Clinical trials: Cough Severity
Influenza, Common Cold
Pomegranate Products for Prevention of Common Cold
Pomegranate has a long history of use in folk medicine. There is vast data on the health benefits of pomegranate fruit and juice.
- Conditions
- Influenza, Common Cold, Cough, Headache
- Trial name
- NCT00617318
- Testing
- Pomegranate
- Where
- United States
- Volunteers
- 461 people, healthy volunteers welcome
- Sponsor
- Texas Heart Institute
Bordetella Pertussis, Whooping Cough
Impact of Bacterial Expression and Immune Response in the Severity of Pertussis
The resurgence of pertussis is associated with an evolutionary mechanism under the pressure of current acellular vaccines, with a possible impact on vaccine effectiveness and disease expression.
- Trial name
- PERT-SEVEREII (NCT05897879)
- Testing
- Nasopharyngeal swab, Blood samples
- Where
- 14 sites in France
- Volunteers
- 210 people
- Sponsor
- Institut Pasteur
Asthma, Cough Variant Asthma
Optimal Type of Inhaler in Cough Variant- or Cough Predominant Asthma
Asthma management is based on inhaled therapy, mainly on inhaled glucocorticosteroids (ICS). The efficacy of inhaled therapy depends on type of inhaler and proper inhalation skills.
- Trial name
- NCT04203472
- Testing
- Budesonid or budesonide/fomoterol administered by DPI, Budesonid or budesonide/fomoterol administered by MDI
- Where
- Poland
- Volunteers
- 22 people
- Sponsor
- Medical University of Warsaw
Pericarditis
Effects of Pulmonary Rehabilitation Versus Standard Care in Patients With Pericarditis
Pericarditis is associated with symptoms such as chest pain, dyspnea, fatigue, cough, and anxiety, which can significantly impair functional capacity and quality of life.
- Trial name
- NCT07716696
- Testing
- Pulmonary Rehabilitation, Standard Care
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
Chronic Cough (CC), Healthy Adult Participants
Impact of Refractory Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise
Chronic cough is a common and debilitating condition that affects up to 10% of the global population. The health impact of chronic cough is multifaceted and manifests both physical and psychological symptoms including syncope…
- Trial name
- NCT06766175
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Post COVID-19
Value of Montelukast as a Potential Treatment of Post COVID-19 Persistent Cough
As of September 2020, the COVID-19 pandemic has affected millions of people in 196 countries and left hundreds of thousands dead.
- Trial name
- NCT05447039
- Testing
- Montelukast Sodium Tablets
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Assiut University
Pulmonary Fibrosis
A Study in People With Pulmonary Fibrosis to Monitor Cough With a Wearable Device
This study is open to adults aged 18 years and older who have pulmonary fibrosis with or without a known cause (or other forms of pulmonary fibrosis).
- Trial name
- NCT05670587
- Testing
- A wearable cough monitoring device, the Strados Labs RESPᵀᴹ sensor, with an accompanying mobile application (App) for data collection
- Where
- 13 sites in United States, Belgium and 2 more
- Volunteers
- 53 people
- Sponsor
- Boehringer Ingelheim
Hemorrhoid, Cough
Cough and Hemorrhoids
The aim of the study is to investigate the relationship between hemorrhoids and cough by assessing the symptoms, duration, and severity of cough in patients who will present to the general surgery outpatient clinic of Muğla…
- Conditions
- Hemorrhoid, Cough, Cough Duration, Cough Frequency
- Trial name
- NCT06878209
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Muğla Sıtkı Koçman University
Airway Complications, Postoperative Sore Throat
Effect of Cuff Pressure Assessment Methods on Postoperative Complications in Breast Surgery
Endotracheal intubation is a standard procedure used to secure the airway during general anesthesia. A key component of the breathing tube is the "cuff," a balloon-like device that is inflated to seal the airway and prevent…
- Conditions
- Airway Complications, Postoperative Sore Throat, Hoarseness, Dysphagia
- Trial name
- NCT07341646
- Testing
- Continuous Cuff Pressure Indicator, Manual Cuff Pressure Manometer, Minimal Occlusive Volume Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Izmir Katip Celebi University
Stress Urinary Incontinence (SUI)
Single Incision Suburethral Sling at Time of Robotic Sacrocolpopexy
This study was designed to evaluate urinary function before and one year after single incision sling placement at the time of robotic sacrocolpopexy.
- Trial name
- NCT01982188
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Atlantic Health System
Upper Respiratory Infections
Warming Sensation Intensity and Acceptability of the Flavour, Local Tolerability of Paracetamol 500 mg + Phenylephrine 10mg + Guaifenesin 200 mg Syrup in Patients Suffering a Upper Respiratory Tract Infection (URTI)
This is an open label, in-use study to assess the warming sensation, acceptability and local tolerability of paracetamol 500 mg + phenylephrine 10mg + Guaifenesin 200 mg syrup, given as a single dose in subjects suffering from…
- Trial name
- NCT01576809
- Testing
- IFF flavor 316 282, Paracetamol , Phenylephrine, Guaifenesin
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Novartis
Chronic Cough, OSA
Sham CPAP vs. Straight CPAP for Chronic Cough
Chronic cough is an important clinical problem in primary care and sub-specialty practice. Besides the distress experienced by patients with chronic cough, significant healthcare resources are expended to understand the role of…
- Trial name
- NCT03172130
- Testing
- Straight CPAP
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Krishna M. Sundar
Asthma, Exercise-Induced, Asthma
Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma
The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments.
- Trial name
- NCT04302610
- Testing
- Heat and Moisture Exchange mask (ColdAvenger® expedition balaclava, USA,
- Volunteers
- 26 people
- Sponsor
- University of Kent
Respiratory Sounds
Assessment of Cough and Wheeze With Breath Sound Documenting Device
The study goal is to create a database of respiratory sounds recordings, to evaluate and validate the WIM technology and to evaluate the efficacy of a specific treatment by comparing the severity of the respiratory symptoms…
- Trial name
- NCT00711399
- Testing
- PulmoTrack® 2010 with WIM-PC™ and WIM-CC™ Technologies
- Where
- Israel
- Volunteers
- 55 people
- Sponsor
- Carmel Medical Center
Idiopathic Pulmonary Fibrosis, Cough
Efficacy and Safety of ME-015 (Suplatast Tosilate) in Cough Related to Idiopathic Pulmonary Fibrosis (COSMIC-IPF)
Orally administered ME-015 (Suplatast Tosilate) has been available on the market as a prescription drug for allergy-related conditions in Japan since 1995 with a good safety and tolerability profile.
- Conditions
- Idiopathic Pulmonary Fibrosis, Cough, IPF, Fibrotic Lung Disease
- Trial name
- COSMIC-IPF (NCT05983471)
- Testing
- ME-015 (Suplatast Tosilate)
- Where
- 6 sites in India
- Volunteers
- 40 people
- Sponsor
- Melius Pharma AB
Bronchiectasis
Sputum Clearance Effects of Hypertonic Saline in Non-cystic Fibrosis Bronchiectasis
This study aims to analyze whether the hypertonic saline nebulization enhances sputum clearance effects, reduces the impact on cough severity and their level of safety and tolerability in a population with non-cystic fibrosis…
- Trial name
- NCT02392663
- Testing
- Hypertonic saline solution, Hyaneb solution, Isotonic saline solution
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Hospital Clinic of Barcelona
Thyroidectomy, Colon Surgery
Effect of the Coughing Technique During Subcutaneous Heparin Injection
Objective: to examine the effect of the medium intensity coughing technique during subcutaneous low molecular weight heparin injection on pain severity and individual satisfaction in general surgery patients.
- Conditions
- Thyroidectomy, Colon Surgery, Cholecystectomy, Inguinal Hernia
- Trial name
- NCT05681338
- Testing
- the medium intensity coughing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uludag University
Lung Diseases, Interstitial
Correlation Between Changes in Lung Function and Changes in Cough and Dyspnoea in Nintedanib-treated Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) Patients
The aim of this study is to identify correlations between change from the baseline at Month 24 in Forced Vital Capacity (FVC) (% predicted and mL) and change from the baseline at Month 24 in cough or dyspnoea scores [points] as…
- Trial name
- NCT05503030
- Testing
- Nintedanib
- Where
- 20 sites in Greece
- Volunteers
- 88 people
- Sponsor
- Boehringer Ingelheim
Cough
Concentrations of Remifentanil for Extubation
Condition of the State: (terminated, recruiting, etc.) Terminated Study Design: Main Objective: Compare the frequency and intensity of coughing at the time of extubation with two infusions of remifentanil that predict a plasma…
- Trial name
- REMEX (NCT02711904)
- Testing
- Extubation U, Extubation T
- Where
- Colombia
- Volunteers
- 110 people
- Sponsor
- Seganest
Asthma, COPD
Sputum and Plasma Levels of Nociceptin and Substance P in Patients With Asthma, COPD and Chronic Cough
The aims of this study are to investigate the association between sputum and plasma levels of nociceptin and substance P with cough severity and airway hyperreactivity in patients with asthma, COPD and chronic cough.
- Conditions
- Asthma, COPD, Cough
- Trial name
- NCT00173225
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital