Clinical trials: Contraceptive Devices
Contraception, Women at Risk for Pregnancy
Evaluation of the Efficacy, Safety, and Tolerability of LevoCept
To assess the contraceptive efficacy (prevention of pregnancy) of LevoCept
- Trial name
- NCT04457076
- Testing
- LevoCept
- Where
- 27 sites in United States
- Volunteers
- 1,525 people, healthy volunteers welcome
- Sponsor
- Sebela Women's Health Inc.
HIV
Male Engagement in PMTCT Services
The study employs a quasi-experimental design in 8 public health centers in southwest Uganda offering care and treatment (C\&T) services.
- Trial name
- NCT01903889
- Testing
- clinic based intervention, clinic and community based intervention
- Where
- 7 sites in Uganda
- Volunteers
- 3,806 people, healthy volunteers welcome
- Sponsor
- FHI 360
Ovulation Inhibition
A Study to Evaluate the Effect of a Contraceptive Vaginal Ring Delivering Ulipristal Acetate Combined With a Single or Repeated Levonorgestrel on Inhibition of Ovulation, Endometrial Changes and Bleeding Patterns in Normal Cycling Women
The purpose of this study is to determine the effect of a contraceptive vaginal ring on inhibition of ovulation, endometrial changes and bleeding patterns in normal cycling women.
- Trial name
- NCT02451826
- Testing
- Ulipristal acetate
- Where
- Dominican Republic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Population Council
Healthy Volunteers
A Study of Baricitinib and Birth Control Pills in Healthy Females
The main purpose of this study is to find out how the body absorbs and breaks down a common birth control pill called Microgynon when it is given with the study drug called baricitinib.
- Trial name
- NCT01896726
- Testing
- Baricitinib, Microgynon
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Menstrual Cycle, Resistance Training
Impact of Menstrual Cycle-Based Resistance Training on Neuromuscular Performance in Female Athletes
The goal of this clinical trial is to assess the impact of menstrual cycle-based resistance training on neuromuscular function in female athletes.
- Conditions
- Menstrual Cycle, Resistance Training, Neuromuscular Function, Female Athlete
- Trial name
- MENSES (NCT06679491)
- Testing
- Resistance periodized training program (N-PF), Resistance peioridized training program (N-PL), Continuous resistance training program (C)
- Where
- Reunion
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite de La Reunion
Contraception
Oral Androgens in Man-4: (Short Title: Oral T-4)
The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration.
- Trial name
- NCT00399165
- Testing
- Testosterone Enanthate, Dutasteride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy Participants
A Study Measuring the Effectiveness of BMS-986256 Combined With Oral Contraceptive in Healthy Female Participants
A comparative study of BMS-986256 with a combined oral contraceptive in healthy female participants to determine the effectiveness when taken together
- Trial name
- NCT04016753
- Testing
- BMS-986256, Loestrin
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Polycystic Ovary Syndrome
Impact of Metformin in Teens With Polycystic Ovary Syndrome (PCOS) on Oral Contraceptive Therapy
Oral contraceptives are known to improve menstrual cycles and symptoms in PCOS, however may increase cholesterol. Metformin, a drug to improve insulin resistance, may benefit metabolic state.
- Trial name
- NCT00283816
- Testing
- Metformin, Oral Contraceptive Pill, Lifestyle Management Program
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Female Contraception
Efficacy, Safety, and Acceptability of Mifepristone 50 mg Once-weekly as a Contraceptive
Participants in the study will use mifepristone 50 mg once-a-week for one year as a contraceptive. With this, we want to confirm that the chances of getting pregnant while using this contraceptive are very small.
- Trial name
- WOMEN&More (NCT06394999)
- Testing
- Mifepristone 50 mg
- Where
- 14 sites in Netherlands
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Pharmacokinetics
Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol
The clinical phase I study aims at investigating the conversion of the contraceptive compound norethisterone within the body towards the contraceptive compound ethinylestradiol.
- Trial name
- NCT02170038
- Testing
- Microgynon, Noristerat(BAY86-6308)
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception
Efficacy and Safety of the Combined Oral Contraceptive (COC) NOMAC-E2 Compared to a COC Containing DRSP/EE (292001)(COMPLETED)(P05724)
The primary purpose of this study is to assess contraceptive efficacy, vaginal bleeding patterns (cycle control), general safety and acceptability of the nomegestrol acetate-estradiol (NOMAC-E2) combined oral contraceptive (COC)…
- Trial name
- NCT00511199
- Testing
- NOMAC-E2, DRSP-EE
- Volunteers
- 2,152 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
A Trial of Efficacy, Safety and Tolerability of LVDS (Levonorgestrel Vaginal Delivery System) During 13 Cycles
Multicentre, single arm phase III trial to assess the pearl index of LVDS. The trial lasts 13 cycles.The assessments include (but are not limited to) recording demographic data, pregnancy tests, gynaecological examinations…
- Trial name
- NCT06019533
- Testing
- LVDS
- Where
- Spain
- Volunteers
- 1,039 people, healthy volunteers welcome
- Sponsor
- Chemo Research
Pregnancy Prevention
Comparative Study of the Contraceptive Efficacy of the Cupid, Cupid 2 and FC2 Female Condom
This research study aims to assess the effectiveness of three female condoms [Cupid, Cupid 2 and Female Condom 2(FC2)] for the prevention of pregnancy among women choosing the female condom (FC) as their method of fertility…
- Trial name
- NCT04233632
- Testing
- FC2 Condom, Cupid Condom, Cupid 2 Condom
- Where
- South Africa
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Prof Mags Beksinska
Contraception, Female Contraception
Postmarketing Study of ORTHO EVRA (Norelgestromin and Ethinyl Estradiol Contraceptive Patch) in Relation to Venous Thromboembolism (Blood Clots), Stroke and Heart Attacks
The purpose of the study is to assess the occurrence of venous thromboembolism (blood clots), stroke, and heart attack in current users of ORTHO EVRA compared to current users of norgestimate-containing oral contraceptives with…
- Trial name
- NCT00331071
- Testing
- Monophasic or triphasic Oral contraceptive tablet, Ortho Evra transdermal patch containing 6 mg NGMN/0.75 mg EE
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Contraceptive Usage, Alcohol Use Complicating Childbirth
Native-Changing High-risk Alcohol Use and Increasing Contraception Effectiveness Study
Native CHOICES is a randomized controlled trial of an adapted intervention to reduce the risk of alcohol exposed pregnancies in American Indians and Alaska Natives (AI/ANs).
- Conditions
- Contraceptive Usage, Alcohol Use Complicating Childbirth, Alcohol Drinking
- Trial name
- Native-CHOICES (NCT03930342)
- Testing
- Native-CHOICES
- Where
- 2 sites in United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Washington State University
Contraceptive Usage
Contraception Decision Aid Use and Patient Outcomes
The purpose of this study is to assess the impact of a contraception decision aid mobile application on: (a) decisional conflict, (b) reproductive health self-efficacy, (c) contraceptive and reproductive health literacy, and (d)…
- Trial name
- NCT05177783
- Testing
- Tuune health questionnaire, Control health questionnaire
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Healthy
Feasibility Study Into the Contraceptive Effect of Estetrol
This is an open study in 50 young, healthy, female volunteers. Women who want to participate and who are using hormonal contraception stop using their hormonal contraceptive and wait for their first spontaneous menstruation (i.e.
- Trial name
- NCT00563472
- Testing
- estetrol, estetrol and desogestrel, estetrol and progesterone
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pantarhei Bioscience
Infections, Human Immunodeficiency Virus and Hepatitis
Study to Evaluate the Pharmacokinetics of an Oral Contraceptive Containing Levonorgestrel and Ethinyl Estradiol When Co-administered With GSK1265744 in Healthy Adult Female Subjects
This open-label, fixed-sequence crossover study aims to evaluate the effect of GSK1265744 (744) oral administration on the pharmacokinetics (PK) and pharmacodynamics (PD) of a commonly used oral contraceptive (OC) product…
- Trial name
- NCT02159131
- Testing
- Ethinyl Estadiol, Levonorgestrel, GSK1265744
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Healthy
A Study to Evaluate Hormone Patterns and Ovarian Follicular Activity With DR-1021
This is a multi-center study to evaluate hormone levels with the oral contraceptive regimen DR-1021.
- Trial name
- NCT00544882
- Testing
- DR-1021, Mircette®, Kariva®
- Where
- 4 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Bleeding, Cramping
Quick Start Insertion of Mirena and ParaGard
Intrauterine devices (IUDs) are an effective form of contraception, but only about 3.4% of women in the US report using them. Women must often wait for their menses to start, or for results of screening for sexually transmitted…
- Conditions
- Bleeding, Cramping, Pregnancy With IUD in Place, IUD Expulsion
- Trial name
- NCT01730911
- Testing
- Text message
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Columbia University