Clinical trials: Conduct
Alzheimer's Disease
Disrupted Sleep, Neuroendocrine Status and the Behavioral Symptoms of AD
Over 5 million Americans have Alzheimer's disease or a related dementia, a progressive and irreversible neurodegenerative condition, affecting also close to 15 million family caregivers (CG).
- Trial name
- NCT01920672
- Testing
- Timed Planned Activity, Home Safety and Education Program
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aging
Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
The goal of this clinical trial is to compare the effects of protein consumption before sleep or immediately after exercise during 12 weeks of resistance exercise training in older adults.
- Trial name
- NCT05922475
- Testing
- Protein
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Florida State University
Breast Cancer, Sedentary Lifestyle
Developing a Healthy Lifestyle in Breast Cancer Survivors
At this time, no study has examined the effect of a lifestyle intervention with a reduced Sedentary Behavior (SB) prescription on overall physical activity, weight loss, metabolic dysfunction, and inflammation in breast cancer…
- Trial name
- NCT02677857
- Testing
- Common intervention components for Lifestyle
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Healthy Subjects, Pharmacokinetics of ASP3652
A Study to Assess the Safety, Tolerability, and Effects in and on the Body of Healthy Young and Elderly Male and Female Subjects of Ascending Multiple Oral Doses of ASP3652
The study investigates how safe ASP3652 is and how well it is tolerated when taken as multiple doses. The study also assesses how quickly and to what extent it is absorbed and eliminated from the body.
- Conditions
- Healthy Subjects, Pharmacokinetics of ASP3652, Pharmacodynamics of ASP3652
- Trial name
- NCT02243657
- Testing
- ASP3652
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Europe B.V.
Obesity
Effects of Group Vs. Home-Based Combined Exercise-Diet Program In Childhood Obesity: A Randomised Controlled Trial
The aim of this study was to compare the effect of a hospital group-based vs. home-based combined exercise-diet program for the treatment of childhood obesity.
- Trial name
- NCT01503281
- Testing
- Circuit training
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Psychology, Social, Smoking Cessation
Mindset Intervention for Nicotine Dependence
This study evaluates a new digitally delivered mindset based intervention in addition to a smartphone application (app) for smoking cessation.
- Conditions
- Psychology, Social, Smoking Cessation, Smoking (Tobacco) Addiction
- Trial name
- MIND (NCT03174730)
- Testing
- Growth Mindset, SmartQuit
- Where
- United States
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Overactive Bladder, Urge Urinary Incontinence
Safety and Applicability Study of a Novel Heat Flow Sensor Unit for Measuring Urinary Bladder Capacity
A novel sensor (a device named sensurine)was developed in the aim of real- time measurement of bladder volume. The sensurine device is a wearable, fully passive, non-invasive and compact heat flow sensor (patent pending) and…
- Conditions
- Overactive Bladder, Urge Urinary Incontinence, Enuresis, Self Clean Intermittent Catheterization
- Trial name
- NCT00437528
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Transgender, Gender Identity
Effects of Aging and Gender-Affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Men
This study will examine markers of vascular endothelial function (vascular health) and metabolic profiles in older versus younger transgender men (people who were assigned female at birth but whose gender identity is male).
- Conditions
- Transgender, Gender Identity, Vascular Stiffness, Vascular Inflammation
- Trial name
- NCT04237467
- Testing
- No intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Behavioral Dynamics, Visual Impairment
Behavioral Dynamics Between Infants With Visual Loss and Healthy Controls
An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution.
- Trial name
- NCT03431207
- Testing
- Standardized video recording for behaviors
- Where
- China
- Volunteers
- 4,196 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Compulsive Behavior
Retraining Body and Brain to Conquer Compulsions
Following the realisation that many aspects of the way we live our life, such as our diet, activity levels, and amount of screen time, can have a potent impact on mental health and brain functioning 'lifestyle' based…
- Trial name
- NCT03067636
- Testing
- Physical Exercise, Stress management training A, Stress management training B
- Where
- Australia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Monash University
Fasting, Dietary Fibre
Combining Fasting and Fibre Interventions to Optimise Their Gut Microbiome-mediated Health Benefits
This study builds on the knowledge that fasting provides metabolic health benefits and that prebiotic interventions can enhance the gut microbiome's metabolic output to likewise improve host health.
