Clinical trials: Cortical Excitability
Brain Stimulation, Peripheral Nerve Stimulation
Glutamate Modulation of tDCS Over Premotor Cortex Combined With Peripheral Nerve Stimulation Promoted Observation-execution-related Cortical Excitability and Motor Learning
This study aimed to investigate whether concurrent tDCS over the PMC and PNS during action observation enhance observation-execution-related motor cortex excitability and improve motor performance, and to explore the underlying…
- Conditions
- Brain Stimulation, Peripheral Nerve Stimulation, Motor Observation, Cortical Excitability
- Trial name
- NCT06694909
- Testing
- tDCS + PNS with action observation, tDCS + PNS without action observation
- Where
- China
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Healthy Volunteers
Cortical Excitability Using Transcranial Magnetic Stimulation and Neuronavigation Device
This study has two main goals : to investigate the impact of aging on cortical excitability (CE) to investigate the impact of "state dependency" on CE, using a cognitive task and an emotional one.
- Trial name
- RC-TMS (NCT02596789)
- Testing
- TMS "Magpro®, Magventure Inc" device
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Transcutaneous Nerve Stimulation
Effect of Transcutaneous Nerve Stimulation on Primary Motor Cortex to Modulate Cortical Excitability and Hemodynamic Response During Implicit Motor Learning: A TMS and NIRS Study
Noninvasive brain stimulation was recently gradually be emphasized. The electrical current applied on scalp can effective modulate cortical excitability.
- Trial name
- NCT02115841
- Testing
- "Enraf-Nonius" Muscle stimulator
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Traumatic Brain Injury, Cortical Excitability
Cortical Excitability in Post-traumatic Epilepsy
To test whether measures of cortical excitability derived from motor cortex transcranial magnetic stimulation (TMS) in patients with traumatic brain injury reflect heightened excitability relative to healthy controls and whether…
- Conditions
- Traumatic Brain Injury, Cortical Excitability, Epilepsy
- Trial name
- NCT05517954
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mid-Atlantic Epilepsy and Sleep Center, LLC
Stroke
Paired Associative Stimulation in Stroke
Stroke is the third most common cause of death in the United States after heart disease and cancer, and the leading cause of long-term disability.
- Trial name
- NCT02586597
- Testing
- Transcranial magnetic stimulation & median nerve stimulation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Kinesiophobia, Motor Coordination or Function; Developmental Disorder
Influence of Kinesiophobia on the Excitability of Connections Parieto-frontal During a Pointing Movement in Humans
Objective(s) of the trial: Better understand the interaction between kinesiophobia and motor control. Main objective: To measure the influence of induced kinesiophobia on functional connectivity between the posterior…
- Conditions
- Kinesiophobia, Motor Coordination or Function; Developmental Disorder, Transcranial Magnetic Stimulation, Pain, Acute
- Trial name
- pIPS/M1 (NCT06125613)
- Testing
- Experimental
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Stroke
Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke
The purpose of this study is to investigate the effects of transcranial magnetic stimulation (TMS) on motor cortex excitability in individuals who have suffered stroke and to study the influence of the phase of the oscillatory…
- Trial name
- NCT04968743
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Parkinson Disease
Effects of Rhythmic Auditory Cueing on Stepping in Place in Patients With Parkinson's Disease
Patients with Parkinson's disease have internal rhythm dysfunction, which may affect the rhythmic movements such as walking. Poor regularity of the rhythmic movement may lead to freezing of gait.
- Trial name
- NCT03271736
- Testing
- Stepping-in-place exercise with external auditory cues, Transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- HsiuYun Chang
Healthy
Cortical Pharyngeal Area: Excitability, Facilitation and Plasticity in Healthy Subjects
The aims of this study are in four experimental sessions. The aims are: to characterize the excitability of the cortical pharyngeal area with pharyngeal pressure and electromyograms (EMGs), at rest, in awake healthy subjects; to…
- Trial name
- NCT00213382
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Incontinence, Constipation
Biofeedback and Cortical Excitability
Looking for a modification of the cortical excitability of the motor area corresponding to the external anal sphincter after biofeedback sessions.
- Trial name
- Biofeedback (NCT00653887)
- Testing
- Biofeedback
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Stroke
HAptic Neurofeedback Design for Stroke
Interventional study with minimal risks and constraints, prospective, monocentric.
- Trial name
- HANDS (NCT04130711)
- Testing
- Visual virtual Conditions, Standard EEG, Neurofeedback Training Stroke Patients
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Young Adults
Cortical Excitability and Typing Performance After Action Observation and Motor Execution
Goal: This study will aim to investigate the effects of different motor stimulation strategies-motor execution (ME) and action observation (AO)-on cortical excitability and typing performance in healthy individuals.
- Trial name
- NCT07009561
- Testing
- Motor Execution Typing Task, Action Observation of Typing Task
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Cortical Excitability, Motor Performance
The Effect of tDCS on Motor Performance and Cortical Excitability
In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS…
- Conditions
- Cortical Excitability, Motor Performance, tDCS
- Trial name
- NCT01740843
- Testing
- transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Healthy
Effects of Antiepileptic Drugs on Brain Excitability
This study will evaluate the usefulness of transcranial magnetic stimulation (TMS) in measuring cortical excitability. The cortex is the outer part of the brain.
- Trial name
- NCT00054990
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)