Clinical trials: Contrast Agent
Refractive Error, Cataract
Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions
Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for…
- Conditions
- Refractive Error, Cataract, Maculopathy
- Trial name
- NCT02028351
- Where
- 2 sites in United States, Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinclair Technologies, LLC
Peripheral Neuropathy
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer
Purpose: The purpose of the study is to test a new way of measuring nerve damage in women with breast cancer receiving chemotherapy drug paclitaxel (Taxol).
- Trial name
- NCT02549534
- Testing
- Axon Reflexes, Axon Flares, Self-Reported Signs & Symptoms of CIPN
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Total Occlusion of Coronary Artery
REduction of Contrast Via DyeVert Used in CTO Procedures
The is an observational, prospective study to evaluate the effect of the DyeVert System on contrast volume administration in patients undergoing clinically-indicated chronic total occlusion (CTO) percutaneous coronary…
- Trial name
- REDUCe (NCT03118544)
- Testing
- DyeVert System
- Where
- 3 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Breast Cancer
Contrast Ultrasound Detection of Sentinel Lymph Nodes
This is a two part, open label, non-randomized trial of women with a breast cancer diagnosis scheduled for excisional surgery and sentinel lymph node (SLN) evaluation.
- Trial name
- NCT02652923
- Testing
- Sonazoid; Perflubutane for Injection
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Cardiac Disease, Covid19
Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT
The main aim is to validate non-gated 5-min computed tomography myocardial relative enhancement (CT-MRE), which can be readily estimated via contrast-enhanced non-gated chest CT, as a tool for estimating myocardial extracellular…
- Conditions
- Cardiac Disease, Covid19, Cardiotoxicity, Extracellular Space Alteration
- Trial name
- NCT04880317
- Testing
- Cardiac Magnetic Resonance, Additional CT acquisition, Blood tests
- Where
- Italy
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Contrast Induced AKI
Protective Effects of Oral L-Arginine CI-AKI
This trial was performed to examine the efficacy of oral L-arginine for preventing CI-AKI in chronic kidney disease (CKD) patients.
- Trial name
- NCT02455960
- Testing
- L-arginine
- Where
- Thailand
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Contrast-induced Nephropathy
Efficacy Study of Vitamin D to Treat Contrast-induced Nephropathy
The investigators planned to research the effect of vitamin D supplementation on the incidence of contrast-induced nephropathy in patients undergoing coronary angiography.
- Trial name
- NCT02489240
- Testing
- vitamin D3 tablets
- Where
- China
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease, Coronary Artery Stenosis Stent
Deep Learning CAD Screening on Chest CT
Coronary artery disease (CAD) is one of the leading causes of death worldwide. Many people have early atherosclerosis without symptoms, and some may develop significant coronary stenosis before any warning signs appear.
- Trial name
- CAD-AI (NCT07181512)
- Testing
- Deep Learning Analysis of Non-contrast Chest CT
- Where
- 2 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yifan Guo
Human Immunodeficiency Virus (HIV), Cardiovascular Disease (CVD)
The Effects of Statin Therapy on Coronary Flow Reserve and Inflammatory Markers in HIV-Positive Patients
The purpose of this study is to determine whether the use of rosuvastatin in Human Immunodeficiency Virus (HIV) infected individuals lowers inflammation in blood vessels, improves blood circulation in the small arteries that…
- Trial name
- NCT02234492
- Testing
- Rosuvastatin
- Where
- 2 sites in Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Aging Problems
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or…
- Trial name
- VAMP-Aging (NCT07563725)
- Testing
- Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS)
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Myocardial Ischemia
Ischemic Memory Imaging With Myocardial Contrast Echocardiography
The overall aim of this study is to determine whether non-invasive imaging with myocardial contrast echocardiography using can provide information on the presence and spatial extent of recent myocardial ischemia by non-invasive…
- Trial name
- NCT03009266
- Testing
- Sonazoid
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Raynaud Disease, Scleroderma, Systemic
Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
The aim of the study is to determine if postocclusive hyperemia of palmar and dorsal face of the hand with Laser speckle contrast imaging discriminate between patients with systemic sclerosis, subjects with primary Raynaud's…
- Trial name
- SPECIES (NCT01743612)
- Testing
- laser speckle contrast imaging, Cooling
- Where
- 2 sites in France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
AKI, Contrast-induced Nephropathy
Establishing Clinical Utility of a New Diagnostic Test in Patients Undergoing Cardiac Catheterization
This study will collect high-quality randomized controlled data across the U.S. from practicing cardiologists performing invasive/interventional procedures and determine how they currently manage patients at risk for CIN and how…
- Trial name
- NCT04266834
- Testing
- Experimental Arm
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Glaucoma
Spaeth/Richman Contrast Sensitivity Test
The Spaeth-Richman Contrast Sensitivity (SPARCS) test is a new method of assessing contrast sensitivity. The test, another way to measure vision, is performed on any standard computer with internet access.
- Trial name
- SPARCS (NCT01300949)
- Testing
- Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Oocyte Competence
Modulation Contrast Microscopy Imaging for Oocyte Quality Assessment
The present study aims to describe novel non-invasive parameters related to the competence of female reproductive cells (oocytes).
- Trial name
- NCT03683290
- Testing
- Image acquisition and analysis
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center for Reproductive an Genetic Health
Breast Cancer
Cone Beam Computed Tomography for Breast Imaging
The primary aim of this study is to investigate the use of cone beam computed tomography (CBCT) for breast imaging in the diagnostic setting by providing a compelling body of evidence incorporating both non-contrast and contrast…
- Trial name
- CBCTBI (NCT00972413)
- Testing
- Computed Tomography
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Koning Corporation
Chronic Kidney Diseases, Cystic Kidney Disease
Contrast-enhanced Ultrasound for Complex Kidney Lesion Diagnosis in Patients With CKD Extension
The purpose of this research study is to evaluate contrast-enhanced ultrasound for kidney malignancies.
- Trial name
- CEUS-CKDx (NCT03196076)
- Testing
- Perflutren Lipid microsphere
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Sports Physical Therapy
Concurrent Training on the Performance of Team Sports Athletes
This study will add to the existing pool of knowledge with more appropriate sample size. The main purpose will be to provide coaches with a practical proposal for concurrent training(CT) to improve athletes' performance in mixed…
- Trial name
- NCT05002712
- Testing
- Heavy resistance training, Contrast strength training, Elastic resistance training
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University