Clinical trials: Covid19- Coronavirus- Sars-cov-2
Sars-CoV2, Osteoporosis
Psychological Impact of Quarantine in Osteoporosis Patient During COVID-19 Outbreak
In the context of quarantine with COVID-19, we wish to study the experience and psychological impact in adult patients living with osteoporosis.
- Trial name
- OsPsyCOVID (NCT04351633)
- Testing
- questionnaire assesment
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Lille
Infection, Coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2
Host-pathogen Interactions During SARS-CoV-2 Infection
The new Severe acute respiratory syndrome coronavirus (SARS-CoV-2) named coronavirus disease 2019 (COVID-19) is currently responsible for a pandemic spread of febrile respiratory infections, responsible for a veritable global…
- Trial name
- HPI-COVID-19 (NCT04376476)
- Testing
- Blood sample, Low or upper respiratory tract sample, Stool collection or fecal swab
- Where
- 12 sites in France
- Volunteers
- 140 people
- Sponsor
- Hospices Civils de Lyon
SARS-CoV-2, COVID-19
A Study of the Effectiveness of Moderna COVID-19 Vaccine
This is an observational cohort study to evaluate real-world vaccine effectiveness and durability of Moderna COVID-19 vaccine among a diverse population at Kaiser Permanente Southern California (KPSC).
- Trial name
- NCT05933304
- Where
- United States
- Volunteers
- 927,004 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Gut Microbiome, Gastrointestinal Microbiome
A Study to Explore the Role of Gut Flora in COVID-19 Infection
This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, COVID, COVID-19
- Trial name
- NCT04359836
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Microbiome, Vaccine
Gut Microbiota, the Potential Key to Modulating Humoral Immunogenicity of New Platform COVID-19 Vaccines
Vaccination is the best way to mitigate the coronavirus disease 2019 (COVID-19) pandemic, but the vaccine immunogenicity may be quite variable from person to person.
- Conditions
- Microbiome, Vaccine, Covid-19, SARS-CoV-2
- Trial name
- NCT05150834
- Testing
- This is observational study
- Where
- South Korea
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Long COVID
Prospective, Open-label Study of Seraph 100 in Patients With Prolonged COVID (PC)
This study will use a prospective, open, single-arm design, in which a group of 100 patients with a diagnosis of prolonged COVID, previously selected according to inclusion and exclusion criteria, and who have undergone informed…
- Trial name
- NCT06637800
- Testing
- Seraph® 100 Microbind® Affinity Blood Filter (Seraph 100)
- Where
- Mexico
- Sponsor
- ExThera Medical Corporation
Covid19
Impact of Maternal COVID-19 Disease on Breast Milk and Infant Health
prospective multicenter study The main aim is to study the impact of maternal COVID-19 on breast milk immune, microbiological, and metabolic profile and infant growth and development
- Trial name
- MilkCorona (NCT04768244)
- Testing
- maternal SARS-CoV-2 infection
- Where
- 2 sites in Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute of Agrochemistry and Food Technology, National Research Council
Coronavirus Disease 2019 (COVID-19)
Pharmacokinetics, Safety, and Tolerability of CSL760, an Intravenous Anti-SARS-CoV-2 Hyperimmune Globulin, in Healthy Adult Subjects
CSL760 is a human hyperimmune product of the purified gamma immunoglobulin (IgG) fraction of human plasma containing polyvalent neutralizing antibodies to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2).
- Trial name
- NCT04638634
- Testing
- CSL760
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CSL Behring
SARS-CoV-2
COVID-19 Treatment Using Methylene Blue and Photodynamic Therapy
According to the epidemiological situation worldwide and the number of vaccinations made, there is little success in the fight against COVID-19.
- Trial name
- NCT04933864
- Testing
- Methylene Blue and Photodynamic Therapy
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Quality of Life, Long-term Outcomes
Quality of Life and Patient-centered Outcomes After ICU Admission for COVID-19
Patients suffering from pneumonia due to SARS-CoV-2 infection, after admission to the Intensive Care Unit (ICU), are susceptible to development of various functional sequelae, increased risk of chronic diseases, increased…
- Conditions
- Quality of Life, Long-term Outcomes, Coronavirus Infection, Morality
- Trial name
- NCT04416464
- Testing
- COVID-19 Pneumonia
- Where
- 3 sites in Portugal
- Volunteers
- 280 people
- Sponsor
- Universidade do Porto
Long COVID, Long COVID-19
AT1001 for the Treatment of Long COVID
The primary objective of this study is to evaluate the safety and efficacy of Larazotide (AT1001) versus placebo in children and adults 7 to ≤50 years of age who present with symptoms of Long COVID in the presence of SARS-CoV-2…
- Conditions
- Long COVID, Long COVID-19, Post Acute COVID-19 Syndrome, Post Acute Sequelae of COVID-19
- Trial name
- NCT05747534
- Testing
- Larazotide Acetate
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Massachusetts General Hospital
COVID-19
Development and Validation of a Prediction Model for the Transition From Mild to Moderate Form of COVID-19, Using Data From Chest CT
Only 5% of patients infected with COVID-19 develop severe or critical Coronavirus disease 2019 (COVID-19) and there is no reliable risk stratification tool for non-severe COVID-19 patients at admission.
