Clinical trials: Covid-19 Patients
Covid19
Micronized and Ultramicronized Palmitoylethanolamide in COVID-19 Patients
SARS-CoV-2 infection is a condition characterized by excessive leukocyte infiltration, massive release of chemokines, proteases and cytokines, the so-called "cytokine storm", which promote the inflammatory process and contribute…
- Trial name
- NCT04568876
- Testing
- Micronized and ultra-micronized Palmitoylethanolamide (mPEA and umPEA, 300mg + 600mg) oral suspension, Standard Therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Epitech Group SpA
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Comparison of Non-invasive Oxygenation Strategies in Patients Admitted for Covid-19 Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome (ARDS) is the main clinical presentation of SARS-CoV-2 (Covid-19) infected patients admitted in Intensive Care Unit (ICU).
- Trial name
- SONIC-19 (NCT04725084)
- Testing
- Use of High Flow Nasal Cannula alone, Use of Non-invasive Ventilation, Use of Continuous Positive Airway Pressure
- Where
- 4 sites in France
- Volunteers
- 355 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
COVID - 19
Open Label Study to Compare Efficacy, Safety and Tolerability of Hydroxychloroquine Combined With Azithromycin Compared to Hydroxychloroquine Combined With Camostat Mesylate and to "no Treatment" in SARS CoV 2 Virus
Patients with COVID-19 which are 60 years old or above or with comorbidities are at risk of deteriorating and developing severe illness.
- Trial name
- COSTA (NCT04355052)
- Testing
- hydroxychloroquine in combination with camostat mesylate, Hydroxychloroquine in combination of Azithromycin
- Where
- 2 sites in Israel
- Volunteers
- 250 people
- Sponsor
- Sheba Medical Center
COVID, SARS-CoV-2
European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO
In the last 10 years, severe acute respiratory infection (SARI) was responsible of multiple outbreaks putting a strain on the public health worldwide.
- Conditions
- COVID, SARS-CoV-2, ARDS, Human, Refractory Hypoxemia
- Trial name
- EuroECMO-COVID (NCT04366921)
- Where
- 97 sites in Austria, Belgium and 17 more
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Covid19, Smoking
The Effects of Smoking on Mortality in Patients With Acute Respiratory Syndrome Coronavirus 2 Infection
This is a retrospective single centered study that was done in the ICU on patients with Covid-19 between 16th of March -16th of May in 2020 Retrospective records will be examined by examining the electronic data files of the…
- Trial name
- NCT04874363
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Covid19, Cytokine Storm
Menstrual Blood Stem Cells in Severe Covid-19
In this randomized controlled trial (RCT), severe cases of COVID-19 infection will be treated with secretome of menstrual blood stem cells.
- Trial name
- NCT05019287
- Testing
- Allogeneic human menstrual blood stem cells secretome, Intravenous saline injection
- Where
- Iran
- Volunteers
- 29 people
- Sponsor
- Avicenna Research Institute
Coronavirus Infection, Diabetes Mellitus, Type 2
Canakinumab in Patients With COVID-19 and Type 2 Diabetes
The purpose of this study is to evaluate whether Canakinumab has beneficial effects on patients with Type 2 diabetes mellitus and coronavirus disease 19 (COVID19).
- Trial name
- CanCovDia (NCT04510493)
- Testing
- Canakinumab
- Where
- 9 sites in Switzerland
- Volunteers
- 116 people
- Sponsor
- University Hospital, Basel, Switzerland
Alzheimer Disease, Telerehabilitation
Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease
Our aim has been determined to investigate the effect of physical exercise alone and in combination with cognitive exercise, on cognitive, physical function and quality of life in individuals with Alzheimer's Disease during the…
- Conditions
- Alzheimer Disease, Telerehabilitation, Online Physical Exercise, Computerized Cognitive Stimulation
- Trial name
- NCT04842734
- Testing
- Physical exercise, Physical exercise and computerized cognitive training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yeditepe University
COVID-19
A Study Evaluating the Efficacy and Safety of CKD-314 (Nafabelltan) in Hospitalized Adult Patients Diagnosed With COVID-19 Pneumonia
The primary objective of this study is to evaluate the efficacy of CKD-314 (Nafabelltan) compared to standard of care (SOC), with respect to clinical status assessed by a 7-point ordinal scale in hospitalized adult patients…
- Trial name
- NCT04623021
- Testing
- Nafamostat Mesilate
- Where
- 11 sites in Russia
- Volunteers
- 104 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Corona Virus Infection, Hypoxic Respiratory Failure
Timed Awake Prone and Repositioning for Patients With Covid-19-induced Hypoxic Respiratory Failure.
Awake prone positioning has been reported to improve oxygenation for patients with COVID-19. Awake timed and repositioning is a novel method to improve patients' compliance and prolong the prone time.
