Clinical trials: Contraceptive Devices
Bone; Disorder, Development and Growth
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis
This study will determine whether the negative effects of combined oral contraceptive (COC) therapy on the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and bone turnover are dependent on the route of administration…
- Trial name
- NCT02367833
- Testing
- Combined Oral Contraceptive, Transdermal Contraceptive, Contraceptive Vaginal Ring
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Penn State University
Contraception
Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience
The primary objective of this mixed methods pilot study is to understand women's experiences with postplacental intrauterine device (IUD) insertion through postpartum semi-structured interviews.
- Trial name
- PIPPI (NCT02312726)
- Testing
- Postplacental IUD insertion
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Contraceptive Usage, Metabolic Syndrome
Metabolic Profile of Users of Hormonal and Non-hormonal Contraceptives
Evaluation of metabolic profile of users of hormonal and non-hormonal contraceptives during five years follow-up
- Conditions
- Contraceptive Usage, Metabolic Syndrome, Body Weight Changes
- Trial name
- NCT03383185
- Testing
- Intrauterine device, Combined Oral Contraceptive, Progestin-only pills
- Where
- Brazil
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Contraception
Group Versus Individual Contraceptive Counseling for Resettled African Refugee Women
To evaluate the feasibility and effectiveness of group contraceptive counseling on family planning knowledge acquisition, service satisfaction, method uptake and continuation among a group of resettled African refugee women.
- Trial name
- NCT02796586
- Testing
- Counseling
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pregnancy Prevention
A Study to Evaluate the Efficacy and Safety of DR-103 for the Prevention of Pregnancy
This is an open-label, single-treatment study. All subjects will receive 12 months of oral contraceptive therapy with DR-103. Study participants will receive physical and gynecological exams, including Pap smear.
- Trial name
- NCT00996580
- Testing
- DR-103
- Where
- 94 sites in United States
- Volunteers
- 3,597 people, healthy volunteers welcome
- Sponsor
- Teva Women's Health
Contraception
Bedsider.Org in Post-abortion Contraceptive Counseling: A Mixed Methods Study
This is a mixed methods study, incorporating a randomized controlled trial and a qualitative provider focus group, to evaluate contraceptive counseling aided by www.Bedsider.org in patients seeking first-trimester abortion.
- Trial name
- Bedsider (NCT02532946)
- Testing
- Bedsider.org counseling
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Healthy Volunteer
A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers
This randomized, double-blind, placebo-controlled, cross-over study will assess the effect of aleglitazar on the pharmacokinetics and pharmacodynamics on Microgynon® in healthy volunteers.
- Trial name
- NCT01615354
- Testing
- Aleglitazar, Microgynon®
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Cystic Fibrosis, Contraception
Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis
The long-term goal is to study the safety and effectiveness of hormonal contraception for women with cystic fibrosis (CF) and contribute to national guidelines that the Cystic Fibrosis Foundation and the Centers for Disease…
- Trial name
- CASE4CF (NCT04568980)
- Where
- 10 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraception
Study on Safety and Efficacy of an Oral Contraceptive in Long Cycles
The purpose of the study is to determine safety and efficacy of long-cycle regimens of an oral contraceptive.
- Trial name
- NCT00266032
- Testing
- Flexible (extended) treatment of EE20/DRSP (YAZ, BAY86-5300), Fixed extended treatment of EE20/DRSP (YAZ, BAY86-5300), Standard 24+4 treatment of EE20/DRSP (YAZ, BAY86-5300)
- Where
- 35 sites in Canada, Germany and 1 more
- Volunteers
- 1,166 people, healthy volunteers welcome
- Sponsor
- Bayer
Peer Counseling, LARC Desire
Influence of Peer Mentoring on Adolescent Contraceptive Decision Making
This is a prospective, randomized-controlled trial in which subjects will be randomized to receive either routine contraceptive counseling or peer mentoring plus routine contraceptive counseling.
- Trial name
- ImPACCT (NCT02157285)
- Testing
- Peer Mentor Counseling
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Healthy Females
A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects
This is a Phase 1, randomized, 2 way crossover, open-label study of the effect of multiple-dose PF 04965842 on single-dose OC PK in healthy female subjects. Subjects will be randomized to 1 of 2 treatment sequences.
- Trial name
- NCT03662516
- Testing
- PF-04965842, Ethinyl estradiol (EE) and levonorgestrel (LN)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pregnancy
Michigan Contraceptive Access, Research, and Evaluation Study: Phase 1
M-CARES will use large-scale administrative data complemented by follow-up surveys and a randomized control trial (RCT) to estimate the causal impact of greater financial access to contraception on a comprehensive set of…
- Trial name
- M-CARES (NCT03673007)
- Testing
- Gift card to be used for contraceptives that is valued at 50% of cost of name-brand IUD (August 26, 2018-March 3, 2019), Gift card to be used for contraceptives that is valued at 100% of cost of name-brand IUD (March 4, 2019-March 31, 2023)
- Where
- 9 sites in United States
- Volunteers
- 4,633 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Abortion
Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of transdermal hormonal contraception (the patch) in post-abortion subjects can improve compliance and the…
- Trial name
- NCT00235547
- Testing
- timing of initiation of transdermal patch after an abortion
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Family Planning Services, Telemedicine
Evaluation of Telemedicine Practices for Contraceptive Counseling During the COVID-19 Pandemic: A Randomized Controlled Trial
The goal of this randomized clinical trial is to evaluate the telemedicine practices for contraceptive counseling given to pregnant women during the COVID-19 pandemic.
- Conditions
- Family Planning Services, Telemedicine, Pregnant Women, Women's Health
- Trial name
- NCT05743309
- Testing
- Video call sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Contraception
Clinical Study of a Conventional and Flexible Extended Oral Contraceptive of EE/DRSP With or Without Metafolin in Latin America
The objective of this three-arm study is to evaluate the effect of a flexible extended regimen of an EE+DRSP containing OC on bleeding pattern and to investigate the compliance with daily pill intake when the investigational…
- Trial name
- NCT01331655
- Testing
- EE20/DRSP (BAY86-5300), EE20/DRSP/L-5-MTHF (BAY98-7071), EE20/DRSP/L-5-MTHF (BAY98-7071) + L-5-MTHF (BAY86-7660)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayer
Contraceptive Device; Complications
The Contraceptive Efficacy and Safety of an Intravaginal Acetic Acid Thermoreversible Gel on Chinese Women.
The study aims to explore the efficacy and safety of an intravaginal acetic acid thermoreversible gel in Chinese women of reproductive age, comparing it with nonoxinol gel by assessing the six-month Pearl Index and the incidence…
- Trial name
- contraception (NCT06203080)
- Testing
- ancetate gel, nonoxinol gel
- Where
- 4 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Research Institute for Family Planning, China
Substance Use Disorders, Reproductive Issues
Evaluating MyPath to Enhance Reproductive Autonomy and Liberate Decision-making
This is a pilot study to evaluate the acceptability and feasibility of incorporating a patient-facing reproductive decision support tool, MyPath, into existing clinical pathways in a SUD treatment program.
- Conditions
- Substance Use Disorders, Reproductive Issues, Contraception
- Trial name
- EMERALD (NCT04627805)
- Testing
- MyPath tool
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Contraception
Study to Evaluate the Contraceptive Efficacy/Safety of a Low Dose EE/LNG Transdermal Contraceptive Delivery System
The purpose of the study is to evaluate the efficacy and safety of a low dose transdermal contraceptive delivery system containing ethinyl estradiol and levonorgestrel.
- Trial name
- NCT01181479
- Testing
- AG200-15 (cycles 1-13), Lessina crossover to AG200-15
- Where
- 80 sites in United States
- Volunteers
- 1,504 people, healthy volunteers welcome
- Sponsor
- Agile Therapeutics
Pregnancy
Study of the Safety and Contraceptive Efficacy of C31G Compared to Conceptrol®
This is a multicenter, randomized, double-masked, controlled, phase III study of repeated use of C31G vaginal gel compared to Conceptrol® Vaginal Gel as the primary method of contraception over six months (183 days) and at least…
- Trial name
- NCT00274261
- Testing
- C31G, nonoxynol-9 (N-9)
- Where
- 15 sites in United States
- Volunteers
- 1,565 people, healthy volunteers welcome
- Sponsor
- Premier Research
Healthy
Evaluate the Effect of VI-0521 on the Pharmacokinetics of Oral Contraceptive in Healthy Female Subjects
This study is desgigned to look at the effect of multiple dosing administration of VI-0521 on Oral Contraceptive medication.
- Trial name
- NCT00821496
- Testing
- ethinyl estradiol, norethindrone, VI-0521
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC