Clinical trials: Coronary Interventions
Cardiovascular Diseases, Heart Diseases
Evaluating the Effectiveness of a Family Heart Health Educational Program (The FIT-Heart Study)
The primary objective of the FIT Heart Study was to test the effectiveness of a hospital-based standardized screening and educational intervention targeted to family members of patients hospitalized with CVD, to increase…
- Trial name
- FIT-Heart (NCT00728637)
- Testing
- Family Passport to Heart Health Program, General Educational Materials
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Columbia University
Anxiety
The Effect of Music on Anxiety in the Appointment Period
The goal of this randomized clinical trial is to learn if musical intervention can reduce anxiety on patients and doctors in the appointment period.
- Trial name
- NCT06590363
- Testing
- Listening to zen music
- Where
- Portugal
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde de Coimbra, EPE
Myocardial Infarction
Complete Lesion Versus Culprit Lesion Revascularization
To investigate the clinical outcomes of acute myocardial infarction (AMI) patients with multivessel disease undergoing percutaneous coronary intervention (PCI) either in infarct-related artery only or in multivessel in Drug…
- Trial name
- COCUA (NCT01180218)
- Testing
- complete revascularization, Culprit revasularization
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Cardiovascular Diseases
Growing Healthy Hearts: A Pilot Randomized Control Trial to Test Gardening as an Intervention to Improve Health
The purpose of this study is to test the effect of group-based nutrition advice plus gardening (intervention) versus group-based nutrition advice alone on dietary intake of fruits and vegetables, physical activity, and lifetime…
- Trial name
- NCT04207268
- Testing
- Gardening and Nutrition Advice, Nutrition Advice
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Emotional Well-being, Psychological Stress
Feasibility of a Mind-Body Intervention for Optimism
This pilot study tests whether three brief mind-body activities can be delivered remotely to midlife adults, and whether they show early signs of improving cardiovascular health, emotional well-being, and stress.
- Conditions
- Emotional Well-being, Psychological Stress, Cardiovascular Risk
- Trial name
- NCT07862478
- Testing
- Emotional Well-Being Writing, Chair-Assisted Squats, Slow-Paced Breathing
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Acute Myocardial Infarction, Ischemia-reperfusion Injury
Combined Antioxidant Therapy Against Myocardial Reperfusion Injury. Phase I Study.
Background: Acute myocardial infarction (AMI) has remained a leading cause of mortality and disability worldwide. Although percutaneous coronary angioplasty (PCA) is the best treatment for these patients, paradoxically this…
- Conditions
- Acute Myocardial Infarction, Ischemia-reperfusion Injury, Reperfusion Injury, Myocardial, Reperfusion Arrhythmias
- Trial name
- NCT05215743
- Testing
- Antioxidant therapy, NaCl 0.9%
- Where
- Chile
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chile
Open Heart Surgery, Anxiety
Mindfulness-Based Nursing Care and Anxiety in Open Heart Surgery Patients
This randomized controlled trial aims to evaluate the effect of a mindfulness-based nursing intervention on anxiety levels and vital signs in patients undergoing open-heart surgery during the preoperative and early postoperative…
- Trial name
- OH-MIND (NCT07397052)
- Testing
- Mindfulness-Based Nursing Intervention Group, Standard Care Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mersin University
Medication Adherence, Heart Failure
SystemCHANGE™ Intervention on Medication Adherence in Older Adults With Heart Failure
The purpose of this pilot RCT study is to evaluate the acceptability and feasibility of a SystemCHANGE™ intervention to improve medication adherence in older adults with heart failure.
- Conditions
- Medication Adherence, Heart Failure, Aging
- Trial name
- ECHO (NCT03162848)
- Testing
- SystemCHANGE
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Heart Failure, Aortic Stenosis
The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis
The role of cardiac mechanics, circulating biomarkers and frailty in predicting outcomes in patients with aortic stenosis after aortic valve replacement (SCRABLES -The 2-Parts Study) Part I: Observational study to characterize…
- Trial name
- SCRABLES (NCT02856620)
- Testing
- Observational only
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Christine Henri
Overweight and Obesity, Cardiovascular Risk Factor
The Emirates Heart Health Project: A Family-based Diet and Exercise Intervention in Obese and Overweight Patients
Data from Abu Dhabi's Department of Health document that the leading cause of death among the population of the emirate of Abu Dhabi is cardiovascular disease (CVD).
- Trial name
- EHHP (NCT04688684)
- Testing
- Family-based diet and exercise intervention
- Where
- United Arab Emirates
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Coronary Artery Disease
Clinical and Procedural Outcomes of Ostial Left Anterior Descending Artery Intervention With or Without Crossover to Left-main
Prospective interventional study evaluating clinical and procedural outcomes of patients with ostial left anterior descending artery lesion PCI alone or crossover with left main artery
- Trial name
- NCT05933473
- Testing
- Percutaneous coronary intervention
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stress, Relaxation
Effects of Nature-Based Virtual Reality and Binaural Beats on Heart Rate Variability and Relaxation
The VRELAX study is a non-clinical sub-study within the "Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients"- research program (DESTRESS…
- Conditions
- Stress, Relaxation, Virtual Reality, Binaural Beats
- Trial name
- VRELAX (NCT07431918)
- Testing
- Nature-Based Virtual Reality With Binaural Beats
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Heart and Brain Research Group, Germany
Anxiety, Chest Tube Removal
Virtual Reality-Based Breathing Yoga Before Chest Tube Removal After Cardiac Surgery
This randomized controlled trial was conducted to evaluate the effect of virtual reality-based breathing yoga applied before chest tube removal on pain and anxiety in patients after cardiac surgery.
- Conditions
- Anxiety, Chest Tube Removal, Pain After Surgery
- Trial name
- NCT07794709
- Testing
- Virtual Reality-Based Breathing Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sennur Kula Şahin
Heart Failure With Preserved Ejection Fraction
PeRsonalIzed remOtely Guided Preventive exeRcIse Therapy for a healThY Heart
In the PRIORITY study, we aim to provide the clinical evidence base for the use of a new hybrid exercise intervention, which includes remotely guided home-based exercise, as an accessible, clinical and cost-effective treatment to…
- Trial name
- PRIORITY (NCT04745013)
- Testing
- PRIORITY, Usual care
- Where
- 3 sites in Belgium
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI), Dual Anti-platelet Therapy
Aspirin-Free Strategy After 3-6 Month Dual Antiplatelet Therapy in Acute Coronary Syndrome
This randomized controlled trial aims to evaluate the safety and efficacy of an aspirin-free strategy after 3-6 months of dual antiplatelet therapy (DAPT) in patients with acute coronary syndrome (ACS) who have undergone complete…
- Trial name
- NCT07736196
- Testing
- Aspirin-Free Strategy, Dual Antiplatelet Therapy
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Assiut University
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetes Mellitus, Type 2, Coronary Artery Disease
Optimizing Audit and Feedback for Primary Care
There remains a large gap between ideal and actual care provided to patients with chronic diseases. Performance feedback reports are often used as a foundation for quality improvement interventions.
- Trial name
- NCT00996645
- Testing
- Worksheet to facilitate goal-setting and action plans
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Obesity
Test of an Intervention to Increase Physical Activity Among School Children
The specific aims of this study are to: 1) evaluate the impact of a novel intervention delivered via school-based physical education (PE) on adolescents who have a high sensitivity to exercise-induced negative affect; 2)…
- Trial name
- NCT01876602
- Testing
- feeling states exercise intervention
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Acute Coronary Syndrome
Clinical Study and Molecular Mechanism of Xuesaitong Soft Capsule in the Treatment of Acute Coronary Syndrome
To evaluate the platelet function, clinical efficacy, prognosis and safety of Xuesaitong soft capsule in the treatment of acute coronary syndrome, 50 patients with acute coronary syndrome after PCI were treated with Xuesaitong…
- Trial name
- NCT06618495
- Testing
- Xuesaitong soft capsule (main ingredient is Panax notoginseng saponins)
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xiyuan Hospital of China Academy of Chinese Medical Sciences
Heart Diseases, Coronary Disease
CES1 Carriers in the PAPI Study
This study builds, in part, upon preliminary results generated as part of the Pharmacogenomics Anti-Platelet Intervention (PAPI) Study (NCT00799396).
- Conditions
- Heart Diseases, Coronary Disease, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- NCT03188705
- Testing
- Clopidogrel, Aspirin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore