Clinical trials: Coronary Vessel
Depression, Acute Coronary Syndrome
The Effect of MElatonin on Depression, Anxiety, CIrcadian and Sleep Disturbances in Patients After Acute Myocardial Syndrome
The objective of the study is to investigate whether prophylactic treatment with melatonin has an effect on depressive symptoms. Secondarily melatonin's effect on anxiety, sleep and circadian disturbances will be investigated.
- Trial name
- MEDACIS (NCT02451293)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- 6 sites in Denmark
- Volunteers
- 252 people
- Sponsor
- Zealand University Hospital
Coronary Disease
Bile Acids and Gut Microbiota as Potent Coronary Atheroma Risk Factors: a Prospective Study in Human
The purpose of this study is to describe the composition of bile acids and the gut microbiota comparing two populations: patients with coronary atheroma and the healthy subjects.
- Trial name
- MABAC (NCT02375893)
- Testing
- No intervention, Healthy subject
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation, Hemostasis
Vascular Closure With Novel External Compression Device: The LockeT Study
Single center, retrospective review study comparing Figure of Eight suture to LockeT, enrolling approximately 70 patients.
- Trial name
- NCT06199414
- Testing
- Venous Closure
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Statins, Myocardial Infarction
Statin Eligibility Prior to Myocardial InfarCtion
The study (Statin Eligibility Prior to myocardial infarction (MI) in Jordanians, StatinEPIC) is 1. Cross sectional 2. Non interventional 3. One encounter per patient. No follow up.
- Trial name
- StatinEPIC (NCT03485742)
- Testing
- No intervention
- Where
- 5 sites in Jordan
- Volunteers
- 740 people
- Sponsor
- Jordan Collaborating Cardiology Group
Hemodilution, Coronary Artery Disease
Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery
Hemodilution reduces concentrations of blood constituents: concentration of hemoglobin, red blood cells (hematocrit), physiological ions and coagulation factors that can contribute to impaired hemostasis and increasing the risk…
- Conditions
- Hemodilution, Coronary Artery Disease, Fluid Overload
- Trial name
- RAPPER-MAN (NCT04870073)
- Testing
- Retrograde autologous priming, Mannitol, Conventional Priming
- Where
- Canada
- Sponsor
- Hamilton Health Sciences Corporation
Coronary Artery Disease, Diabetes Mellitus
Effects of RF on Clopidogrel Resistance in Patients at High Cardiovascular Risk
Ramadan fasting (RF) has been shown to be associated with vascular and metabolic disorders including glycemic control and lipid profile. It may also alter pharmacologic properties of some medications.
- Trial name
- RFeCloR (NCT02624583)
- Where
- 2 sites in Tunisia
- Volunteers
- 98 people
- Sponsor
- University of Monastir
Aneurysm Aortic, Aneurysm Aortic Root
Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM)
The aim of the study is to analyse the resected portion of aneurysmatic ascending aorta in order to assess its strength to rupture, standardise the various measurements performed within the lab and try to correlate these…
- Trial name
- STORM (NCT07453251)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato
Cardiogenic Shock
ECMOsorb Trial - Impact of a VA-ECMO in Combination With CytoSorb in Critically Ill Patients With Cardiogenic Shock
In the ECMOsorb study the impact of a veno-arterial -ECMO in combination with an extracorporeal cytokine hemadsorption system in critically ill patients with cardiogenic shock is to be examined
- Trial name
- ECMOsorb (NCT05027529)
- Testing
- CytoSorb, VA-ECMO only
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- Christian Schulze
Microvascular Angina
Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis (MARINA)
The purpose of this study is to look at the effects of the drug Ranolazine compared to Placebo on symptoms of chest pain or chest tightness (known as angina), exercise endurance and ability, and changes in blood flow to the very…
- Trial name
- MARINA (NCT02147067)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Coronary Artery Disease
Comparison of the HyperQ Versus Conventional Electrocardiogram (ECG) to Detect Ischemia
The purpose of the investigation is to verify the efficiency of the HyperQ™ system in detecting exercise induced ischemia, with higher specificity and sensitivity than conventional ECG Stress testing.
