Clinical trials: Coronary Patient
Hypertension, Arterial Hypertension
Effects of Different Telerehabilitation Methods In Patients With Hypertension (TELE-HT)
This study aims to compare two different ways of providing exercise therapy to people with high blood pressure (hypertension) through digital technology.
- Conditions
- Hypertension, Arterial Hypertension, Systemic Hypertension
- Trial name
- TELE-HT (NCT07363447)
- Testing
- Synchronous Cardiac Telerehabilitation, Asynchronous Cardiac Telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Hacettepe University
Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder)
Evaluation of the Patient Deterioration Warning System
The overall goal of the project is to reduce the number of unexpected patient deteriorations by 50% at Emergency Departments (ED) by investigating if the novel Patient Deterioration Warning Systems (PDWS), can improve clinicians'…
- Conditions
- Patient Transfer to Intensive Care Unit (Procedure), Respiratory Arrest (Disorder), Cardiac Arrest (Disorder), Patient Died in Hospital (Finding)
- Trial name
- PDWS (NCT03375658)
- Testing
- PDWS Intervension
- Where
- 2 sites in Denmark
- Volunteers
- 6,500 people
- Sponsor
- University of Southern Denmark
Advanced Refractory Left Ventricular Heart Failure
MOMENTUM 3 IDE Clinical Study Protocol
The objective of the study is to evaluate the safety and effectiveness of the HM3 LVAS by demonstrating non-inferiority to the HMII LVAS (HMII) when used for the treatment of advanced, refractory, left ventricular heart failure.
- Trial name
- HM3™ (NCT02224755)
- Testing
- HeartMate 3 LVAS, HeartMate II LVAS
- Where
- 69 sites in United States
- Volunteers
- 1,028 people
- Sponsor
- Abbott Medical Devices
Myocardial Injury
Remote Ischemic Preconditioning in Coronary Artery Bypass Grafting With Cold Crystalloid Cardioplegic Arrest
Remote ischemic preconditioning (RIPC) with transient upper limb ischemia/reperfusion reduces myocardial injury in patients undergoing on-pump coronary artery bypass (CABG) surgery with cross-clamp fibrillation or blood…
- Trial name
- NCT01406678
- Testing
- RIPC, Control, isoflurane+sufentanil anesthesia
- Where
- Germany
- Volunteers
- 1,204 people
- Sponsor
- University Hospital, Essen
Covid19, Right Ventricular Dysfunction
Right Ventricular Dysfunction in Ventilated Patients With COVID-19
Using echocardiography to investigate the incidence of RV dysfunction in ventilated patients with COVID-19.
- Conditions
- Covid19, Right Ventricular Dysfunction, ARDS
- Trial name
- COVID-RV (NCT04764032)
- Testing
- Echocardiography
- Where
- 11 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- University of Glasgow
Heart Failure, Diabetes
Safety and Effectiveness of SGLT-2 Inhibitors in Patients With Heart Failure and Diabetes
Patients with diabetes are at increased risk of developing heart failure (HF) which can lead to increased shortness of breath, reduced ability to exercise and in some cases premature death as the heart becomes less efficient at…
- Trial name
- REFORM (NCT02397421)
- Testing
- Dapagliflozin
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- University of Dundee
Cardiovascular; Attack
Very Early Versus Delayed Angiography +/- Intervention on Outcomes in Patients With NSTEMI
Prospective, open, multicentre, randomised controlled trial in patients with higher risk non-ST elevation myocardial infarction acute coronary syndrome
- Trial name
- RapidNSTEMI (NCT03707314)
- Testing
- Angiography with follow-on revascularisation if indicated
- Where
- United Kingdom
- Volunteers
- 425 people
- Sponsor
- University Hospitals, Leicester
Atrial Fibrillation, Paroxysmal
Clinical Efficacy of Potassium Canrenoate in Sinus Rhythm Restoration Among Patients With Atrial Fibrillation.
The purpose of this randomized, double blind, placebo-controlled, superiority clinical trial was to assess clinical efficacy of potassium canrenoate - canrenone in rapid conversion of atrial fibrillation to sinus rhythm.
- Trial name
- CANREN-AF (NCT03536806)
- Testing
- Saline 0.9%, Canrenone
- Volunteers
- 80 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Coronary Artery Disease, Chronic Kidney Diseases
Intravascular Ultrasound-Guided PCI in Patients With Chronic Kidney Disease
The IVUS-CKD study is a prospective, randomized controlled, multicenter trial to determine whether the intravascular ultrasound (IVUS)-guided percutaneous coronary intervention is superior to the angiography-guidance in chronic…
- Trial name
- IVUS-CKD (NCT06567938)
- Testing
- Percutaneous coronary intervention
- Where
- China
- Volunteers
- 1,528 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Out of Hospital Cardiac Arrest
Continuous Chest Compressions vs AHA Standard CPR of 30:2
The primary aim of the trial is to compare survival to hospital discharge after continuous chest compressions (CCC) versus standard American Heart Association (AHA) recommended cardiopulmonary resuscitation (CPR) with interrupted…
- Trial name
- CCC (NCT01372748)
- Testing
- Standard CPR, Continuous chest compressions
- Where
- 7 sites in United States, Canada
- Volunteers
- 23,711 people
- Sponsor
- University of Washington
Aortic Valve Stenosis
MRI in Transcatheter Aortic Valve Replacement Patients
The hypothesis is that SEV result in superior valvular hemodynamics (more pronounced during exercise) and exercise capacity relative to BEV.
- Trial name
- MRI-TAVR (NCT05603026)
- Testing
- Self-expanding valve (Medtronic Evolut FX), Balloon-expanding valve (Edwards Sapien 3 Ultra RESILIA)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University Hospitals Cleveland Medical Center
Cardiac Surgery
The Effect of Simple Needle Guide Device for Ultrasound-guided Internal Jugular Vein Catheterization in Cardiac Surgical Patients
The purpose of this study is to evaluate the effect of simple needle guide device for ultrasound-guided internal jugular vein catheterization in cardiac surgical patients
- Trial name
- NCT03390543
- Testing
- Sono with Device, sono only
- Where
- South Korea
- Sponsor
- Yonsei University
Ischemic Cardiomyopathy
Intracoronary or Intravenous Infusion Human Wharton' Jelly-derived Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy
The purpose of this study is to investigate the safety and efficacy of intracoronary or intravenous infusion human umbilical Wharton's jelly-derived Mesenchymal Stem Cell (WJMSC) in patients with ischemic cardiomyopathy secondary…
- Trial name
- WJ-ICMP Tria (NCT02368587)
- Volunteers
- 160 people
- Sponsor
- Navy General Hospital, Beijing
Aortic Stenosis, Transthyretin Amyloid Cardiomyopathy
Cardiac Amyloidosis in Patients With Aortic Stenosis
This study intends to conduct a prospective observation to investigate the prevalence of cardiac amyloidosis (CA) in patients with aortic stenosis (AS), compare the clinical characteristics between patients with isolated AS and…
- Trial name
- NCT07170306
- Testing
- transcatheter aortic valve replacement (TAVR)
- Volunteers
- 143 people
- Sponsor
- Shanghai Zhongshan Hospital
Pacemaker Complication, Arrhythmias, Cardiac
Association of Obesity and Cardiovascular Outcomes in Patients With Pacemaker
In this study, the investigators evaluated the association between various measures of adiposity [BMI and waist circumference (WC)] and clinical outcomes in Asian patients who underwent pacemaker insertion, using a nationwide…
- Conditions
- Pacemaker Complication, Arrhythmias, Cardiac, Obesity, Cardiovascular Morbidity
- Trial name
- Paradox (NCT05645978)
- Testing
- Pacemaker insertion
- Where
- South Korea
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
STEMI
Effect of Covid-19 Epidemic on Primary PCI in Patients With STEMI
The epidemic of covid-19 has spread all over the world and has a great impact on people's health and life. It is necessary to study the treatment of STEMI patients in the real world under the influence of the epidemic,which…
- Trial name
- NCT04427735
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Friendship Hospital
Coronary Artery Disease, Chronic Total Occlusion
CTO-PCI in Heart Failure Patients
The study investigates wheather CTO-PCI improves survival and heart failure related rehospitalization compared to optimal medical therapy (OMT).
- Conditions
- Coronary Artery Disease, Chronic Total Occlusion, Heart Failure
- Trial name
- CTO-HF (NCT05632653)
- Testing
- CTO-PCI
- Volunteers
- 783 people
- Sponsor
- Universitätsmedizin Mannheim
Angina Pectoris, Ischemic Heart Disease
Heart Rate Variability (HRV) Testing Compared With Exercise Stress Test in Hospitalized Patients With Chest Pain
There are many patients hospitalized for chest pain, which don't have high risk features that require invasive coronary angiography, but are considered intermediate risk and for which ischemic heart disease can not be excluded.
- Trial name
- NCT02530021
- Testing
- Heart rate monitor
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Community-Acquired Pneumonia, Exacerbation of Chronic Heart Failure
Feasibility and Outcomes of Older Patients Hospitalization
Hospitalization is a traumatic event for the patient and his family at any age nevertheless in the older age. One of its consequences is the difficulty to resume previous activity of daily living especially in older (over 75…
- Conditions
- Community-Acquired Pneumonia, Exacerbation of Chronic Heart Failure, Exacerbation of Chronic Obstructive Pulmonary Disease, Cellulitis
- Trial name
- NCT00489021
- Testing
- sub-acute hospitalization
- Volunteers
- 300 people
- Sponsor
- Hillel Yaffe Medical Center
Heart Failure With Reduced Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Ertugliflozin to Reduce Arrhythmic Burden in ICD/CRT patientS (ERASe-Trial) - a Phase III Study
The recent study is planned to investigate the impact of Ertugliflozin on total burden of ventricular arrhythmias. Further objectives will be number of therapeutic interventions of implanted devices, atrial fibrillation, heart…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Heart Failure With Mid Range Ejection Fraction, Implantable Cardioverter-Defibrillators, Cardiac Resynchronization Therapy
- Trial name
- ERASE (NCT04600921)
- Testing
- Ertugliflozin 5 mg
- Where
- 8 sites in Austria
- Volunteers
- 55 people
- Sponsor
- Medical University of Graz
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