Clinical trials: Coronary Patient
Acute Coronary Syndrome
Central Apnea in Patients Receiving Ticagrelor
all patients with a left ventricular ejection fraction superior or equal to 50% less than 2 years after an acute coronary event and receiving ticagrelor will undergo a sleep polygraphy
- Trial name
- NCT03540459
- Testing
- sleep polygraphy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Les Grands Prés
Out-of-hospital Cardiac Arrest (OHCA)
Execution of Prehospital Transesophageal Echocardiography During Cardiopulmonary Resuscitation in Patients With Out-of-hospital Cardiac Arrest
Out-of-hospital cardiac arrest (OHCA) remains a major global public health challenge. Despite continuous advancements in resuscitation strategies, overall survival rates remain low.
- Trial name
- EXECT-CPR-2 (NCT07909642)
- Testing
- Transesophageal Echocardiography-Guided Chest Compression, Conventional Cardiopulmonary Resuscitation
- Where
- Taiwan
- Volunteers
- 204 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiomyopathy
Quantitive LGE Mass in Prediction of SCD in NICM Patients With Severe Cardiac Dysfunction
The purpose of this study is to establish a quantitative LGE mass based scoring system (including LGE mass on cardiac magnetic resonance , clinical features, specific medical histories, et al) for risk prediction of sudden…
- Trial name
- NCT02757742
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Fu Wai Hospital, Beijing, China
Platelet Reactivity
Ticagrelor and Clopidogrel on Platelet Effects in Chinese Patients With Stable Coronary Artery Disease
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor reduces thrombotic events in patients with coronary artery disease, but these benefits come at the expense of increased risk of bleeding when compared with…
- Trial name
- NCT04001894
- Testing
- Ticagrelor 90mg, Clopidogrel 75mg
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Heart Failure
Non-invasive Pressure-Volume Analysis (NIPVA)
If the heart fails to pump a sufficient amount of blood, it is crucial to know why in order to provide the best treatment. Pressure-volume analysis is the gold standard for evaluating the heart's pumping function.
- Trial name
- NIPVA (NCT01960894)
- Where
- United Kingdom
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Imperial College London
High-Risk Percutaneous Coronary Intervention (High-risk PCI), Left Ventricular Assist Devices
Interventional Left Ventricular Assist System for PCI in CHIP Patients
Mechanical circulatory support (MCS) is a life-sustaining therapy first introduced in the 1950s. After six decades of development, it now serves as a critical bridge therapy for patients with acute cardiac events and end-stage…
- Trial name
- NCT07053618
- Testing
- Implantation of the VADLINK Percutaneous Left Ventricular Assist Device, VA-ECMO
- Where
- 15 sites in China
- Volunteers
- 286 people
- Sponsor
- Suzhou Hengruihongyuan Medical Technology Co. LTD
Diabetes Mellitus
Research on the Correlation Among Magnetocardiography Patterns and Known Cardiovascular Risk Factors in Diabetic Patients
The purpose of this study is to evaluate the correlation among magnetocardiography (MCG) patterns and various known cardiovascular risk factors.
- Trial name
- NCT00989924
- Where
- Taiwan
- Volunteers
- 1,100 people
- Sponsor
- National Taiwan University Hospital
Tachycardia, Ventricular
PAtient NOtifier Feature for Reduction of Anxiety
This study is intended to look at the effect of the SJM vibrating Patient Notifier™ system, which will warn the patient of possible failures of the implanted system, on reducing patient device related anxiety
- Trial name
- Panoramic (NCT00559559)
- Testing
- ICD implant + Patient Notifier turned OFF, ICD Implant + Patient Notifier turned ON
- Where
- Switzerland
- Volunteers
- 362 people
- Sponsor
- Abbott Medical Devices
Mamma Carcinoma, Heart Failure
Response to Influenza Virus Vaccination in Patients Immunocompromised Due to Chemotherapy
Patients treated with chemotherapy or immunosuppressives are at higher risk of influenza infection and mortality and morbidity are higher compared to healthy adults.
- Trial name
- RIFLUVAC (NCT01000246)
- Testing
- influenza virus vaccine (influvac or vaxigrip)
- Where
- 8 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- St. Antonius Hospital
Heart Failure, Left Ventricular Assist Device
Prognostic Value of BNP in MCS - a 25 Year Follow up Study
A biobank has been created to investigate the prognostic value of biomarkers (mainly BNP) in patients implanted with durable mechanical assist devices comparing patients with advanced HF supported by MCS with those who are…
- Conditions
- Heart Failure, Left Ventricular Assist Device, Prognosis, Durable Mechanical Support Device
- Trial name
- NCT04377854
- Testing
- Observation. No intervention per se., 2) Observation and collection and of blood sample
- Where
- Denmark
- Volunteers
- 1,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gastrointestinal Bleeding
Early Endoscopy for Acute Upper Gastrointestinal Bleeding in Acute Coronary Syndrome Patients
The primary aim of this study is to compare efficacy of "early endoscopy" and "non-endoscopic treatment" for management of acute upper gastrointestinal (UGI) bleeding in patients with recent acute coronary syndrome (ACS).
- Trial name
- NCT02618980
- Testing
- endoscopic hemostasis
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- Far Eastern Memorial Hospital
Obstructive Hypertrophic Cardiomyopathy
A Study to Learn More About How Well Aficamten Works in Japanese Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy
Researchers are looking for a better way to treat Japanese people who have symptomatic obstructive hypertrophic cardiomyopathy (symptomatic oHCM).
- Trial name
- CAMELLIA-HCM (NCT07023341)
- Testing
- BAY3723113
- Where
- 23 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Bayer
Acute Coronary Syndrome
Genotype Guided Versus Conventional Approach in Selection of Oral P2Y12 Receptor Blocker in Chinese Patients Suffering From Acute Coronary Syndrome
This study aims to compare the outcome between genotype guided versus clinical guided approach in selection of oral P2Y12 receptor blocker in Chinese patients suffering from acute coronary syndrome.
- Trial name
- NCT01994941
- Testing
- Clopidogrel, Ticagrelor
- Where
- Hong Kong
- Volunteers
- 133 people
- Sponsor
- The University of Hong Kong
Metabolism and Nutrition Disorders
The CoCoS Interventional Trial: Caloric Control in Cardiac Surgery Patients
Background: Malnutrition is widespread among cardiac surgery patients and is independently related to an adverse postoperative evolution or outcome.
- Trial name
- NCT02902341
- Testing
- Nutrition Therapy, Control
- Volunteers
- 351 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer, Cardiac Toxicity
Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving Trastuzumab
RATIONALE: Lisinopril or Coreg CR®, may help reduce side effects caused by trastuzumab. It is not yet known whether lisinopril or Coreg CR® are more effective than a placebo in reducing side effects caused by trastuzumab.
- Trial name
- NCT01009918
- Testing
- Coreg CR®, lisinopril
- Where
- 174 sites in United States
- Volunteers
- 468 people
- Sponsor
- University of South Florida
Cardiac Surgery
Cytomegalovirus Reactivation in Non Immunocompromised Patients Undergoing Cardiac Surgery
We hypothesized that the stress of cardiac surgery and cardiopulmonary bypass can cause reactivation of a latent CMV infection and that reactivation might be more prevalent in patients with complicated post-operative course.
- Trial name
- NCT02527291
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Soroka University Medical Center
Heart Failure
Study of Renal Denervation in Patients With Heart Failure
Congestive heart failure is a common disorder in which the heart cannot pump enough blood to meet the needs of the rest of the body.
- Trial name
- PRESERVE (NCT01954160)
- Testing
- Symplicity Renal Denervation
- Where
- 12 sites in United States
- Volunteers
- 5 people
- Sponsor
- Adrian Hernandez
Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent…
- Trial name
- NCT07308860
- Testing
- FFR-guided PCI, CABG
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Atrial Fibrillation, Persistent, Atrial Fibrillation
AF-FLOW Registry to Evaluate Electrographic Flow Mapping in Patients Undergoing Ablation for Atrial Fibrillation
This post-market global registry will evaluate the ability of Electrographic Flow (EGF™) mapping to identify atrial fibrillation (AF) sources and guide ablation therapy in patients with atrial fibrillation in real-world setting.
- Conditions
- Atrial Fibrillation, Persistent, Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases
- Trial name
- NCT05481359
- Testing
- Electrographic Flow™ (EGF) mapping and ablation
- Where
- 5 sites in United States, Netherlands and 1 more
- Volunteers
- 25 people
- Sponsor
- Ablacon, Inc.
Coronary Artery Disease (CAD), Oxidative Stress
Ginger in the Modulation of Inflammatory Cytokines and Oxidative Stress in Patients With Coronary Artery Disease
The study aims to evaluate the effect of ginger supplementation on inflammatory cytokines and markers of oxidative stress in patients with Coronary Artery Disease (CAD).
- Conditions
- Coronary Artery Disease (CAD), Oxidative Stress, Inflammation
- Trial name
- NCT07596979
- Testing
- Ginger
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal Fluminense
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