Clinical trials: Contraction
Pupil Diameter, Pupil Contraction Rate
The Guiding Significance of Pupil Monitoring in the Perioperative Period
The pupil diameter is affected by both sympathetic and parasympathetic nerves, and its latency and response amplitude mainly reflect the functional status of the parasympathetic nerve.
- Conditions
- Pupil Diameter, Pupil Contraction Rate, Pupil Light Reflection
- Trial name
- NCT04820374
- Testing
- pupil's light and pupil diameter
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yangzhou University
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ventricular Tachycardia, Premature Ventricular Contraction
DOACs for Stroke Prevention Post Ventricular Tachycardia Ablation
The purpose of this study is to learn if taking a drug called direct oral anticoagulant after an ablation procedure keeps blood clots from forming and lowers the chance of having a stroke in patients with ventricular tachycardia…
- Conditions
- Ventricular Tachycardia, Premature Ventricular Contraction, Stroke
- Trial name
- STROKE-VT (NCT02666742)
- Testing
- DOAC, Aspirin
- Where
- 5 sites in United States, India
- Volunteers
- 246 people
- Sponsor
- Kansas City Heart Rhythm Institute
Premature Ventricular Contraction
LLTS to Treat Premature Ventricular Contractions
This randomized control trial is designed to explore the effect of low-level tragus stimulation in patients with frequent premature ventricular contractions.
- Trial name
- TREAT-PVC (NCT04909528)
- Testing
- Low-level tragus stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cerebral Palsy, Muscle Contraction
The Muscle in Children With Cerebral Palsy - Longitudinal Exploration of Microscopic Muscle Structure.
Cerebral palsy (CP) is a motor impairment due to a brain malformation or a brain lesion before the age of two. Spasticity, hypertonus in flexor muscles, dyscoordination and an impaired sensorimotor control are cardinal symptoms.
- Conditions
- Cerebral Palsy, Muscle Contraction, Muscle Spasticity
- Trial name
- CPBiopsyBTX (NCT05497609)
- Testing
- no intervention. Care as ususal
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Eva Ponten
Braxton Hicks' Contractions
IMPACTS OF BRAXTON-HICKS CONTRACTIONS ON COMPUTERISED CARDIOTOCOGRAPHY PARAMETERS: A POTENTIAL LINK.
Several types of research examined the relationship of Braxton-Hicks contractions and uterine flow. Nevertheless, no one considered the relationship of the maternal perception of Braxton-Hicks contractions with the fetal…
- Trial name
- NCT04417296
- Testing
- antepartum computerised cardiotocography analysis
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- University of Campania Luigi Vanvitelli
Premature Ventricular Contractions
Use of MIBG Scan Images in PVC Ablations
The purpose of this study is to assess if Single Photon Emission Computed Tomography (SPECT) demonstrating cardiac innervation can be integrated into current electrophysiology voltage mapping system and provide improved guidance…
- Trial name
- PVC-MIBG (NCT02279030)
- Testing
- MIBG nuclear scan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Labor Pain, Contraction
Fetal Life: Smart-Device Based Uterine Activity Monitoring
This study will compare the performance of a contraction monitor (tocometer) device developed by Fetal Life with standard tocometer devices.
- Trial name
- NCT03940365
- Testing
- Fetal Life tocometer device
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Fetal Life LLC
Indication for Peripheral Intravenous Catheterization, Atrial Flutter
SHERLOCK 3CG™ Diamond Tip Confirmation System
This study is a single-arm, prospective, multi-center study to assess clinical performance of the SHERLOCK 3CG™ Diamond Tip Confirmation System (TCS) with MODUS II software for confirming correct tip position of peripherally…
- Conditions
- Indication for Peripheral Intravenous Catheterization, Atrial Flutter, Premature Atrial Contraction, Premature Ventricular Contraction
- Trial name
- MODUS II (NCT03288766)
- Testing
- PICC placement with SHERLOCK 3CG™ Diamond TCS with MODUS II software
- Where
- 8 sites in United States, Australia
- Volunteers
- 232 people
- Sponsor
- C. R. Bard
Urinary Incontinence,Stress, Ultrasound
Ultrasound and Pelvic Floor Muscle Training
The objective is to validate the use of ultrasound measurements (urethral mobility, movement of the ano-rectal angle, elastography measurements) in women with urinary incontiennce before and after pelvic floor muscle training…
- Conditions
- Urinary Incontinence,Stress, Ultrasound, Elastography, Contraction; Pelvic
- Trial name
- ERP (NCT04361890)
- Testing
- perineal ultrasound
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Caen
Premature Ventricular Contraction
Efficacy and Safety of Metoprolol Tartrate Tablets Combined With Chinese Traditional Medicine on Premature Ventricular Complex.
