Clinical trials: Cost-Effectiveness
Dental Caries
Occlusal-proximal ART Restorations in Primary Molars Using 2 Different Kinds of GIC
The aim of this research is to investigate the survival rate and cost effectiveness of two brands of GIC as occlusal-proximal ART restorations. Also the survival rate of the tooth will be investigated.
- Trial name
- NCT02267720
- Testing
- Occlusal-proximal ART restorations - Ketac Molar, Occlusal-proximal ART restorations - Vitro Molar
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Obesity
Evaluation of an Enhanced Delivery Model for Go NAPSACC
This study will compare the effectiveness and cost of Basic and Enhanced delivery models for Go NAPSACC on child care centers' use of evidence-based nutrition and physical activity practices.
- Trial name
- NCT03938103
- Testing
- Enhanced Go NAPSACC, Basic Go NAPSACC
- Where
- 2 sites in United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Health Systems, Electronic Community Health Information Systems
Digital Data Linkage and Scheduling to Track Pregnancy With or Without Community Data Use to Increase Antenatal Clinic Uptake in Western Kenya.
The investigators propose to increase ANC uptake through a health systems strengthening approach that links digital data platforms and trains community Work Improvement Teams (WITs) to use these data to identify problems and come…
- Conditions
- Health Systems, Electronic Community Health Information Systems, Antenatal Clinic Uptake, Pregnancy
- Trial name
- C-it-DU-it (NCT05929586)
- Testing
- The combined "C-it DU-it" intervention: community data use for ANC
- Where
- Kenya
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Functional Status, Frailty
Protocol for Inpatient Nursing Frailty Assessment (INFA)
Background: Frailty confers greater risks of negative health outcomes in hospitalised older adults. To improve care for this vulnerable population, Comprehensive Geriatric Assessment (CGA) is recommended for frail older persons.
- Trial name
- NCT06469723
- Testing
- INFA Program
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Edentulous Alveolar Ridge
Effectiveness of Removable Prosthesis Retained by 4 Implant-supported Locator-Attachments
1. Hypothesis/Specific aims The aim of the present study proposal is to validate an implant treatment concept in the edentulous upper maxilla using four implants-supported locators abutments to retain removable prosthesis.
- Trial name
- LOC (NCT02380404)
- Testing
- Implants-supported locators placement
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Older Adults
Self-administered Dual-task Training for Reducing Falls Among the Older Adults
Evidence supports that dual-task training reduces fall risk among older adults. However, the current framework for preventive care for fall prevention in Hong Kong does not include formal cognitive training, while little to no…
- Trial name
- sDTT (NCT05533333)
- Testing
- Falls prevention exercises
- Where
- Hong Kong
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Childhood Severe Illness, Pneumonia
Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in Kenya and Senegal
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Childhood Severe Illness, Pneumonia, Primary Health Care, Hypoxia
- Trial name
- TIMCI (NCT05065320)
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 51,590 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Weight Loss
Cost-Effectiveness of Weight Loss Prevention in Nursing Homes: A Controlled Trial
Low oral food and fluid intake and unintentional weight loss are common problems among long-stay nursing home (NH) residents and are associated with adverse, costly clinical outcomes.
- Trial name
- NCT02567513
- Testing
- Supplement Intervention, Snack Intervention
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Primary Infertility, Secondary Infertility
Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF
The purpose of this study to evaluate a low cost minimal stimulation protocol combined with Intravaginal Culturing, to make IVF affordable and available across the large infertile/subfertile population
- Conditions
- Primary Infertility, Secondary Infertility, Low Responders, Mild to Moderate Male Factor Infertility
- Trial name
- MSP-INVO IVF (NCT01058252)
- Testing
- INVOCell, Letrozole 2.5 mg, recFSH 75 IU, STEP-3: LH Suppression & Monitoring, STEP-4: HCG Timing
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galaxy Pharma (Pvt) Limited
Cost Effectiveness
Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant
The aim of the present study is determine the cost-effectiveness, clinical-effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted…
- Trial name
- NCT04603573
- Testing
- fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride ), Resin based fissure sealant (3M Clinpro sealant )
- Where
- Egypt
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malaria Infection, Malaria Vaccines
Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad
This is a two-arm, cluster-randomised, phase IV trial conducted in Chad to assess the protective efficacy and impact in real-life conditions of a new strategy for administering the R21/MM malaria vaccine, synchronized within a…
- Trial name
- COSAV-R21 (NCT07038837)
- Testing
- "Synchronised" arm (intervention)
- Where
- Chad
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Epicentre
Dengue Fever
Bridging Economics and Public Trust: A Study of Dengue Vaccine Cost-effectiveness and Acceptance in Thais Visiting Hospital
Study 1: Cost-effectiveness of TAK-003 Dengue Vaccination in Thailand This study aims to evaluate the cost-effectiveness of introducing the live-attenuated tetravalent dengue vaccine (TAK-003) into Thailand's national…
- Trial name
- NCT07759596
- Testing
- Objective 1- economic evaluation of Thai children with dengue vaccine
- Where
- Thailand
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Caregiver Burden, Financial Stress
CONFIDENCE Financial Education for Caregivers
The purpose of this study is to determine how feasible it is to deliver an online course to reduce out-of-pocket costs of caregiving and reduce financial stress among Latino family caregivers to a family member living with…
- Conditions
- Caregiver Burden, Financial Stress, Dementia, Alzheimer Disease
- Trial name
- CONFIDENCE (NCT05292248)
- Testing
- Confidently Navigating Financial Decisions and Enhancing Financial Wellbeing in Dementia Caregiving
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Breast Cancer Female, Colorectal Cancer
Increasing Colorectal and Breast Cancer Screening in Women
This study compares the efficacy (adherence and stage) of four interventions to promote colorectal (CRC) and breast cancer (BC) screenings among women ages 50 to 75. They are: 1. usual care; 2.
- Trial name
- COBRA (NCT03279198)
- Testing
- TIWeb, CSC, UC
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- Indiana University
Malaria,Falciparum
The Impact RTS,S/AS01 Vaccine in School Aged Children RTS,S/AS01 Malaria Vaccine in School Aged Children
Across sub-Saharan Africa, school-age children bear an under-appreciated burden of malaria. An estimated 200 million school-age children are at risk of malaria and in many areas prevalence of infection exceeds 50%.
- Trial name
- NCT06424002
- Testing
- Mosquirixs, artemether-lumefantrine
- Volunteers
- 5,400 people, healthy volunteers welcome
- Sponsor
- Kamuzu University of Health Sciences
Pityriasis Versicolor
The Comparative Assessment of Mycological Efficacy, Safety, Recurrence, and Cost-effectiveness of Selenium Sulfide 1.8% Shampoo Versus Ketoconazole 2% Shampoo in Pityriasis Versicolor: a Double-blind Randomized Controlled Trial
There are several topical treatment for Pityriasis Versicolor including ketoconazole and selenium sulfide. Ketoconazole is a broad spectrum anti-fungal drug from imidazole group that has been reported to be effective in PV.
- Trial name
- NCT04007237
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Stroke
Monitoring Arm Recovery After Stroke (MARS)
People who have a stroke often find it hard to do the things they did before. This can be caused by problems with arm movement. One in five people do not get any arm movement back after a stroke.
- Trial name
- MARS (NCT07016295)
- Testing
- Biomechanical analysis of arm movement, Pose estimation of arm movement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Sexually Transmitted Infections, HIV
Multimedia WORTH With Black Drug-Involved Women on Probation
The proposed study is a randomized controlled trial (RCT) that will rigorously evaluate the effectiveness and cost-effectiveness of delivering a multimedia evidence-based intervention (WORTH) and streamlined HIV testing to…
- Conditions
- Sexually Transmitted Infections, HIV, Gonorrhea, Trichomonas
- Trial name
- E-WORTH (NCT02391233)
- Testing
- E-WORTH, Streamlined HIV Testing
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Columbia University
Smoking
Smoking Cessation in a Dentistry Setting
Aim: to assess relative effectiveness of a high and a low intensity intervention for smoking cessation support in a dental clinic setting.
- Trial name
- NCT00670514
- Testing
- Nix Individual, Fimpa dig fri
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Pain
Evaluating VR Therapy Using Cold Pressor Test
This study is testing whether or not low-cost, virtual reality (VR) headsets for mobile phones can be used as a potential distractor from pain and thus would have clinical applications as a low-cost, non-pharmaceutical method to…
- Trial name
- NCT03268863
- Testing
- Virtual Reality, Cold Pressor
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Janet Vittone