Clinical trials: Coronary Artery Bypass
Heart Failure
Autologous Atrial Appendage Derived Cells in the Treatment of Heart Failure
This study aims to evaluate the safety and clinical feasibility of epicardially delivered autologous atrial appendage micrografts in the treatment of heart failure.
- Trial name
- NCT02672163
- Testing
- CABG surgery, AADC therapy
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Helsinki University Central Hospital
Atrial Fibrillation, Coronary Artery Disease
Management of New-Onset Postoperative Atrial Fibrillation
One common occurrence following open heart surgery is an irregular rhythm from the top chambers of the heart known as atrial fibrillation (afib or AF).
- Conditions
- Atrial Fibrillation, Coronary Artery Disease, Post Operative Arrythmia
- Trial name
- Monitor-AF (NCT01395836)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Emory University
Coronary Artery Bypass Graft
High Frequency Ventilation During Off Pump Coronary Artery Bypass Graft (CABG)
This study is to test the safety of high frequency-low volume ventilation during off pump coronary artery bypass as reflected in the near infrared spectroscopy values for cerebral oxygenation.
- Trial name
- VHF (NCT00863044)
- Testing
- Apnea, High frequency ventilation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Montreal Heart Institute
Cardiac Disease
The Effects of Neurophysiological Facilitation Techniques After Coronary Artery Bypass Graft Surgery
The aim of the study is to investigate the effects of neurophysiological facilitation techniques, applied in addition to Phase I cardiac rehabilitation in the early postoperative period after coronary artery bypass graft (CABG)…
- Trial name
- NCT06640699
- Testing
- exercise
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Coronary Artery Disease
Statin Recapture Therapy Before Coronary Artery Bypass Grafting
Patients with coronary artery disease requiring coronary artery bypass grafting (CABG) are at risk for postoperative complications after surgery.
- Trial name
- StaRT-CABG (NCT01715714)
- Testing
- Statin Recapture Therapy
- Where
- 10 sites in Germany
- Volunteers
- 2,630 people
- Sponsor
- University of Cologne
Coronary Artery Disease, Sleep Disorder
The Effect of Eye Mask Applied on Patients Undergoing Coronary Artery Bypass Graft Surgery
Introduction: Coronary Artery Bypass Graft (CABG) performed with open heart surgery technique is a successful operation in the treatment of cardiovascular diseases.
- Conditions
- Coronary Artery Disease, Sleep Disorder, Pain, Postoperative
- Trial name
- NCT06010498
- Testing
- eye mask, standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
CABG-patients, Saphenectomy
Clinical Impact of Surgical Wound Morbidity According to the Type of Saphenous Vein Harvesting Technique (Endoscopic vs. Open) in Patients Undergoing Myocardial Revascularization Surgery
The goal of this clinical trial is to compare two different techniques: endoscopic saphenous vein harvesting versus conventional open harvesting in patients undergoing coronary artery bypass grafting, either alone or in…
- Conditions
- CABG-patients, Saphenectomy, Endoscopic Surgery, Wound Complications
- Trial name
- EndOSiC (NCT07002658)
- Testing
- Harvesting of the saphenous vein graft
- Where
- Spain
- Volunteers
- 356 people
- Sponsor
- Hospital San Carlos, Madrid
Coronary Artery Disease
Collagen-thrombin Matrix Efficacy During Cardiac Surgery: a Prospective Randomized Controlled Trial
In this prospective open-label randomized trial, 160 patients with elective off-pump coronary artery bypass (OPCAB) surgery were enrolled.
- Trial name
- NCT04310150
- Testing
- Collastat, Floseal
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Low Cardiac Output Syndrome, Transposition of Great Vessels
Nitric Oxide During Bypass for Arterial Switch Operation
This trial will test if adding nitric oxide (NO) gas to the cardiopulmonary bypass (CPB) circuit in infants undergoing an arterial switch operation (ASO) for Transposition of the Great Arteries (TGA) changes the incidence of…
- Trial name
- NASO (NCT03661385)
- Testing
- Nitric Oxide
- Where
- 4 sites in Australia, Canada and 2 more
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Coronary Artery Bypass
Noninvasive Ventilation After Coronary Bypass Grafting
This is a prospective, quantitative, randomized, crossover study. Were included in this study 10 people in the Intensive Care Unit at University Hospital in Uberlandia, on the first day of the postoperative coronary artery bypass…
- Trial name
- Physiotherapy (NCT02352376)
- Testing
- Conventional ventilator, Specific ventilator
- Volunteers
- 10 people
- Sponsor
- Federal University of Uberlandia
Quantitative Flow Reserve, Minimally Invasive Coronary Surgery
The Impact of Preoperative Quantitative Flow Reserve (QFR) on Early Postoperative Radial Artery Graft Outcomes in Coronary Artery Bypass Grafting
The goal of this observational study is to learn about the long-term effects of Quantitative Flow Reserve (QFR) assessment in patients undergoing Coronary Artery Bypass Grafting (CABG).