Objective: investigators investigated the effects of metoprolol tartrate plus Tongmai Yangxin Pill on premature ventricular complexes and cardiac function in patients with premature ventricular complex.
- Trial name
- NCT05008250
- Testing
- Tongmai Yangxin Pill (TMYXP), metoprolol tartrate
- Volunteers
- 584 people
- Sponsor
- Xuanwu Hospital, Beijing
Hypertrophy, Contraction
Resistance Training Effects on Muscle Morphological, Mechanical and Contractile Properties
The aim of the research project is to investigate the influence of resistance-training prescription (repetition duration, time under tension and training volume) and sex have on morpho-functional adaptations of upper and…
- Trial name
- NCT04845295
- Testing
- resistance training
- Where
- Serbia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies
Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)
Premature ventricular contractions (PVCs) coexist in patients with heart failure (HF) and LV dysfunction. Frequent PVCs have shown to induce a reversible cardiomyopathy (PVC-CM).
- Trial name
- PAPS (NCT03228823)
- Testing
- Radiofrequency ablation, Amiodarone (Antiarrhythmic drug)
- Where
- 11 sites in United States, Canada
- Volunteers
- 5 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Premature Ventricular Contractions, Congestive Heart Failure
Early Elimination of Premature Ventricular Contractions in Heart Failure
Premature ventricular contractions (PVC) are a very common irregular heart beat (arrhythmias) even in patients without heart disease. Frequent PVCs are thought to occur in about 1-4% of the general population.
- Trial name
- EVAC-HF (NCT01757067)
- Testing
- PVC ablation
- Where
- 8 sites in United States, Canada
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Premature Ventricular Contraction, Ventricular Tachycardia
Ventricular Arrhythmia Ablation With the Use of Non-Invasive ECG Imaging Technology
Researchers are trying to determine if the use of software called VIVO, made by Catheter Precision, Inc. can shorten the length of time it takes to perform an ablation procedure for either premature ventricular contractions…
- Trial name
- NCT04219501
- Testing
- VIVO
- Where
- United States
- Sponsor
- Mayo Clinic
Muscle Atrophy or Weakness, Muscle Contraction
Core Exercises Effects on Muscle Imbalances
This study aims in investigating the effects of a core muscles' strengthening program on core muscles' atrophy and contraction ability.
- Conditions
- Muscle Atrophy or Weakness, Muscle Contraction, Core Stability
- Trial name
- NCT04450615
- Testing
- Core stability
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Athanasios Ellinoudis
Premature Ventricular Contraction
Remote Magnetic Versus Manual Navigation-guided Ablation for Non-outflow Tract Premature Ventricular Contractions: a Prospective, Randomized, Controlled Trial
This prospective, randomized, controlled trial is designed to compare the safety and efficacy of remote magnetic navigation-guided ablation for ventricular premature complexes arising from non-outflow tracts with manual control…
- Trial name
- NCT04519112
- Testing
- Catheter Ablation
- Volunteers
- 200 people
- Sponsor
- Ruijin Hospital
Uterine Contraction, Pregnancy
Comparative Study of the Propagation of Uterine Electrical Activity (EHG) in Pregnant Women During Pregnancy and During Labour
The original aspect of the methodology proposed for this study concerns the use of as many as 16 electrodes to study the propagation and coordination (or synchronization) of uterine contraction.
- Conditions
- Uterine Contraction, Pregnancy, Delivery, Obstetric
- Trial name
- PropEHG (NCT02814344)
- Testing
- Electrohysterography
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pelvic Floor, Muscle
Intravaginal Electrical Nerve Stimulation in Women With Non-contracting Pelvic Floor
It is estimated that about 30% of women cannot voluntarily contract the pelvic floor muscles (PFM). PFM training (PFMT) represents the first therapeutic option for the treatment of female urinary incontinence (UI), however the…
- Conditions
- Pelvic Floor, Muscle, Contraction, Electric Stimulation Therapy
- Trial name
- NCT03319095
- Testing
- Intravaginal Electrical Nerve Stimulation
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Premature Ventricular Contraction
Urine Levels of Metanephrin and Normetanephrin in Patients With Frequent Ventricular Premature Complex
Enhanced automaticity process is the underlying mechanism for arrhythmias due to excess catecholamines. Catecholamines may increase in patients with PVC. Metabolites of catecholamines are metanephrine and normetanephrine.
- Trial name
- NCT03447002
- Testing
- 24 hours urine levels metanephrine and normetanephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- TC Erciyes University