Clinical trials: Corneal Topography
Corneal Topography
Study of Clinical Performance of Corneal Topography Measurement Using an Optical Biometer
The purpose of this study is to quantify in-vivo repeatability of a new corneal topography measurement mode of an optical biometer, and the clinical performance of measurement in comparison to reference devices.
- Trial name
- NCT01861925
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Haag-Streit AG
Myopia, Astigmatism
Compare Anterior Chamber Biometry in Healthy and Post-LASIK Patients
In this study, the investigators employed Visante-OCT (Carl Zeiss, USA), an anterior chamber optical coherence tomography, to monitor the change of anterior chamber dimensions.
- Trial name
- NCT00838734
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Refractive Surgery
CONTOURA vs WFO Ablation PRK & LASIK
This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs.
- Trial name
- NCT05037370
- Testing
- Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
Cataract, Keratoconus
Clinical Study - ES 900 - 2020-2
The EYESTAR 900 with software version i9.5.1.0 includes new analysis functionality. Since its clinical performance cannot be assessed based solely on clinical literature as found in the Clinical Evaluation Report, further data…
- Trial name
- NCT04392349
- Testing
- Haag-Streit EYESTAR 900, Tomey CASIA 2, Oculus PENTACAM HR
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Haag-Streit AG
Keratoconus, Eye Diseases
Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images
Monocentric clinical study to develop an imaging analysis algorithm for the Eyestar 900 to identify keratoconus corneas and improve biometry for intraocular lens calculations
- Conditions
- Keratoconus, Eye Diseases, Cataract, Corneal Ectasia
- Trial name
- DKDA (NCT04763785)
- Testing
- Corneal tomography with Eyestar 900, Corneal tomography with Pentacam, Biometry with IOL-Master
- Where
- Switzerland
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Eyelid Diseases, Ptosis, Eyelid
Effect of Upper Eyelid Surgeries on Corneal Characteristics
The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient.
- Trial name
- NCT05750251
- Testing
- levator muscle resection surgery, Müller's muscle-conjuctival resection surgery, full-thickness anterior blepharotomy surgery
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
Myopia
Corneal Topography Asymmetry Indices Changes After Corneal Refractive Surgery
To evaluate the changes that occur in the corneal indices after corneal refractive surgery either PRK or LASIK.
- Trial name
- NCT04589091
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Keratoconus, Stable
Evaluation of Morphology Abnormal Cornea Stability With Corneal Biomechanical
To evaluate the corneal biomechanical properties of stable eyes with abnormal morphology, and introduce a biomechanical stable index to evaluate the stability of the eyes with abnormal morphology at the first diagnosis.
- Trial name
- NCT05748002
- Testing
- Pentacam and Corvis ST
- Where
- China
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Keratoconus, Pellucid Marginal Degeneration
Corneal Cross Linking and Topography Guided Excimer Laser Treatment
Topography guided laser treatment enables the surgeon to correct higher order aberrations in corneas with irregular astigmatism.
- Trial name
- NCT01682993
- Testing
- Topography guided Excimer Laser treatment and Corneal Cross Linking, Corneal Cross Linking
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Corneal Ectasia, Keratoconus
KeratoConus Data Acquisition With Topography and Aberrometry
This observational study aims to collect real-world wavefront aberrometry and corneal/scleral topography data from individuals with keratoconus and other corneal ectatic disorders.
- Trial name
- KC-DATA (NCT06859398)
- Testing
- Ocular Topography and Wavefront Aberrometry
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 52 people
- Sponsor
- Azalea Vision
Primary Pterygium, Astigmatism
Preoperative and Postoperative Refractive and Topographic Evaluation in Patients With Primary Pterygium: Comparison of Two Surgical Techniques
This study evaluated changes in refractive status and corneal topography before and after surgical treatment of primary pterygium.
- Trial name
- RETOP (NCT07742995)
- Testing
- Conjunctival Autograft, Amniotic Membrane Transplantation
- Volunteers
- 78 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Keratoconus
Reliability of Topography Measurements in Keratoconus
The purpose of this study is to assess the reliability and repeatability of the parameters obtained using the Galilei dual-scheimpflug corneal topographer for monitoring progression in eyes with keratoconus.
- Trial name
- NCT03511495
- Testing
- Galilei Corneal Topographer
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Pregnancy Related
Comparing Anterior Segment Parameters During Pregnancy and Post-Pregnancy
The aim of this study is to evaluate anterior segment changes during and after pregnancy, and compare them with non pregnant healty women
- Trial name
- NCT05175729
- Testing
- Comprehensive Ophthalmologic Examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Keratoconus
PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in Keratoconus
Keratoconus causes irregular astigmatism and reduced vision. Epi-off corneal crosslinking (CXL) stabilizes the cornea but often leaves higher-order aberrations uncorrected.
- Trial name
- PRoTECT (NCT07372911)
- Testing
- Schwind AMARIS excimer laser, Corneal collagen crosslinking epi-off accelerated
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Surgical Procedure, Unspecified
Corneal Cross-linking and Refractive Surface Ablation in Patients With Asymmetric Corneas
The purpose of this study is to evaluate safety and efficacy of corneal cross-linking and photorefractive keratectomy for refractive correction in patients with bilateral asymmetric topography.
- Trial name
- NCT02943967
- Testing
- CXL + PRK group, PRK group
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cornea, Refraction Error
Corneal Topography and High Order Aberrations in Regular Contraceptive Pills
Effect of regular usage of contraceptive pills on corneal topography and corneal high-order aberrations
- Trial name
- NCT07693673
- Testing
- Hormonal Contraception, Combined Oral Contraceptive (COC)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Elshimaa A.Mateen
Cornea
Assessment of Corneal Topography and Densitometry in Rheumatoid Patients
Corneal transparency is a result of its unique ultrastructure with collagen fibrils regularity, integrity of connective tissue, and balanced keratocyte components.
- Trial name
- NCT06759207
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University