Clinical trials: Coronary Patient
Arrhythmias, Cardiac
Full Early Atrial Diagnostics in Single Chamber ICD Patients Using the DX Lead and Home Monitoring in Brazil.
To demonstrate the value and benefits of BIOTRONIK's exclusive DX technology in assessing the incidence of supraventricular arrhythmias, mainly atrial fibrillation (AF), in patients with an indication for single chamber ICDs.
- Trial name
- SAFE-DX-Home (NCT04869527)
- Testing
- BIOTRONIK ICDs with DX Technology
- Where
- 2 sites in Brazil
- Volunteers
- 56 people
- Sponsor
- Biotronik SE & Co. KG
Coronary Artery Disease, Myocardial Infarction
Randomized Study to Assess the Effect of ThRombus Aspiration on Flow Area in STEMI Patients
The purpose of the study it to evaluate whether primary percutaneous coronary intervention (primary PCI) with a new thrombectomy device as compared to primary PCI without thrombectomy increases minimal flow area after stenting…
- Conditions
- Coronary Artery Disease, Myocardial Infarction, STEMI
- Trial name
- TROFI (NCT01271361)
- Testing
- primary PCI with thrombectomy, primary PCI without thrombectomy
- Where
- 5 sites in Denmark, France and 2 more
- Volunteers
- 140 people
- Sponsor
- Terumo Europe N.V.
Acute Coronary Syndrome, Cytokines
Vitamin D and Inflammatory Cytokine Levels After Acute Myocardial Infraction (MI)
Vitamin D is known to have immune-modulator effects including suppression of proinflammatory cytokine expression and regulation of immune cell activity.
- Trial name
- NCT01115842
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Acute Respiratory Distress Syndrome, Right Ventricular Dysfunction
Ventilator-induced Right Ventricular Injury During EIT-based PEEP Titration in Patients With ARDS
Right ventricular failure may be associated with mortality in patients with acute respiratory distress syndrome (ARDS). Mechanical ventilation may promote right ventricular failure by inducing alveolar overdistention and…
- Trial name
- RIGHTENARDS (NCT05583461)
- Testing
- Positive end-expiratory pressure titration
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- University of Padova
Heart Failure Patients Before and After ICD Implantation
Heart-focused Anxiety in Patients With Heart Failure and ICD
The aim of the present study is to measure heart-focused anxiety, general anxiety, depression, PTSD and quality of life as well as type D personality in patients with heart failure before and after the implantation of a…
- Trial name
- Anxiety-CHF (NCT02226770)
- Testing
- Implantable Cardioverter Defibrillator (ICD)
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- University Hospital, Saarland
Heart Surgery
Association Between S-LAAO and Adverse Cardiovascular Events Among Patients Undergoing Coronary Artery Bypass Grafting.
This is a prospective, single-center, randomized, active controlled, clinical trail to assess the efficacy and safety of surgical closure of left atrial appendage (LAA) in patients undergoing coronary artery bypass graft.
- Trial name
- NCT04108169
- Testing
- Left atrial appendage occlusion surgery
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Arrythmia
Effect of Sedative Agent on Reducing the Frequency of Arrhythmia in the Patients After Cardiac Surgery
Arrhythmias early in the recovery period after cardio thoracic surgery are common they develop in 11 to 40 percent of patients after coronary-artery bypass grafting.
- Trial name
- NCT05450497
- Testing
- Propofol, Dexmedetomidine, Dexmedetomidine and propofol
- Where
- Ukraine
- Volunteers
- 356 people
- Sponsor
- Anesthesia Research Group UA
Perioperative Myocardial Infarction, Disability
TEAMS (Troponin Elevation After Major Surgery) Study
Background to main study question: Cardiac complications are a common cause of morbidity after non-cardiac surgery. Patients with perioperative myocardial injury (both MI, and lower levels of cardiac troponin elevation)…
- Trial name
- TEAMS (NCT02146560)
- Where
- Canada
- Volunteers
- 267 people
- Sponsor
- University Health Network, Toronto
Atrial Fibrillation
New Oral Direct Anticoagulants in Patients 80 Years Old and Over : a Population Pharmacokinetics Study
Several new oral direct anticoagulants have been recently marketed. However, only a few, limited, studies have provided data about the pharmacology of new oral direct anticoagulants in older persons.
- Trial name
- ADAGE (NCT02464488)
- Testing
- Plasma drug concentrations
- Where
- 2 sites in France
- Volunteers
- 232 people
- Sponsor
- Hôpital Charles Foix
Coronary Artery Disease
e-NOBORI Observational Registry of Nobori DES
Title Prospective, single-arm, multi-centre, observational registry to further validate safety and efficacy of the Nobori® DES in real-world patients.
- Trial name
- e-NOBORI (NCT01261273)
- Where
- 257 sites in Austria, Bangladesh and 30 more
- Volunteers
- 18,000 people
- Sponsor
- Terumo Europe N.V.
Systolic Heart Failure, Diastolic Heart Failure
Psychosocial Patterns and Prognosis in Patients With Heart Failure
This prospective observational study is designed to confirm the prognostic and economic impact of depression in ambulatory patients with systolic or diastolic heart failure, to explore the impact of other psychosocial patterns…
- Trial name
- PANIC (NCT00709241)
- Where
- France
- Volunteers
- 325 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation, Deep Vein Thrombosis
Applying Pharmacogenetics to Warfarin Dosing in Chinese Patients
The purpose of this study is to determine whether pharmacogenetic guided dosing of warfarin is promising for the improvement of efficiency, therapeutic efficacy, and, especially, safety of warfarin therapy than a dosing regimen…
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism, Heart Valve Disease
- Trial name
- NCT01610141
- Testing
- Genotype-guided warfarin dosing, Non-genotype guided warfarin dosing
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease
A Study to Evaluate the Use of SOMVC001 (GALA) Vascular Conduit Preservation Solution in Patients Undergoing CABG (STEPS)
A prospective randomized, double-blinded, comparative within-person study to evaluate the use of SOMVC001 vs. heparin dosed saline in patients undergoing CABG.
- Trial name
- GALA (NCT02272582)
- Testing
- SOMVC001 Vascular Conduit Solution, Standard of care Heparin-dosed saline
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Perrault Louis P.
Minimally Invasive Cardiac Surgery
The Quality of Life and Patency Rate After Minimally Invasive Cardiac Surgery
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT05104320
- Testing
- MICS-CABG, sternotomy CABG
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Hyperlipidemias, Atherosclerosis
Percentage of Secondary Prevention Patients Treated to Their LDL-C Targets
A cholesterol/lipid profile screening project of high risk patients with hyperlipidaemia (secondary prevention) who already receive cholesterol-lowering therapy.
- Conditions
- Hyperlipidemias, Atherosclerosis, Coronary Heart Disease, Carotid Stenosis
- Trial name
- NCT00536796
- Where
- Austria
- Volunteers
- 1,096 people
- Sponsor
- AstraZeneca
Heart Failure, Cardio-Renal Syndrome
A Clinical Study of the Safety and Efficacy of a Wearable Device (CLS UF) That Delivers Continuous Administration of Glucose to Recirculated Peritoneal Dialysis Fluid for the Purpose of Ultrafiltration in Patients With Congestive Heart Failure
A single-center, prospective, non-randomized, clinical and first-in-human study. Each patient will be studied during a single treatment session of ten hours.
- Trial name
- NCT02772146
- Testing
- CLS UF
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Triomed AB
Bleeding
Novel Approaches in Preventing and Limiting Events III Trial (NAPLES III): Bivalirudin in High-risk Bleeding Patients
Bleeding occurring during percutaneous coronary interventions (PCI has now emerged as one of the most common complication of PCI and adversely affect in-hospital, short- and long-term outcome.As bivalirudin proved its…
- Trial name
- NAPLESIII (NCT01465503)
- Testing
- Bivalirudin, Unfractionated Heparin
- Where
- 2 sites in Italy
- Volunteers
- 837 people
- Sponsor
- Clinica Mediterranea
Hemorrhage
Indomethacin and Cardiac Bypass Surgery
Following signed informed consent, patients scheduled for elective cardiac surgery were randomly assigned to one of 3 groups to be given acetaminophen, Indomethacin or a combination of both immediately following induction and…
- Trial name
- NCT01073670
- Testing
- Indomethacin, Acetaminophen & Indomethacin, Acetaminophen
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Queen's University
Coronary Computed Tomography Angiography, Contrast Media
Optimization of Patient Preparation and Imaging Techniques for Cardiac CT
The goal of this clinical trial is to compare four different methods of reducing heart rate before cardiac imaging. The diagnostic imaging technique used in this study is called Computed Tomography (CT) of the coronary vessels…
- Conditions
- Coronary Computed Tomography Angiography, Contrast Media, Cardiac Output
- Trial name
- NCT06879769
- Testing
- Metoprolol I.V., Metoprolol I.V. and 1 hour waiting., Music Intervention, Seloken (Recordati) orally and Metoprolol I.V.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska University Hospital
ST Elevation Myocardial Infarction, Myocardial Infarction
OCT Versus Angiography for Culprit Lesion Revascularization in Acute Myocardial Infarction PatiEnts
The aim of the study is to compare clinical outcomes between optical coherence tomography-guided versus angiography-guided percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI).
- Trial name
- FRAME-AMI3 (NCT06227754)
- Testing
- Angiography-guided PCI group, Optical coherence tomography-guided PCI group
- Where
- 18 sites in South Korea
- Volunteers
- 1,500 people
- Sponsor
- Chonnam National University Hospital
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