Clinical trials: Contraceptive Devices
Safety
Safety, Compliance and Pharmacokinetics of Estetrol Monohydrate/Drospirenone 15/3 mg in Post-menarchal Female Adolescents
To evaluate the safety, compliance, and pharmacokinetics profile of estetrol monohydrate (E4) 15 mg combined with drospirenone (DRSP) 3 mg in post-menarchal participants between the age of 12 and 17 years + 2 months.
- Trial name
- NCT04792385
- Testing
- E4/DRSP 15/3 mg combined tablet
- Where
- 23 sites in Estonia, Finland and 4 more
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Estetra
HIV Infections
Drug Interaction - Oral Contraceptive
The purpose of this study is to administer a combined oral contraceptive containing ethinyl estradiol and norgestimate with the HIV treatment of efavirenz to healthy females in order to assess if the concentrations of the oral…
- Trial name
- NCT00399685
- Testing
- Ortho Tri-Cyclen LO, Ortho Cyclen, Ortho Cyclen + Efavirenz
- Where
- 2 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Cervical Stenosis
Use of Misoprostol in Case of Insertion Failure of Intrauterine Contraceptives
To assess the usefulnes sof misoprostol versus placebo (in a double-blind placebo controlled randomized clinical trial)to facilitate the insertion of copper-IUD and the levonorgestrel-releasing intrauterine system (LNG-IUS) in…
- Trial name
- NCT01754649
- Testing
- Misoprostol
- Where
- 2 sites in Brazil
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Luis Bahamondes
Neural Tube Defects, Contraception
Efficacy and Safety Study for an Oral Contraceptive Containing Folate
The purpose of this study is to determine whether the study drug is safe and effective
- Conditions
- Neural Tube Defects, Contraception, Oral Contraceptives (OC)
- Trial name
- NCT00468481
- Testing
- Drospirenone/Ethinylestradiol/Methyltetrahydrofolate, Drospirenone/Ethinylestradiol (Yaz)
- Where
- 9 sites in United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Bayer
Obesity
Effects of Obesity on Pharmacokinetics of the Levonorgestrel Emergency Contraceptive Pill
The purpose of this study is to determine the effects of obesity on the pharmacokinetics of the levonorgestrel (LNG) only emergency contraceptive (EC) regimen and on markers of ovulation Primary hypothesis: 1) Obese users of…
- Trial name
- NCT02104609
- Testing
- Levonorgestrel 1.5mg by mouth once
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)
This is a Phase 1, open label, fixed sequence study of the effect of multiple dose PF-06650833 on single dose OC PK in healthy female subjects.
- Trial name
- NCT05064332
- Testing
- PF-06650833, Ethinyl estradiol (EE) and levonogestrel (LN)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pregnancy, Unplanned, Contraceptive Behavior
Group-based Life Skills and Health Empowerment for Married Women to Avoid Unintended Pregnancies in India
The goal of the cluster randomized trial is to evaluate the impact of a reproductive health and empowerment intervention (TARANG) compared to the standard of care health information (control group) on the prevalence of…
- Trial name
- TARANG (NCT06024616)
- Testing
- TARANG
- Where
- India
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Contraception
Administration of Oral Contraceptives at Different Times of the Follicular Phase of the Menstrual Cycle
We hypothesize that administration of OCs at varying follicular diameters will provide an appropriate model for the study of follicular atresia in women.
- Trial name
- NCT00204438
- Testing
- 0.15mg desogestrel /0.03mg ethinyl estradiol
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Contraception
Safety and Efficacy of a Contraceptive Vaginal Ring Delivering Nestorone® and Ethinyl Estradiol
The purpose of this 1-year study is to evaluate the efficacy and safety of a new contraceptive vaginal ring (CVR) delivering low doses of Nestorone (NES), a new, nonandrogenic progestin, and ethinyl estradiol (EE), an estrogen…
- Trial name
- NCT00263341
- Testing
- NES/EE CVR
- Where
- 12 sites in United States, Australia and 6 more
- Volunteers
- 1,135 people, healthy volunteers welcome
- Sponsor
- Population Council
Adherence to Oral Contraceptive Therapy
Effect of a Smartphone Application on Oral Contraceptive Adherence in College Females
This research study is to see if smartphone applications help college women remember to take birth control better than pharmacist consultation alone. Patients will participate in this study for 6 (six) months.
- Trial name
- NCT01947842
- Testing
- Smartphone App Dosecast
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Belmont University
Contraception
Effects on Bone Mineral Density (BMD) of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG/EE (292005)(P05765)(COMPLETED)
The primary purpose of this study is to evaluate the effects of the NOMAC-E2 combined oral contraceptive (COC) on bone mineral density (BMD).
- Trial name
- NCT00511342
- Testing
- NOMAC-E2, LNG-EE
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Contraception
Adherence With Continuous-dose Oral Contraceptive: Evaluation of Self-Selection and Use
This study is designed to assess whether consumers select and use norgestrel 0.075 mg, a progestin only pill for contraception, in a manner consistent with the OTC package directions in an Over-the-Counter (OTC)-like setting.
- Trial name
- ACCESS (NCT04112095)
- Testing
- Norgestrel 0.075 mg tablets
- Where
- 38 sites in United States
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Abortion
Trial of Immediate Versus Delayed Initiation of Transdermal Hormonal Contraception After Therapeutic Abortion
This is a randomized, controlled trial investigating whether immediate versus standard, "Sunday Start", initiation of transdermal hormonal contraception (the patch) in post-abortion subjects can improve compliance and the…
- Trial name
- NCT00235547
- Testing
- timing of initiation of transdermal patch after an abortion
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
IUD
Trans Caesarean Intra Uterine Contraceptive Device Insertion Versus Conventional Postpartum 6 Weeks Insertion
To compare immediate post-placental intrauterine contraceptive device insertion versus conventional placement at 6 weeks interval (often referred to as delayed or interval insertion) as regard to:- 1. Patient satisfaction. 2.
- Trial name
- IUDinsertion (NCT06023849)
- Testing
- IUD insertion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Healthy Volunteers
A Study to Evaluate Effects of CC-99677 on the Pharmacokinetics of an Oral Contraceptive in Healthy Female Participants
The purpose of this study is to evaluate the effect of CC-99677 coadministration on the pharmacokinetics (PK) of an oral contraceptive (OC).
- Trial name
- NCT04718636
- Testing
- Oral Contraceptive (Ortho Tri-Cyclen or its generic equivalent), CC-99677
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Celgene
Adolescent Pregnancy
Adolescent Postpartum Contraceptive Counseling Intervention
Postpartum contraceptive counseling varies widely in its provision; no standardized practice has been well-established by the literature.
- Trial name
- PPCI (NCT01814930)
- Testing
- Brief standardized contraceptive counseling intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Contraception
Pharmacokinetic and Pharmacodynamic Study of Cyclofem
Cyclofem® is a monthly injectable contraceptive containing 25 mg of medroxyprogesterone acetate (MPA) and 5 mg of estradiol cypionate (E2C), a long-acting ester of estradiol.
- Trial name
- NCT01699022
- Testing
- Injection Cyclofem
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries Limited
Contraception, Liver Metabolism
"E4/DRSP Endocrine Function, Metabolic Control and Hemostasis Study"
The proposed study will provide an assessment of the effect of this combination on endocrine function, metabolic control and hemostasis during 6 treatment cycles. This will be compared to the effects of two reference COCs.
- Conditions
- Contraception, Liver Metabolism, Hemostasis Parameter
- Trial name
- NCT02957630
- Testing
- 15 mg E4/3 mg DRSP, 30 mcg EE/150 mcg LNG, 20 mcg EE/3 mg DRSP
- Where
- Netherlands
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Estetra
Sexual Abstinence, HIV
Affecting the Epidemiology of HIV in Uganda
The investigators propose to develop a comprehensive, text messaging-based HIV prevention program for Ugandan adolescents 18-22 years of age.
- Conditions
- Sexual Abstinence, HIV, Contraceptive Usage
- Trial name
- NCT02729337
- Testing
- ITG (In This Together)
- Where
- Uganda
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research
Pharmacokinetics of Isavuconazole, Pharmacokinetics of Ethinyl Estradiol and Norethindrone
Drug Interaction Study of Isavuconazole and Oral Contraceptive Containing Ethinyl Estradiol and Norethindrone
The purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics (PK) of a single dose of contraceptive in healthy post-menopausal women.
- Conditions
- Pharmacokinetics of Isavuconazole, Pharmacokinetics of Ethinyl Estradiol and Norethindrone, Healthy Volunteers
- Trial name
- NCT01597986
- Testing
- isavuconazole, Oral Contraceptive (ethinyl estradiol / norethindrone)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.