- Trial name
- NCT05689216
- Testing
- Awake timed prone and repositioning
- Where
- 3 sites in China
- Volunteers
- 286 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain Management
Online Pain Management Programmes During the Covid-19 Pandemic
A focus groups study facilitating an open discussion regarding the experience of being assessed for an online Pain Management Programme (OPMP) during the Covid-19 Pandemic.
- Trial name
- NCT07838363
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Walton Centre NHS Foundation Trust
Coronavirus Infections
Bevacizumab in Severe or Critical Patients With COVID-19 Pneumonia
The novel identified coronavirus (SARS-CoV-2) in 2019 causes an nationwide outbreak as well as public health crisis in China, and expands globally.
- Trial name
- BEST-CP (NCT04275414)
- Testing
- Bevacizumab Injection
- Where
- 3 sites in China, Italy
- Volunteers
- 27 people
- Sponsor
- Qilu Hospital of Shandong University
COVID, COVID-19
Subcutaneous Sarilumab vs Placebo in Hospitalized Patients With Respiratory Distress Caused by COVID 19
Studying the efficacy of IL-6 inhibition utilizing single or double dose subcutaneous administration of Sarilumab in patients with severe respiratory distress caused by COVID19 regarding improvement in oxygen demands and other…
- Conditions
- COVID, COVID-19, Corona Virus Infection
- Trial name
- NCT07196306
- Testing
- Sarilumab 200 MG/1.14 ML Subcutaneous Solution
- Where
- 3 sites in United States
- Sponsor
- BayCare Health System
Critical Illness, Covid19
Body Composition Study in Critically Ill Patients-Extended to COVID-19
Muscle loss (ultrasound quadricep muscle) and muscle strength (handgrip and knee extension strength) will be compared between COVID-19 and non COVID-19 critically ill patients.
- Conditions
- Critical Illness, Covid19, Muscle Atrophy, Muscle Strength
- Trial name
- COVID-MUSCLE (NCT04849624)
- Testing
- No Intervention
- Where
- Malaysia
- Volunteers
- 59 people
- Sponsor
- University of Malaya
Sars-CoV2, Covid-19
Cardiac Arrest Incidence and Outcome Among Patients With COVID-19 in French ICUs
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the novel coronavirus disease 2019 (COVID-19) pandemic.
- Trial name
- ACICOVID (NCT04373759)
- Testing
- Cardiopulmonary resuscitation, Modified Rankin score
- Where
- 36 sites in France, Martinique
- Volunteers
- 186 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Post-acute COVID-19 Syndrome
The Effect of Micellized Food Supplements on Health-related Quality of Life in Patients With Post-acute COVID-19 Syndrome.
Food supplements like curcumin and boswellia serrata have been used traditionally for anti-inflammatory purposes. A well-known problem of these substances in their natural form is the low bioavailability.
- Trial name
- NCT05150782
- Testing
- Curcumin/Boswellia Serrata/Ascorbic acid mixture
- Volunteers
- 32 people
- Sponsor
- PhysioMetrics
COVID-19
Exploring the Experiences, Expectations and Preferences of Patients With the UHS COVID-19 Follow-up Clinic
People who are older, those who had underlying other health conditions and people living in poorer communities are at increased risk of complications and worse outcome from COVID-19.
- Trial name
- NCT05799482
- Testing
- Qualitative Interview
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
COVID-19
Minimal Invasive Autopsies to Investigate Changes in Deceased COVID-19 Patients
Rationale In a very short time corona virus disease 2019 (COVID-19) has become a pandemic with high morbidity and mortality. The main cause of death is respiratory failure including acute respiratory distress syndrome, however…
- Trial name
- MIA-COVID-19 (NCT04366882)
- Testing
- CT-scan with minimal invasive autopsy
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Jessa Hospital
Corona Virus Infection, Covid19
Clinical Study Designed to Evaluate the Effect of CimetrA in Patients Diagnosed With COVID-19
A preparation of CimertrA, comprising Artemisinin, Curcumin, and Boswellia, and Vitamin C in a nanoparticular formulation, is proposed as a treatment for the disease associated with the novel coronavirus SARS-CoV-2.
- Conditions
- Corona Virus Infection, Covid19, SARS-CoV Infection
- Trial name
- CimetrA (NCT04802382)
- Testing
- Confirm SARS-CoV-2 infection, Physical Examination, Vital Signs
- Where
- 2 sites in Israel
- Volunteers
- 252 people
- Sponsor
- MGC Pharmaceuticals d.o.o
Covid19, Virus-HIV
Prevalence of COVID-19 Infection in a Cohort of Patients Infected by the HIV and Patients Taking PrEP
The purpose of the study is to assess seroprevalence of COVID-19 infection in a cohort of HIV + patients and in a cohort of patients taking PrEP by emtricitabine / tenofovir.
- Trial name
- NCT04575545
- Testing
- Serology test for COVID-19
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Hôpital Européen Marseille
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