Clinical trials: Comprehensive Care, active
Contraceptive Behavior, Self Administration
Impact of Self-Care Family Planning Services on Health and Development in South Sudan (Family Planning Impact Lab)
Since 2019, the International Rescue Committee (IRC) has led family planning programming under the Women's Integrated Sexual Health (WISH) program, funded by the United Kingdom's Foreign, Commonwealth, and Development Office.
- Trial name
- FPIL (NCT07888296)
- Testing
- Self-Managed Contraceptive Care, Standard Family Planning Services (WISH-2)
- Where
- South Sudan
- Volunteers
- 2,736 people, healthy volunteers welcome
- Sponsor
- Guttmacher Institute
Solid Neoplasms, Solid Tumors
Integrating Geriatric 8 (G8) Screening and Cancer and Age Research Group (CARG) Toxicity Assessment Score Into Routine Care for Older Adults With Cancer
This study evaluates whether using specialized geriatric screening and toxicity prediction tools can help oncologists personalize chemotherapy dosing and reduce severe side effects in older adults with solid cancers.
- Conditions
- Solid Neoplasms, Solid Tumors, Chemotherapy-Induced Toxicity
- Trial name
- NCT07837505
- Volunteers
- 100 people
- Sponsor
- Assiut University
Critically Ill, Acute Respiratory Failure
The EXCEL Registry of Patients Requiring ECMO
ECMO is associated with significant costs, risks and requires specialist training and expertise. EXCEL is a novel, high-quality, detailed prospective registry of patients requiring ECMO in Australia and New Zealand.
- Conditions
- Critically Ill, Acute Respiratory Failure, Acute Heart Failure, Cardiac Arrest
- Trial name
- NCT03793257
- Where
- 29 sites in Australia, New Zealand
- Volunteers
- 3,000 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Surgery, Aging
Preparing Older Adults for Major Surgery With Preoperative Comprehensive Geriatric Assessments
The researchers will conduct observations, interviews, and focus groups with clinicians, staff and patients of the Perioperative Optimization of Senior Health (POSH) clinic, which conducts preoperative comprehensive geriatric…
- Conditions
- Surgery, Aging, Health Care Utilization, Frailty
- Trial name
- NCT06184919
- Testing
- Process Mapping: Observations, Process Mapping: Interviews, Process Mapping: Focus Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Metastatic Prostate Cancer
TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer
TOPCOP3 is a pilot factorial RCT of geriatric assessment and management, remote symptom monitoring, both interventions or neither, accompanied by an embedded process evaluation.
- Trial name
- TOPCOP3 (NCT05582772)
- Testing
- GA+M Intervention, RSM intervention, GA+RSM intervention
- Where
- 3 sites in Canada
- Volunteers
- 168 people
- Sponsor
- University Health Network, Toronto
Sleep Disordered Breathing (SDB)
Comprehensive Care of Sleep Disordered Breathing
The Comprehensive Care of Sleep Disordered Breathing study (Care-SDB) is a prospective, multi-center, registry-based cohort study designed to investigate the integrated management of sleep-disordered breathing (SDB).
- Trial name
- Care-SDB (NCT07339371)
- Testing
- Clinical Management for SDB
- Where
- China
- Volunteers
- 11,100 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Metastatic Breast Cancer
Evolution of the Therapeutic Care in Metastatic Breast Cancer From 2008
The Epidemiological Strategy and Medical Economic (ESME) Breast cancer Database is a multicenter real life database using a retrospective data collection process across 18 French comprehensive cancer centers (FCCC) spread over 20…
- Trial name
- ESME-MBC (NCT03275311)
- Where
- 20 sites in France
- Volunteers
- 42,000 people
- Sponsor
- UNICANCER
Frailty, Comprehensive Geriatric Assessment
The Impact of Domiciliary Versus 'Hub' Based Comprehensive Geriatric Assessment on Clinical and Process Outcomes Among Older Adults Attending Community Specialist Teams: a Randomised Controlled Trial.
The investigators plan to implement a randomised controlled trial to examine the impact of domiciliary (home based) versus 'hub-based' Comprehensive Geriatric Assessment (CGA) on clinical and process outcomes among older adults…
- Conditions
- Frailty, Comprehensive Geriatric Assessment, Older Adults, Domiciliary Care
- Trial name
- NCT06205238
- Testing
- CGA
- Where
- Ireland
- Volunteers
- 106 people
- Sponsor
- University of Limerick
Palliative Care, Withdrawal of Life Support
End-of-life Care in Mechanically Ventilated Patients: Impact of a Comprehensive Palliative Care Protocol in the Intensive Care Setting
The ARREVE-3 trial will evaluate whether a structured palliative care protocol can improve end-of-life management for mechanically ventilated ICU patients in whom a decision to withdraw life-sustaining therapies has been made.
