Clinical trials: Cost-Benefit Analysis
Radius Fractures, Aged
Cost-effectiveness, Volar Locking Plate or Non-operative Treatment Distal Radius Fracture
A cost-utility analysis based on an earlier published RCT comparing surgery with volar locking plate to non-operative treatment for the elderly with a displaced distal radius fracture.
- Conditions
- Radius Fractures, Aged, Cost-Benefit Analysis, Wrist Fracture
- Trial name
- HE-VOCAL (NCT06067074)
- Testing
- Volar Locking Plate, Plaster Cast
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Clift Lip, Cleft Palate
Description of Pain in Pediatric Patients With Cleft Lip and Palate Undergoing Alveolar Grafting Using Two Surgical Strategies: Stem Cells and Autogenous Iliac Crest Bone (Pain Evaluation in Children Undergoing Alveolar Grafting: Stem Cells vs. Iliac Crest Bone)
Study Objective The objective of this study was to evaluate and compare postoperative pain and hospital costs in pediatric patients with cleft lip and palate undergoing alveolar bone grafting surgery.
- Conditions
- Clift Lip, Cleft Palate, Alveolar Bone Loss, Postoperative Pain
- Trial name
- NCT07734974
- Testing
- Autogenous Iliac Crest Bone Grafting, Bioengineered Alveolar Grafting (SHED + Scaffold)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Sirio-Libanes
Chronic Pain, Musculoskeletal Pain
Implementation of a Behavioural Medicine Approach in Physical Therapy for Treatment of Chronic Pain
Implementation of a behavioral medicine (BM) approach in physical therapy (PT) for patients with persistent musculoskeletal pain is in accordance with the state of science.
- Trial name
- NCT03118453
- Testing
- Active implementation clinics, Passive implementation clinics
- Where
- 3 sites in Sweden
- Volunteers
- 109 people
- Sponsor
- Mälardalen University
Atrial Fibrillation (AF), 3D Printing
3D Printing Technology For Planning Left Atrial Appendage Occlusion
Atrial fibrillation is the most common cardiac arrhythmia, affecting 8.5% of the general population in Hong Kong. Systemic embolization, and particularly stroke, is the most frequent major complication of atrial fibrillation.
- Conditions
- Atrial Fibrillation (AF), 3D Printing, Cost Benefit Analysis
- Trial name
- NCT07483008
- Testing
- 3D-printed models of the left atrial appendage, Standard preoperative planning
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- Chinese University of Hong Kong
Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm
Fast-Track Protocol for Endovascular Aneurysm Repair (EVAR) of Infrarenal Abdominal Aortic Aneurysms
The study aims to evaluate the clinical and economic efficacy of a "Fast-Track" protocol for the elective endovascular treatment (EVAR) of infrarenal abdominal aortic aneurysms (AAA).
- Conditions
- Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Iliac Aneurysm
- Trial name
- NCT07431047
- Volunteers
- 50 people
- Sponsor
- University of Bologna
Chest Pain, Myocardial Infarction
The Supplementary Role of Non-invasive Imaging to Routine Clinical Practice in Suspected Non-ST-elevation Myocardial Infarction
Approximately half of patients with acute chest pain, a very common reason for emergency department visits worldwide, have a cardiac cause.
- Conditions
- Chest Pain, Myocardial Infarction, Acute Coronary Syndrome, Coronary Artery Disease
- Trial name
- CARMENTA (NCT01559467)
- Testing
- Cardiovascular Magnetic Resonance Imaging, Computed Tomography Angiography
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Maastricht University Medical Center
Osteoarthritis,Knee
Costs and Benefits of ConforMIS iTotal® Knee Replacement System Versus Standard Total Knee
The purpose of this study is to evaluate the costs and benefits of the ConforMIS iTotal® total knee replacement system versus standard total knee arthroplasty.
- Trial name
- NCT01899417
- Testing
- ConforMIS iTotal® Knee Replacement
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Restor3D
Osteoporotic Fracture
Effectiveness or Orthopedic Intervention in Osteoporosis Management After a Fracture of the Hip With Cost-Benefit Analysis
Patients who present with fragility fractures are consistently under-evaluated and under-treated for underlying osteoporosis. This point of care represents a lost opportunity to prevent future fractures.
- Trial name
- NCT02239523
- Testing
- Letter Group, Intervention Group
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Shaare Zedek Medical Center
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Parenting, Parent-Child Relations
Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth
The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system.
- Conditions
- Parenting, Parent-Child Relations, Child Behavior, Child Maltreatment
- Trial name
- NCT06109766
- Testing
- Promoting First Relationships
- Where
- United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pregnancy Complications Nos, Labor/Delivery Problems Nos
Early Postnatal Discharge in a French Perinatal Network
The purpose of this "before-after" study is to determine the effectiveness of a multidimensional intervention to increase the rate for early discharge of low-risk mothers and the healthy newborn in a perinatal network.
