Clinical trials: Creatine
Nutritional Supplements
Safety of Different Forms of Creatine
This study will aim to determine whether ingesting creatine nitrate (CrN) at higher doses will differentially affect hemodynamic variables compared to a placebo.
- Trial name
- NB9 (NCT03039829)
- Testing
- Creatine nitrate, low dose, Creatine nitrate, high dose
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Nutritional Status
Effect of Using Whey Protein and Creatine Supplements on Muscular Strength in Weight-training Adult Males
The purpose of this study was to evaluate the effect of combined whey protein and creatine supplement, as compared with whey protein supplement alone, on change in upper and lower body strength.
- Trial name
- NCT02094781
- Testing
- Whey protein and creatine supplement, Whey protein only supplement
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Anaerobic Performance, Cognitive Performance
Acute Effects of Creatine and L-Arginine Co-Supplementation on Anaerobic and Cognitive Performance in Recreationally Active Males
This randomized, double-blind, four-period crossover trial investigates the acute effects of creatine monohydrate, L-arginine, and their combined administration on anaerobic performance, jump performance, and cognitive reaction…
- Conditions
- Anaerobic Performance, Cognitive Performance, Healthy Volunteers
- Trial name
- NCT07548541
- Testing
- Creatine Monohydrate, L-Arginine
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inonu University
Proteinuria in Pregnancy
The Effect of Blood on the PC Ratio During Pregnancy
This study will examine the effect if blood on the the protein to creatine (PC) ratio in pregnant patients by adding blood to urine samples.
- Trial name
- NCT05434845
- Testing
- Blood draw
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marshall University
Rhabdomyolysis, Myopathy
The Association of Genetic Polymorphisms With Statin-Induced Myopathy.
To observe not only the distribution of single nucleotide polymorphism in genes related with pharmacodynamic and pharmacokinetics alteration of statins but also to analyze the correlation between these SNPs and the incidence of…
- Trial name
- NCT00549029
- Testing
- DNA
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Muscle Damage
Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars.
- Trial name
- NCT06086691
- Testing
- Strength Training with Caffeine, Endurance Training with Caffeine
- Where
- Pakistan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Creatine, High Intensity Interval Training
High Intensity Interval Training, Creatine Intake and Anaerobic Power
Creatine is an ergogenic aid with positive effects on muscle and performance. The aim of the study was to determine whether there is a difference between the effects of creatine supplementation taken together with Wingate-based…
- Trial name
- NCT05981820
- Testing
- Creatine, HIIT training
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ankara University
Healthy
Creatine Supplementation on Cognition in Children
Creatine supplementation may improve cognitive function in elderly and vegetarian individuals. This study aims to investigate the role of creatine supplementation on cognitive function in healthy children.
- Trial name
- NCT01803230
- Testing
- creatine supplementation
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Energy Metabolism
Guanidinoacetic Acid With Creatine Compared With Creatine Alone for Tissue Bioenergetics, Hyperhomocysteinemia and Exercise Performance
Co-administration of creatine and guanidinoacetic acid (GAA) has been recently put forward as an advanced dietary strategy to optimize tissue bioenergetics.
- Trial name
- NCT03350282
- Testing
- GAA-creatine, Creatine
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Hyperhomocysteinemia
The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers
A methyl-group acceptor such as guanidinoacetic acid (GAA) could induce hyperhomocysteinemia with the effects of GAA expected to be dose-dependent.
- Trial name
- NCT01371357
- Testing
- TEST 1, TEST 2, TEST 3
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia
Resistance Training, Sports Nutrition
Effects of Three Carbohydrate Beverages on Resistance Training Performance
This randomized, triple-blinded, counterbalanced crossover trial compared three carbohydrate beverages that provided the same amount of carbohydrate (30 g) but differed in carbohydrate source: dextrose, maltodextrin, and highly…
- Conditions
- Resistance Training, Sports Nutrition, Dietary Carbohydrates
- Trial name
- NCT07874776
- Testing
- Dextrose, Maltodextrin, Highly Branched Cyclic Dextrin
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Aging, Sarcopenia
Effect of Creatine+HMB Supplementation in Physically Active Older Adults
Sarcopenia (SAR) is the loss of muscle strength and mass caused by aging. It is accompanied by a progressive decline in physical and cognitive abilities, increasing the risk of falls.
- Conditions
- Aging, Sarcopenia, Nutrition, Healthy
- Trial name
- CRESHARE (NCT05951439)
- Testing
- CRE + HMB
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Burgos
Neurologic Diseases, General
Intranasal Administration of Dodecyl Creatine Ester (CBT101) in Healthy Male Subjects
A Phase 1, Randomized, Double-Blinded, Placebo-Controlled study to Evaluate the Safety, Tolerability,and Pharmacokinetics of Single and Multiple Ascending Doses of CBT101 given intranasally in Healthy Male Subjects.
- Trial name
- CBT101 (NCT07050316)
- Testing
- CBT101
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ceres Brain Therapeutics
Aging, Muscle Loss
D3-Creatine and Skeletal Muscle in Older Adults
The age-related decline in muscle mass and strength are collectively referred to as sarcopenia. However, the tools currently employed to assess skeletal muscle mass (SMM) (e.g., Dual-energy Xray Absorptiometry; DXA) have…
- Trial name
- D3-Cr (NCT06630949)
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- McMaster University
Physical Fitness
Measuring Uniformed Servicemembers' Fitness Scores on Creatine Loading and Exercise
The purpose of this study is to compare the physical fitness performance-as measured by the Air Force Physical Fitness Test (PFT)-of subjects that, in conjunction with exercise, will take creatine supplementation over a four week…
- Trial name
- MUSSCLE (NCT02661334)
- Testing
- Creatine Monohydrate, Rice Flour
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- David Grant U.S. Air Force Medical Center
Healthy Subjects
Effects of Betaine Supplementation on Strength and Muscle Creatine Content
It has been suggested that betaine supplementation may improve muscle strength by increasing muscle creatine content. However, there is no data supporting this assumption.
- Trial name
- NCT01213719
- Testing
- creatine, betaine, dextrose
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy
Pomegranate Improve Biological Recovery Kinetics in Elite Weightlifter
From the recent scientific literature in the field of biological response to physical exercise, a significant increase in muscle damage, soreness and inflammation were registered immediately and even 48 after resistance exercise.
- Trial name
- NCT02697903
- Testing
- Natural Pomegranate Juice
- Where
- Tunisia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Athletic Performance, Physical Endurance
Event-Specific Adaptations to CrossFit and Running-Based HIIT in Elite Distance Runners at Moderate Altitude
The goal of this clinical trial is to compare the effects of two high-intensity training programs on physical performance and physiological adaptations in elite male middle- and long-distance runners aged 25 to 35 years who live…
- Conditions
- Athletic Performance, Physical Endurance, Altitude Training Adaptation, Aerobic Capacity
- Trial name
- NCT07675577
- Testing
- Running-Based High-Intensity Interval Training (HIIT), CrossFit-Based High-Intensity Training (CF)
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Sarcopenia
Creatine HCl Supplementation in Sarcopenia: A Randomized Controlled Study
The CONCRET-SARCOPA trial is a 12-week, double-blind, randomized controlled study designed to evaluate the efficacy of creatine HCl supplementation in older adults with sarcopenia.
- Trial name
- SARCOPA (NCT07285226)
- Testing
- Experimental 1, Experimental 2
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Center for Health Sciences, Serbia