Clinical trials: Controlled Oxygen Therapy
Anxiety
The Effect of Emotional Freedom Technique and Virtual Reality Glasses on Anxiety and Vital Signs
The aim of the study was to examine the effects of the emotional freedom technique and virtual reality glasses applied to individuals receiving hyperbaric oxygen therapy for the first time on anxiety and vital signs.
- Trial name
- NCT06384274
- Testing
- Emotional Freedom Technique, Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Hypoxia, Desaturation of Blood
SpO2 Accuracy Validation of the OxySoft Sensor Via Reference CO-Oximetry Motion Study
SpO2 (oxygen saturation) and pulse rate accuracy of pulse oximetry equipment, OxySoft Sensor/N-600x and OxySoft Sensor/N-395, continuous measure of arterial oxygen saturation during hypoxic state throughout motion and non-motion…
- Trial name
- NCT04559763
- Testing
- Non-Invasive Controlled Hypoxia, Introduction of Motion conditions: tapping or rubbing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Dental Anxiety, Impacted Third Molar Tooth
Anxiety Control by Erythrina Mulungu
This study evaluated the effectiveness of the Erythrina mulungu in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT01948622
- Testing
- Mulungu
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liane Maciel de Almeida Souza
Hand Injuries/Disease Requiring Surgery to the Hand
A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Hand surgery requires a reduced blood flow to the hand during the operation, which is achieved using a tourniquet (tightly inflated circumferential cuff) around the upper arm. However this tourniquet is painful.
- Trial name
- ReTAP (NCT01611064)
- Testing
- Oxygen, Medical air
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Testing Accuracy, Device Performance
Controlled Oxygen Desaturation Study of the Neonatal Wireless Transmission System
This study aims to test the oxygen saturation component of the newly developed NeWTS monitoring system and compare readings from NeWTS to a traditional wired clinical monitor.
- Trial name
- NeWTS-DS (NCT07813091)
- Testing
- Neonatal Wireless Transmission System
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kathryn Beardsall
Long COVID, Post-COVID-19 Condition
Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen.
- Trial name
- MitoLoCo (NCT07134673)
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Oxidative Stress, Fetal Distress
Maternal Oxygen Use During Delivery and Cord Blood Superoxide Dismutase
When exposed to oxygen immediately after birth, newborns suffer from an oxidative stress with a significant decrease in serum concentration of the anti-oxidant enzyme superoxide dismutase.
- Trial name
- NCT01042262
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Washington University
Adult Subject
Effect of Super-Oxygenated Water on Blood Oxygen Saturation
Therapeutic delivery of additional Oxygen to blood stream via hyperbaric and extracorporeal oxygenation that raises blood Oxygen saturation level, apart from oxygenation in the lungs, is known to induce tissue repair, restore…
- Trial name
- NCT07016191
- Testing
- Ingestion of Water
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inhale, Inc
Extraterrestrial Habitation Systems, Lunar Surface Habitation
A Multiphase Operational and Environmental Assessment of Lunar Surface Habitation, Lunar Gateway Transit Systems, and Acceleration Pathways for Sustained Human Habitation of the Martian Surface
This study evaluates the operational, environmental, and habitation-system requirements for sustained human presence on the lunar surface, the performance of the Lunar Gateway as a transit and staging architecture, and the…
- Conditions
- Extraterrestrial Habitation Systems, Lunar Surface Habitation, Lunar Water-Ice Resource Assessment, In-Situ Resource Utilization (ISRU)
- Trial name
- LUMEN-HAB (NCT07546461)
- Testing
- Habitat Systems Evaluation, Water-Ice Resource Utilization Assessment, EVA and Mobility Operations
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Patients Scheduled for Any Oral Surgical Flap Procedure That Require Suturing Will be Included in This Study
Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization
To assess the antibacterial efficiency of oxygenated gel therapy on wound healing and microbiological colonization around surgical sutures
- Trial name
- NCT06705920
- Testing
- topical oxygen gel
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Barotrauma;Ear, Tympanum; Perforation
Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions
Middle ear barotrauma represents the predominant complication associated with hyperbaric oxygen therapy, manifesting symptoms ranging from otalgia to tympanic membrane perforation.
- Trial name
- NCT06408363
- Testing
- Maneuver group
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Felicio Rocho
Deep Sedation, High Flow Nasal Canula
HFNO Flow Rates and Cerebral Oxygenation During Deep Sedation for Cystoscopy
For Patients and Families This study aims to investigate how high-flow oxygen therapy affects oxygen levels, especially brain oxygenation, during cystoscopy procedures performed under sedation.