- Trial name
- NCT00917800
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- West German Heart Center Essen
Stable Coronary Artery Disease
Prognostic Models for People With Stable Coronary Artery Disease
There is currently no published algorithm for secondary prevention prognosis of CHD that is representative of the England GP-registered population and that includes both symptomatic and asymptomatic patients (as identified…
- Trial name
- NCT01609465
- Where
- United Kingdom
- Volunteers
- 300,000 people
- Sponsor
- University College, London
Acute Coronary Syndrome, Chronic Heart Failure
Influenza Vaccination During Coronavirus Disease 2019 Outbreak After Acute Coronary Syndrome and Chronic Heart Failure
Study Description: Background: Well-known fact that the number of cardiovascular diseases is on the rise during influenza epidemic.
- Trial name
- IV-ACS&CHF (NCT05232292)
- Testing
- Ultrix Quadri
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Samara Regional Cardiology Dispensary
Cardiovascular Disease, Coronary Artery Calcification
7 Year Follow-up Study of the DanRisk Population
OBJECTIVES: To investigate the incidence of cardiovascular events as well as progression of coronary artery calcium (CAC) in healthy middle-aged subjects over a period of 7 years, and the relation to traditional as well as new…
- Conditions
- Cardiovascular Disease, Coronary Artery Calcification, Atherosclerosis
- Trial name
- NCT02913144
- Volunteers
- 1,257 people
- Sponsor
- Odense University Hospital
Transposition of Great Vessels, Surgery
MRI Study After Arterial Switch Operation in Patients With Transposition of the Great Arteries
This study involves adolescents operated with arterial switch procedure for transposition of the great arteries during the neonatal period.
- Trial name
- NCT01916499
- Testing
- 3 tesla magnetic resonance imaging findings; coronary artery status, 3 tesla magnetic resonance imaging findings; ventricular function and morphology
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Coronary Artery Disease (CAD), Ischemic Heart Disease
Coroflex® ISAR NEO PMCF Study
International, Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Coroflex® ISAR NEO coronary stent system to meet EU Medical Device…
- Trial name
- rEPIC07 (NCT05698732)
- Testing
- Coroflex® ISAR NEO coronary stent system
- Where
- 26 sites in France, Spain and 1 more
- Volunteers
- 3,000 people
- Sponsor
- Fundación EPIC
Coronary Heart Disease, Cardiovascular Risk Factor
Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
The aim of this study is to examine the reproducibility of postprandial coronary heart disease (CHD) risk marker and sleep responses to acute exercise bouts and to quantify the magnitude of individual variability in responses…
- Conditions
- Coronary Heart Disease, Cardiovascular Risk Factor, Arterial Stiffness, Blood Pressure
- Trial name
- NCT05022498
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Socioeconomic Status, Secondary Prevention
Socioeconomic Status, Secondary Prevention Activities and Recurrence After a Myocardial Infarction
This is a nationwide cohort study on real-world patients (n≈30,000) surviving a first myocardial infarction (MI) 2006-2013 and alive to attend a routine 1-year follow-up.
- Conditions
- Socioeconomic Status, Secondary Prevention, Myocardial Infarction, Cardiovascular Disease
- Trial name
- NCT04199663
- Volunteers
- 30,191 people
- Sponsor
- Karolinska Institutet
Atrial Fibrillation, Ischemic Heart Disease
Epicardial Fat Pads Ablation During Coronary Surgery
The aim of this prospective randomized study was to assess the efficacy of ablation of the ganglionated plexi localized in the epicardial fat pads for preventing recurrences of atrial tachyarrhythmia in patients with paroxysmal…
- Trial name
- NCT02984371
- Testing
- Coronary artery bypass grafting, Epicardial ganglionated plexi ablation, implantable loop recorder
- Where
- 2 sites in Russia
- Volunteers
- 264 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Heart Defects, Congenital, Hypertension, Pulmonary
Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery
This clinical trial will determine the safety and effectiveness of intravenous L-citrulline in children undergoing cardiopulmonary bypass during heart surgery.
- Trial name
- NCT00335244
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Asklepion Pharmaceuticals, LLC
Ischemic Heart Disease
Patterns of Antiacids Use in Patients With IHD Admitted to Department of Internal Medicine
There is substantial, continuing, and unexplained rise in prescribing of proton pump inhibitors. It is unknown whether their use in practice has corresponded to their licensed indications.
- Trial name
- NCT00392964
- Where
- 2 sites in Israel
- Volunteers
- 1,200 people
- Sponsor
- Rambam Health Care Campus