- Conditions
- Quantitative Flow Reserve, Minimally Invasive Coronary Surgery, Radial Artery
- Trial name
- QFR-RADIAL (NCT07669987)
- Testing
- Observational
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Peking University Third Hospital
Coronary Artery Disease
Outcomes of Angiotensin Converting Enzyme Inhibitor Management Strategies Prior to Coronary Artery Bypass
Coronary artery disease is a leading cause of death, hospitalization, and health care costs in developed nations. Coronary revascularization with coronary artery bypass graft (CABG) surgery improves the long term survival in…
- Trial name
- COMPACT (NCT02096406)
- Testing
- ACE/ARB continuation, ACE/ARB withdrawal
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- University of Alberta
Cardiac Surgery, Coronary Artery Bypass Grafting
Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery
The purpose of the present research study is to investigate the pharmacokinetics, as well as safety, tolerability and pharmacodynamics of different ascending dosing regimens of AP214 in patients undergoing cardiac surgery.
- Conditions
- Cardiac Surgery, Coronary Artery Bypass Grafting, Valve Surgery, Aortic Root or Ascending Aortic Aneurysm Repair Surgery
- Trial name
- NCT00903604
- Testing
- AP214
- Where
- 2 sites in Denmark
- Volunteers
- 42 people
- Sponsor
- Action Pharma A/S
Ischemic Heart Disease, Atrial Fibrillation
Omega 3 Fatty Acid Efficiency for Prevention of Atrial Fibrillation After Coronary Artery Bypass Grafting
The purpose of this study is to evaluate efficacy of Polyunsaturated Fatty Acid for the prevention of Atrial Fibrillation and anti-inflammatory effects in patients after CABG surgery
- Trial name
- NCT01175330
- Testing
- Omega-3 fish oil emulsion (Omegaven), Intralipid
- Where
- Russia
- Volunteers
- 39 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Reduced Left Ventricular Function Defined as LVEF < 50%, Regional Left Ventricular Wall Motion Abnormalities
DESWT-Pilot Study on the Safety of Myocardial Regeneration by Direct Epicardial Shock Wave Therapy in Combination With Coronary Artery Bypass Grafting
Study purpose: To examine the safety of myocardial regeneration by direct epicardial shock wave therapy in combination with coronary artery bypass grafting.
- Trial name
- DESWT (NCT00741065)
- Testing
- Direct Epicardial Shock Wave Therapy
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Cardiac Regeneration Technologies, LLC
Coronary Artery Disease, Ischemia
Coronary Steal Via Natural Internal Mammary Artery-To-Coronary Artery Bypasses
CORONARY ARTERY DISEASE AND THE BENEFIT OF BYPASSES Despite considerable advances in medicine, cardiovascular diseases remain the number one cause of death globally.
- Trial name
- CIMA (NCT02332564)
- Testing
- Coronary Artery Balloon Occlusion for Determination of Collateral Flow Index
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Bypass Graft and/or Aortic Valve Replacement Surgery
Sugammadex and Decreased Time to Extubation
The purpose of this study is to demonstrate faster time to extubation after arrival in the cardiothoracic intensive care unit (ICU) in patients undergoing isolated coronary artery bypass grafting (CABG), AVR and AVR/CABG…
- Trial name
- NCT03196167
- Testing
- Sugammadex
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
Coronary Artery Disease
Coronary Artery and Coronary Artery Bypass Graft Imaging Using a Specialized Catheter and Computed Tomography
The present study relates to a new approach to coronary artery and coronary artery by-pass graft imaging, and more particularly to computed tomographic angiography following an aortic root injection of a low amount of contrast…
- Trial name
- NCT00474565
- Testing
- Placement of an aortic root pigtail catheter.
- Where
- United States
- Sponsor
- Corewell Health East
Thoracic Surgery, Cardiac Surgery
Comparison of Two Potassium Targets Within the Normal Range in Intensive Care Patients
Rationale: It is well known that distinctly abnormal blood potassium values can cause serious complications such as cardiac arrhythmias.
- Conditions
- Thoracic Surgery, Cardiac Surgery, Critically Ill
- Trial name
- GRIP-COMPASS (NCT01085071)
- Testing
- Potassium Chloride
- Where
- Netherlands
- Volunteers
- 1,225 people
- Sponsor
- University Medical Center Groningen
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