- Conditions
- Pregnancy Complications Nos, Labor/Delivery Problems Nos, Vitality; Newborn
- Trial name
- SORPRISE (NCT02298569)
- Testing
- multi-pronged program to improve early postpartum discharge
- Where
- 5 sites in France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Grenoble
Chronic Disease
Biomarker Cost-Benefit Analysis of EFNEP
The goal of this integrated project is to assess whether EFNEP is a cost-effective nutrition education intervention that generates sustained improvement in chronic disease biomarkers.
- Trial name
- NCT05558085
- Testing
- Expanded Food and Nutrition Education Program (EFNEP)
- Where
- 4 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Postoperative Complications, Cost-Benefit Analysis
Advanced Recovery Room Care II - Improved Recovery After Surgery
Moderate-risk surgical patients have a very high incidence of early serious postoperative complications (approximately 50% at Royal Adelaide Hospital, RAH).
- Trial name
- ARRCII (NCT04769518)
- Testing
- Advanced Recovery Room Care (ARRC)
- Where
- Australia
- Volunteers
- 857 people
- Sponsor
- University of Adelaide
HIV
Gathering Records to Evaluate Antiretroviral Treatment-South Africa
To achieve global goals for the treatment of HIV, most high-prevalence countries are experimenting with and scaling up differentiated service delivery models (DSD).
- Trial name
- GREAT (NCT04149782)
- Testing
- Routine medical record data collection
- Where
- South Africa
- Volunteers
- 7,000,000 people
- Sponsor
- Boston University
Coronary Artery Disease, Cardiac Rehabilitation
Electronic Cardiac Rehabilitation (eCardiacRehab) Feasibility Study
In Norway, more than 11,000 patients undergo percutaneous coronary intervention (PCI) annually. However, a very recent study utilizing registry data show a national average of cardiac rehabilitation (CR) participation of only…
- Conditions
- Coronary Artery Disease, Cardiac Rehabilitation, Ethics, Continuity of Patient Care
- Trial name
- eCardiacRehab (NCT06759805)
- Testing
- eCardiacRehab
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Haukeland University Hospital
Joint Disease
A Comparison Between Signature Total Knee Arthroplasty (TKA) to Conventional TKA and Computer Assisted TKA
This is a prospective, randomised clinical outcomes study comparing the Signature Personalised Patient Care, Conventional Total Knee Arthroplasty and Computer Assisted Navigation, using Vanguard Knee System.
- Trial name
- NCT01145157
- Testing
- Signature Knee Guide, Conventional Instrumentation, Computer Assisted Navigation
- Where
- Australia
- Volunteers
- 150 people
- Sponsor
- Zimmer Biomet
User Experience
Desktop Versus Mobile Data Collection in Clinical Trial
Paper-based data collection for prospective clinical trials is associated with a poor quality of data collection. This typically involves missing or wrong data entry or a low recruitment rate, mainly due to the cumbersome and…
- Trial name
- NCT01473238
- Testing
- Evaluation form
- Where
- 2 sites in Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Lymphoma, Non-Hodgkin, Granulocyte Colony-Stimulating Factor
Cost-Effectiveness Study of PEG-rhG-CSF in Prophylactic Treatment of Neutropenia After Chemotherapy in Lymphoma
This is a pharmacoeconomic research to explore the cost-effectiveness of PEG-rhG-CSF and rhG-CSF in prophylactic treatment of neutropenia in lymphoma patients. It should provide more scientific basis for clinical decision-making.
- Conditions
- Lymphoma, Non-Hodgkin, Granulocyte Colony-Stimulating Factor, Cost-Benefit Analysis
- Trial name
- NCT04083079
- Testing
- PEG-rhG-CSF, rhG-CSF
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Ruijin Hospital
Surgical Site Infection
Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients
Despite the use of prophylactic systemic antibiotics and improved surgical technique, surgical site infections remain a serious concern.
- Trial name
- NCT01566422
- Testing
- Vancomycin powder
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Neoplasms
Pharmacogenomic and Pharmacokinetic Safety and Cost-saving Analysis in Patients Treated With Fluoropyrimidines
The primary purpose of this study is to prospectively determine whether capecitabine and 5-FU-induced toxicity is preventable by dose reduction prior to start of the first administration in patients heterozygous or homozygous…
- Trial name
- NCT00838370
- Testing
- Capecitabine, 5-fluorouracil
- Where
- 3 sites in Netherlands
- Volunteers
- 22 people
- Sponsor
- The Netherlands Cancer Institute