vomiting
Comparison of IV Fluid Loading and Ondansetron in Reduction of PONV After LC
This study is designed to examine the incidence of postoperative nausea and vomiting during 24 hours after elective laparoscopic cholecystectomy in patients receiving preoperative intravenous fluid loading (group F), ondansetron…
- Conditions
- Postoperative Nausea, Postoperative Vomiting, Postoperative Nausea and Vomiting
- Trial name
- NCT03141645
- Testing
- Fluid loading, Ondansetron
- Where
- Thailand
- Volunteers
- 171 people
- Sponsor
- Siriraj Hospital
Post Operative Pain
Comparison Between Bupivacaine and Bupivacaine- Dexamethasone QLB for Postoperative Analgesia
The objective of this study is to assess the analgesic sparing effect of adding Dexamethasone to Bupivacaine in Quadratus lumborum block in patients undergoing Laparoscopic cholecystectomy under general anesthesia.
- Trial name
- NCT05918796
- Testing
- Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nausea and Vomiting, Postoperative
Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
- Trial name
- NCT04899817
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acute Postoperative Pain, Chronic Postoperative Pain
Menstrual Phase and Postoperative Pain
Fluctuations of female sex hormones during the menstrual cycle influence pain perception. Endogenous pain is pronounced in the follicular phase of the menstrual cycle.
- Trial name
- NCT02137135
- Testing
- HAD scale, The SF 12 test, Visual analogue score
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Postoperative Pain
Comparison of the Quadratus Lumborum Block With the Transversus Abdominis Plan Block
In this study, investigators aimed to compare the Quadratus Lumborum Block and the Transversus Abdominis Plan Block for postoperative pain control after laparoscopic cholecystectomy
- Trial name
- NCT03112915
- Testing
- quadratus lumborum block, Transversus abdominis plan block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kecioren Education and Training Hospital
Cholecystectomy, Postoperative Pain
Analgesic Effect of Quadratus Lumborum Block Application After Laparoscopic Cholecystectomy Surgery
Laparoscopy is frequently used today for intraabdominal operations. Laparoscopic procedure has become the treatment of choice for many patients with symptomatic cholelithiasis.
- Conditions
- Cholecystectomy, Postoperative Pain, Nerve Block
- Trial name
- NCT03308955
- Testing
- Tramadol, Ultrasound guided Quadratus Lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Post Operative Pain
Trial of Extended Release Bupivacaine for Pain Relief After Surgery
This is a research study of SABER® -Bupivacaine, an experimental medication designed to reduce pain for up to 3 days after surgery.
- Trial name
- PERSIST (NCT02574520)
- Testing
- SABER-Bupivacaine (Part 1), SABER-Bupivacaine (Part 2), Bupivacaine HCl
- Where
- 21 sites in United States
- Volunteers
- 399 people
- Sponsor
- Durect