- Conditions
- Fasting, Dietary Fibre, Gut Microbiome, Metabolism Changes
- Trial name
- CoFFIe (NCT07691736)
- Testing
- Fibre Arm, Control Arm
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH
Health Knowledge, Attitudes, Practice
The Impact of a "Serious Game" on Improving Patient's Medication Knowledge
The purpose of this study is to assess the effects of an interactive educational program delivered through a patient portal on patients' medication knowledge and medication adherence.
- Trial name
- NCT01786044
- Testing
- MasterMed, Usual Care
- Where
- United States
- Volunteers
- 850 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tobacco Use Disorder, Smoking Cessation
Mechanisms of Lorcaserin for Smoking Cessation
Identifying new medication options is critical for curbing the health burdens of cigarette smoking. Currently approved smoking cessation medications act on nicotinic receptors, and additional work is needed to identify…
- Trial name
- NCT04396834
- Testing
- Lorcaserin Oral Tablet
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Telerehabilitation
Telerehabilitation in Individuals Over 65 Years of Age Having Social Isolation Due to Coronavirus (Covid-19)
In December 2019, new coronavirus pneumonia (COVID-19) erupted in Wuhan (Hubei, China) and quickly spread from a single city to the entire country in just 30 days and then attracted worldwide attention.
- Trial name
- NCT04334434
- Testing
- Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kubra Koce, MSc PT
Asthma, Reactive Airway Disease
Comparison of Asthma Programs for Schools
The purpose was to evaluate effectiveness and impact of an academic and counseling asthma health education program (SHARP) for fourth- and fifth-grade students diagnosed with asthma.
- Trial name
- CAPS (NCT01625364)
- Testing
- SHARP program, Open Airways for Schools
- Where
- United States
- Volunteers
- 432 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Tourette Syndrome, Habit Reversal Training
Extinction Learning in Adults With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still…
- Conditions
- Tourette Syndrome, Habit Reversal Training, Tic Disorders, Tics
- Trial name
- NCT04498364
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Post-traumatic Stress Disorder, Major Depressive Disorder
Adjunctive Pregnenolone in Post-Traumatic Stress Disorder (PTSD) and Depression in Operations Enduring Freedom and Iraqi Freedom (OEF/OIF) Veterans
This study will be an 8-week randomized, placebo-controlled clinical trial of pregnenolone administered adjunctively to treatment as usual in PTSD and depression in OEF/OIF Veterans.
- Trial name
- NCT00993629
- Testing
- pregnenolone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Quality of Life
Transplantoux Health Evaluation Study
The primary aim is to evaluate the short- and long-term effect of the 'Transplantoux' exercise training intervention in solid organ transplant recipients with matched control sample of transplant recipients in view of selected…
- Trial name
- THES (NCT02533245)
- Testing
- Home-based indiviualized exercise training program, Supervised group training sessions, Climb of the Mont Ventoux
- Where
- Belgium
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Depression, Anxiety
The Correlation Characteristics Between Mental Health and Gut Microbiota of College Students in Qingyuan Vocational Education City
The goal of this observational study is to learn about the mental health status and gut microbiota characteristics of college students in Qingyuan Vocational Education City.
- Trial name
- NCT06595095
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Adolescent Behavior, Parenting
Implementing a Church-based Parenting Intervention for Hispanics
The current investigation consists of the implementation and modest refinements of a culturally adapted version of the evidence-based PT intervention known as GenerationPMTO.© The adapted intervention, CAPAS-Youth, is primarily…
- Trial name
- NCT05291481
- Testing
- CAPAS-yOUTH
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
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