- Conditions
- Deep Sedation, High Flow Nasal Canula, Cerebral Oxygenation, PSI
- Trial name
- NCT07630038
- Testing
- High-Flow Nasal Oxygen 40 L/min (HF40), High-Flow Nasal Oxygen 55 L/min (HF55), High-Flow Nasal Oxygen 70 L/min (HF70)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Firat University
Tachycardia, Hypertension
To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.
The goal of this clinical trial is to to observe the haemodynamic parameters including Heart Rate Blood pressure Respiratory rate and Oxygen Saturation with or without giving reversal agent on extubation in patients receiving…
- Conditions
- Tachycardia, Hypertension, Hypoxia, Hyperventilation
- Trial name
- NCT07097441
- Testing
- neostigmine (reversal agent)
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Heart Rate Control, Athlete
HRV-based Training Effects in Athletes
Monitoring individual responses to training is an important key factor to prescribe to most effective training programs. Heart-rate variability (HRV) could be used for monitoring the training status of endurance athletes in order…
- Conditions
- Heart Rate Control, Athlete, Emotions
- Trial name
- HRV-btA (NCT04150952)
- Testing
- HRV-based training, TRAD training
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Oxygen, pH
Comparison of the Effects of High-flow Nasal Cannula Oxygen and Jet Ventilation Techniques
Endoscopic microsurgical procedures of the larynx (direct examination-bx, microlaryngeal resection) require the anesthesiologist and surgeon to work in the same area throughout the procedure, and while ventilation is provided…
- Conditions
- Oxygen, pH, End-tidal Carbon Dioxide
- Trial name
- NCT05746949
- Testing
- oxygenization techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Mitochondrial Oxygenation Measurement, Surgical Site Infection
Anaesthetic Management Guided by COMET Measurements
Surgical site infection (SSI) is a significant cause of morbidity and mortality, prolonged hospital stays and healthcare costs. Perioperative low tissue oxygen tension is associated with a high risk of SSI.
- Trial name
- AIMED COMET (NCT05841576)
- Testing
- COMET monitoring device
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rick Hulskes
Pulse Oximetry
PULSE OXIMETRY Performance Test for a Software Medical Device 'Vitacam'
This clinical investigation aims to collect data for algorithm development and testing of Vitacam as well as to later validate the system using a simultaneously collected, but segregated, hold-out validation dataset.
- Trial name
- NCT06912516
- Testing
- Controlled desaturation
- Where
- Finland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Evondos Oy
Diabetic Kidney Disease, Type 1 Diabetes
Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance
Type 1 diabetes (T1D) is a complex metabolic disorder with many pathophysiological disturbances including insulin resistance (IR) and mitochondrial dysfunction which are causally related to the development of diabetic kidney…
- Conditions
- Diabetic Kidney Disease, Type 1 Diabetes, Diabetes, Diabetes Mellitus
- Trial name
- CROCODILE (NCT04074668)
- Testing
- Aminohippurate Sodium Inj 20%, Iohexol Inj 300 milligrams/milliliter (mg/ml), PET/CT Scan
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Oxygen Toxicity, Oxidative Stress
Effect of Hydrogen Gas on Hyperbaric Oxygen Toxicity
The goal of this trial is to investigate whether adding a small fraction of hydrogen gas to an oxygen-enriched breathing mixture can reduce pulmonary oxygen toxicity (POT) in healthy and active divers from the Swedish Armed…
- Conditions
- Oxygen Toxicity, Oxidative Stress, Hyperoxia, Hyperbaric Oxygen
- Trial name
- NCT07263399
- Testing
- Inhaled Hydrogen-Enriched Oxygen Gas, Inhaled Nitrogen-Enriched Oxygen Gas
- Where
- 2 sites in Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Blekinge Institute of Technology
Kangaroo Mother Care Method
Impact of Intermittent Kangaroo Mother Care Versus Conventional Care Method on Vital Sign and Arterial Oxygen Saturation in Preterm Hospitalized in Neonatal Intensive Care Unit
To study the vital sign ,oxygen arterial saturation of preterm babies provided skin to skin contact versus conventional care from birth to discharge
- Trial name
- NCT05491265
- Testing
- Intermittent Kangaroo mother care
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University