- Conditions
- Palliative Care, Withdrawal of Life Support, Intensive Care Medicine, Sedation
- Trial name
- ARREVE-3 (NCT07368010)
- Testing
- Protocol for palliative care and life-support withdrawal
- Where
- France
- Volunteers
- 720 people
- Sponsor
- Nantes University Hospital
Migraine, Migraine With Aura
A Comprehensive Digital Care Program for Migraine Management
This study evaluates the clinical effectiveness of the Enso for Migraine program, a comprehensive digital care program combining an FDA-cleared neuromodulation wearable device (Enso), personalized exercise therapy, and a…
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- NCT07642414
- Testing
- Neuromodulation Wearable Device, Migraine Digital Care Program
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Hinge Health, Inc
Frail Elderly
Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) for Frail Older Adults in Primary Care
Frailty is a multidimensional clinical syndrome associated with increased vulnerability to adverse health outcomes in older adults.
- Trial name
- FRAIL+AP (NCT07643064)
- Testing
- FRAIL+AP Program, Usual Care
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Alberto Bermejo Franco
Female Infertility, Reproductive Disorders
Effect of Comprehensive Spa Rehabilitation on Female Infertility: A Clinical Study in Adult Women (Infertility-Spa)
This is a prospective, single-arm, pretest-posttest study evaluating the effects of a 21-day comprehensive spa treatment (Komplexní lázeňská léčebně rehabilitační péče, KLP) on female infertility at spa facility in Františkovy…
- Conditions
- Female Infertility, Reproductive Disorders, Recurrent Pregnancy Loss
- Trial name
- NCT07542600
- Testing
- Comrehensive Spa Treatment (KLP)
- Where
- Czechia
- Volunteers
- 55 people
- Sponsor
- Institute of Spa and Balneology, public research institution
Lung Cancer, Gastro-intestinal Cancer
The SOAR Study: a Study of Geriatric Assessment and Exercise for Older Adults and Their Support Person
Phase 2 randomized controlled study using a waitlist control group. The study also has a single arm pre-post test 12-week chair-based exercise arm for those who have received the geriatric assessment in the older adults with…
- Conditions
- Lung Cancer, Gastro-intestinal Cancer, Genito-Urinary Cancer, Breast Cancer
- Trial name
- SOAR (NCT05509751)
- Testing
- GAM, exercise, health education, online chair-based exercise combined with health education
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Martine Puts
Post Partum Depression
Screening for Postpartum Depression Using EPDS and HAM-D in Mothers Within 72 Hours After Delivery at a Tertiary Care Center (SOS-Mamma Study)
Postpartum depression (PPD) is one of the most common complications affecting maternal mental health after childbirth, with an estimated prevalence of 10-20% in high-income countries.
- Trial name
- SOS-Mamma (NCT07025902)
- Testing
- Standardized Psychological Screening Using EPDS and HAM-D
- Where
- Italy
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Dementia
The Effect of a Comprehensive Dementia Education Program on Improving Attitudes Toward People Living With Dementia
This randomized controlled trial focuses on Indonesian nursing students and examines the effectiveness of virtual reality (VR) dementia education programs. The study addresses the following research questions: 1.
- Trial name
- VReducationRCT (NCT07265856)
- Testing
- Comprehensive VR Program, Conventional Lecture Program (Non-VR)
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Amyloidosis in Transthyretin (TTR), Amyloidosis, Familial
Comprehensive Program for Hereditary Transthyretin Amyloidosis
The Comprehensive Program for Hereditary Transthyretin Amyloidosis describes a prospective observational study focused on understanding hereditary transthyretin amyloidosis (ATTR), a progressive and potentially fatal condition…
- Trial name
- NCT07213297
- Testing
- clinical assessments and complementary examinations
- Where
- Argentina
- Volunteers
- 20 people
- Sponsor
- Hospital de Alta Complejidad en Red
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Comprehensive Care, Quality of Care
Comprehensive Care Community and Culture Study
This randomized trial is evaluating whether socioeconomically disadvantaged Medicare patients at increased risk of hospitalization experience fewer hospitalization if those patients are offered care in: 1) ACCT, where patients…
- Conditions
- Comprehensive Care, Quality of Care, Medicare, Cost of Care
- Trial name
- NCT04489693
- Testing
- Ambulatory Care Coordinator Team (ACCT), Comprehensive Care Physician Program (CCP), Comprehensive Care Community & Culture Program (C4P)
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Chicago
Miscarriage in First Trimester
Comprehensive Assessment of First Trimester Pregnancy Loss
The FIRST-CARE Study is a prospective research project conducted at Hospital de la Santa Creu i Sant Pau (Barcelona, Spain), aimed at better understanding the causes and consequences of first-trimester pregnancy loss…
- Trial name
- FIRST-CARE (NCT07293819)
- Where
- 2 sites in Spain
- Volunteers
- 225 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Arrhythmia
Comprehensive Biomarker ProfiliNg in PatieNts With VEntriCular TachyCardia, PremAtuRe VEntricular Contractions, and AVNRT
To systematically evaluate multiple biomarkers in patients ventricular tachycardia (VT), premature ventricular contractions (PVC), atrioventricular nodal reentrant tachycardia (AVNRT) undergoing catheter ablation to elucidate…
- Trial name
- CONNECT-CARE (NCT07389928)
- Volunteers
- 200 people
- Sponsor
- University of Luebeck