- Trial name
- PREDICTCovid19 (NCT04481620)
- Where
- 7 sites in France
- Volunteers
- 1,329 people
- Sponsor
- University Hospital, Bordeaux
Long COVID
Clinical and Biological Characterization of Post COVID-19 Syndrome
The goal of this observational study is to describe the symptoms that persist for more than 12 weeks after the acute episode in participants who had COVID-19, and compare the functional, socioeconomic and occupational effects…
- Trial name
- NCT05735782
- Testing
- Clinical, mental health and psychosocial profile of Post-COVID-19 syndrome, Diagnostic performance of echocardiographic and biological markers in Post-COVID-19 syndrome
- Where
- Argentina
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Arturo Jauretche National University
Influenza, COVID-19
Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination
Background: Influenza (flu) vaccinations are required for all NIH staff members who have direct contact with patients. COVID-19 vaccines are recommended for persons 6 months of age and older.
- Trial name
- NCT04794829
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
SARS-CoV Infection, Polymerase Chain Reaction
Self-Collected Saliva Samples Without Viral Transport Media for COVID-19 Testing Via RT-PCR
This is a study that will attempt to validate the process for detecting SARS-CoV-2 (COVID19) on a non-FDA-approved technology using self-collected saliva as the specimen.
- Conditions
- SARS-CoV Infection, Polymerase Chain Reaction, Laboratory Testing
- Trial name
- NCT04604145
- Testing
- SARS-CoV-2 testing on the Eppendorf Thermal Cycler PCR system using self-collected saliva as the specimen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
COVID-19
Preop COVID Testing Patterns
This study is an investigation of preoperative asymptomatic COVID screening nationwide. The hypothesis is that because these tests are performed without reference to pretest probability of COVID-19 disease, unlike tests based on…
- Trial name
- NCT04838119
- Where
- United States
- Volunteers
- 375,692 people
- Sponsor
- Wake Forest University Health Sciences
Pregnancy
Assessment of Obstetric, Fetal and Neonatal Risks and Vertical SARS-CoV-2 Transmission During COVID-19 Pandemic
A new coronavirus (COVID-19) highlighted at the end of 2019 in China is spreading across all continents. Most often at the origin of a mild infectious syndrome, associating benign symptoms (such as fever, cough, and headache) to…
- Trial name
- COroFet (NCT04360811)
- Testing
- COVID 19 diagnostic test by PCR
- Where
- France
- Volunteers
- 2,494 people
- Sponsor
- University Hospital, Toulouse
Covid19
Artificial Intelligence - SARS-CoV-2 (COVID-19) Risk Evaluation
The management of COVID-19 patients in overwhelmed hospital facing the pandemic is a clinical challenge. The improvement of decision making may allow a better allocation of available resources and a better treatment of patients…
- Trial name
- AI-SCoRE (NCT04834934)
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Inflammation
Impact of Acute and Chronic Inflammation on Cytochromes P450 Activity Measured With Dried Blood Spot
Cytochromes P450, main enzymes of drug metabolism, play a prominent role in the first-pass metabolism of oral substances. Inter-individual variability in their activity due to genetic and environmental factors has been observed…
- Trial name
- NCT03262051
- Testing
- CYP phenotyping
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- University Hospital, Geneva
Multiple Sclerosis, COVID-19
COVID-19 on Disease Activity in Radiologically Isolated Syndrome Cohort
The Radiologically Isolated Syndrome (RIS) is defined as incidental Magnetic Resonance Imaging (MRI) abnormalities fulfil the criteria for dissemination in space, suggestive of multiple sclerosis.
- Trial name
- VaxiRIS (NCT05387395)
- Testing
- NO intervention
- Where
- France
- Volunteers
- 217 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
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