Clinical trials: Contractions
Hypotension
Effects of Ephedrine, Phenylephrine, Norepinephrine and Vasopressin on Contractility of Human Myometrium and Umbilical Vessels: An In-vitro Study
Hypotension is one of the most common adverse effects of spinal anesthesia for cesarean deliveries, affecting as many as 55-90% of mothers.
- Trial name
- NCT04053478
- Testing
- Ephedrine, Phenylephrine, Norepinephrine
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Ventricular Premature Complexes
CBT for Premature Ventricular Contractions
The purpose of the present interdisciplinary research program is to develop and evaluate a disease-specific cognitive behavior therapy (CBT) protocol to increase quality of life (QoL) and reduce symptom burden in patients with…
- Trial name
- PVC-CBT (NCT05087238)
- Testing
- CBT
- Where
- Sweden
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pregnancy
Effects of Light on Melatonin and Contractions in Pregnant Women
Specific Aim: Test the hypothesis that ocular light exposure will suppress melatonin secretion and reduce uterine contractions in women at late term pregnancies. Secondary aim.
- Trial name
- NCT01863446
- Testing
- Lighting1, Lighting2
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Premature Atrial Contractions, Premature Ventricular Contractions
Coffee and Real-time Atrial and Ventricular Ectopy
Atrial fibrillation (AF) and heart failure (HF) are morbid, costly, and incompletely understood diseases that have reached epidemic proportions worldwide.
- Trial name
- CRAVE (NCT03671759)
- Testing
- Start: On Caffeine, Start: Off Caffeine
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ageing, Muscle Fatigue Caused by Repetitive Muscle Exercise
The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction
The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes.
- Trial name
- NCT07090603
- Testing
- Knee extension exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Pelvic Floor, Abdominal Muscles
Effectiveness of Abdomino-pelvic Muscle Contraction Education Programme in Healthy Male University Students
This research study investigates the effectiveness of an educational intervention aimed at improving awareness and control of pelvic floor (PF) and abdominal muscle contractions in healthy young male university students.
- Conditions
- Pelvic Floor, Abdominal Muscles, Abdominal Muscles/ultrasonography
- Trial name
- NCT06786182
- Testing
- PFM Educational Program
- Where
- Spain
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Exercise-induced Muscle Damage
Effects of Inter-Set Rest Intervals on Muscle Damage After Flywheel Exercise in Untrained Men (RCT)
This randomized parallel-group clinical trial will compare the acute effects of three different inter-set rest intervals during a single lower-limb flywheel resistance exercise session in untrained men.
- Trial name
- NCT07679971
- Testing
- Flywheel resistance exercise with 1-minute inter-set rest, Flywheel resistance exercise with 2-minute inter-set rest, Flywheel resistance exercise with 3-minute inter-set rest
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Vicosa
Gallbladder; Functional Disturbance
A Novel Strategy for Evaluating Gallbladder Contraction Function by Ultrasound
This study is a prospective, single-center, single-blind, cross-over trial conducted at a tertiary hospital, aiming to determine the evaluation of oral functional fatty acids on gallbladder contractile function.
- Trial name
- NCT07039864
- Testing
- protein bar first, fried eggs first
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Myofascial Pain Syndrome (MPS)
Immediate Effects of Shock Wave Therapy With Stretching or Isometric Contraction on Upper Trapezius
Excessive use of smart devices and prolonged sitting posture in modern daily life can lead to potential hypertonicity and functional impairment of the upper trapezius even in healthy individuals.
- Trial name
- rESWT (NCT07609173)
- Testing
- Radial Extracorporeal Shock Wave Therapy and Stretching, Radial Extracorporeal Shock Wave Therapy and Isometric Contraction
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sahmyook University
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Premature Ventricular Beats, Premature Ventricular Complexes
Flecainide in Idiopathic Premature Ventricular Contractions and Related Cardiomyopathy
The UNIFLECA study is a prospective, single-arm, observational cohort evaluating the efficacy, safety, and tolerability of flecainide (in the form of Sanocard) in adults with frequent idiopathic premature ventricular contractions…
- Conditions
- Premature Ventricular Beats, Premature Ventricular Complexes, Premature Ventricular Contraction (PVC), Arrhythmia Ventricular
- Trial name
- UNIFLECA (NCT06949748)
- Testing
- Flecainide (monotherapy)
- Where
- 6 sites in Greece
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Athens
Pelvic Floor Muscle Weakness
Pelvic Floor Muscle Contraction Among Physiotherapy Students Before and After "Women Health" Course
The study aim is to evaluate the ability to correctly contract pelvic floor muscle among physiotherapy students before and after "women health" course.
- Trial name
- NCT03917615
- Testing
- pelvic floor contraction
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Postpartum Hemorrhage
The Relaxant Effect of Nitroglycerin on Oxytocin Desensitized Human Myometrium
Oxytocin causes myometrial contraction via the oxytocin receptor (OTR). Desensitization of the OTR after exposure to oxytocin has been demonstrated in previous studies.
- Trial name
- NCT03408054
- Testing
- Oxytocin, Nitroglycerin
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Subluxation of Joint of Lumbar Spine
The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment
This study investigated the effects of spinal manipulation on central nervous system activity. The presence of postactivation potentiation, an increase in muscular force production following prior muscular contractions, was…
- Trial name
- NCT02848456
- Testing
- Spinal Manipulation, Max Voluntary Isometric Contraction, SM+MVIC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Grant Sanders
Healthy
The Effect of Thermotherapy on Recovery and Performance
This study investigates the effects of cooling on the recovery and performance characteristic in young healthy subjects. The study is divided in two projects: Project A: investigates the effects of 20 min.
- Trial name
- Cryotherapy (NCT02506283)
- Testing
- Zamar Therapy CT clinic
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Healthy Subjects, Elective Surgical Procedure
"Electromagnetical Stimulation of Phrenic Nerve to Generate Contraction of the Diaphragm"
The scientific study is intended to show that external non-invasive electromagnetic stimulation can be used to safely and effectively stimulate the phrenic nerve in awake healthy subjects as well as in ventilated, anesthetized…
- Trial name
- NCT04884698
- Testing
- Stimit Activator
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stimit AG
Healthy
Reference Values for the One Repetition Maximum Test of Knee Extensors for Brazilians.
Muscle strength is important for health and can affect how well people live, even increasing the risk of death in adults and older people.
- Trial name
- NCT06648421
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Pregnancy; Habitual Aborter, Weeks of Gestation 37 or More
Accuracy and Reliability of Fetal Heart Rate and Uterine Contraction Monitoring Method
Clinical Investigation Protocol for a study designed to determine the equivalence of the Monica AN24 monitor to Philips 50XM for fetal heart rate (FHR) and uterine contraction (UC) monitoring during labor.
- Trial name
- NCT01280357
- Testing
- Monica AN24 (K101081), Philips 50XM
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Monica Healthcare Ltd
Healthy
Effect of the Motilin Receptor Agonist, Erythromycin, on Hunger and Food Intake; Study of Role of Cholinergic Pathways
In this study, the investigators will evaluate if the food intake associated with the infusion of erythromycin is caused by the phase 3 contractions or by another yet unknown effect of erythromycin.
- Trial name
- NCT02633579
- Testing
- erythromycin lactobionate, Atropine, Erythromycin with atropine
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Chronic Ankle Instability
Muscle Strength Assessment in Patients With Chronic Ankle Instability
Patients with chronic ankle instability (CAI) show biomechanical and neuromuscular alterations during the performance of functional movements not only at the ankle joint level, but also in more proximal joints and segments.
- Trial name
- KNEE-CAI (NCT05273177)
- Testing
- Chronic ankle instability
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli