Clinical trials: Conditioning
Healthy
The Effects of a Moderate Intensity Training Program Versus a High Intensity Training Program on Central Pain Processing
Previous studies have shown that healthy individuals who take more steps per day and who spend more time on moderate- to vigorous-intensity activities exhibit better pain inhibition and less pain facilitation.
- Trial name
- ChronicPA-PAIN (NCT06207422)
- Testing
- Moderate intensity training program, High intensity training program
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Ghent
Starvation
Effects of Glutamine on Gastric Emptying
Surgical patients are usually starved for 8 hours before operation in order to ensure the stomach is empty and thus reduce the chances of vomiting during the anaesthetic.
- Trial name
- NCT00943020
- Testing
- Nutricia PreOp nutritional supplement, Lipid, Glutamine
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Stroke, Stroke, Ischemic
Ischemic Conditioning Improves Walking Function Post Stroke
This innovative study will address scientific and clinical areas relatively unexplored in chronic stroke that could lead to greater recovery of walking.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Cardiovascular
- Trial name
- NCT04038697
- Testing
- Ischemic Conditioning, Treadmill Training
- Where
- 2 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Stroke, Acute
Exercise and RIC and TCD
The first week after a stroke is a particularly important time, as improving blood flow may limit secondary ischaemic damage to the brain and help reduce the overall burden neurological injury and future disability.
- Trial name
- NCT03968068
- Testing
- Exercise Procedure, Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Elderly, Hypertension
Unsupervised Physical Activity in Elderly
To evaluate safety and the effects of a unsupervised physical activity program (USPAP) over blood pressure (BP), physical fitness (PF) and quality of life (QL) of elderly hypertensive patients.
- Conditions
- Elderly, Hypertension, Physical Conditioning
- Trial name
- NCT02976506
- Testing
- Unsupervised exercise program, Physical fitness and quality of life
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Obsessive-Compulsive Disorder
The Neurocircuitry of Relief During Avoidance Learning in Patients With Obsessive-compulsive Disorder
To investigate the neuro-mechanisms underpinning persistent avoidance in OCD patients
- Trial name
- AvoidOCD (NCT04685018)
- Testing
- fMRI acquisition
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Healthy Adult
Exploring Pain Modulation With TMS and Repeated Pain Conditioning in Healthy Individuals
Conditioned pain modulation (CPM) is the behavioral measure of diffuse noxious inhibitory control (DNIC), an endogenous pain inhibitory pathway in which pain inhibits pain.
- Trial name
- NCT06726018
- Testing
- Conditioned Pain Modulation (CPM)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Priyanka Rana, PT, MPT, PhD
Healthy, Spastic Hemiparesis
Soleus Loading Response During Walking
Stroke survivors experience motor deficits, weak voluntary muscle activations, and low weight-bearing capacity that impair ambulation.
- Conditions
- Healthy, Spastic Hemiparesis, Stroke
- Trial name
- NCT05436366
- Testing
- Soleus loading response in able-bodied participants, Soleus loading response in participants with hemiparesis
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Victor H. Duenas
Young Adults, Performance
Effects of Pilates Stretching on Flexibility, Strength, Power and Muscular Endurance
Introduction: The practice of stretching is commonly used in the preparation of activities and/or physical exercises that require some component of flexibility, strength, endurance and muscle power.
- Conditions
- Young Adults, Performance, Exercise
- Trial name
- NCT05538520
- Testing
- Traditional Pilates, Pilates without stretching
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Neural Dynamics of the Acquisition and Retention of Fear Learning and Active Avoidance Learning
Use Electroencephalogram to Study Neural Dynamics of Fear Conditioning and Avoidance Learning Circuit in Humans
The purpose of this study is to examine which event-related potentials (ERPs) and event-related oscillations (EROs) are associated with fear conditioning, avoidance learning, and memory recall for fear and avoidance, where are…
- Trial name
- NCT06240052
- Testing
- Conditioning and active avoidance paradigm (CAAP)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Hearing Loss, Noise-Induced
Does Sound Conditioning Protect Against Temporary Hearing Damage
This research project will contribute to the research surrounding the effect on the ear after noise exposure. This ever-growing field of research has never been more applicable than now with the increase of recreational noise…
- Trial name
- NCT03878875
- Testing
- Session One Test Battery, Session Two Test Battery, Session Three Test Battery
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Aortic Dissection
Cerebral and Spinal Protection of Xenon Post-conditioning in Patients Undergoing Aortic Dissection Repair
With more and more people developing hypertension and atherosclerosis, the morbidity rate of Acute Aortic Dissection（AAD） has been increasing. Emergency surgery is the main treatment for Acute Aortic Dissection.
- Trial name
- NCT02774096
- Testing
- xenon
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Physical Conditioning
Taxi STEP (Social Networks, Technology, and Exercise Through Pedometers)
This study is divided into four groups. Group 1 includes Health Fairs implemented at NYC taxi garage bases and airport taxi holding lots and pedometers.
- Trial name
- NCT03010163
- Testing
- Health Fair, Pedometer, Text Messaging
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy
Dynamics of Fatigue and Recovery in MMA Training
This observational study aims to understand how strength and conditioning training impacts biochemical and psychological markers of fatigue and recovery in mixed martial arts (MMA) athletes.
- Trial name
- NCT06709599
- Testing
- Three-Week Strength and Conditioning Program
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Healthy Young Adults
Remote Ischemic Conditioning and Spinal Reflex Modulation
Remote ischemic conditioning (RIC) is a clinically feasible method that protects distant organs from severe injury through brief, sub lethal periods of ischemia followed by re-perfusion.
- Trial name
- NCT06860464
- Testing
- Remote Ischemic Condtioning (RIC), Balance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Obesity
Fear Conditioning Paradigm in Obesity
Fear processing in obesity and specifically the ability to i) learn and remember threatening stimuli, and ii) implicitly (i.e., unconsciously) and explicitly (consciously) discriminate them from neutral ones, will be investigated…
- Trial name
- GenAllertOB (NCT05768659)
- Testing
- Fear Conditioning
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Physical Fitness, Combat Readiness
Enhancement of Physical and Combat Preparedness of SAF Members
Regular and optimal fitness training has a positive effect on reducing risk or injury in addition to enhancing psychophysical and combat skills.
- Conditions
- Physical Fitness, Combat Readiness, Injury Prevention, Validation of Testing Batteries
- Trial name
- EPCPSAF-2021 (NCT05216146)
- Testing
- Strength and Conditioning
- Where
- Slovenia
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- University of Ljubljana
Peripheral Blood Stem Cell Transplantation, Hematopoietic Stem Cell Transplantation
The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation
Background: Blood cancers (such as leukemias or lymphomas) often do not respond to standard treatments. A transplant of blood stem cells from a healthy donor can help people with these cancers.
- Trial name
- NCT05436418
- Testing
- Melphalan, Sirolimus, Total Body Irradiation (TBI)
- Where
- 2 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)